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Shaojun Bai,Chunlong Li,Xiangyu Fu,Jian Liu,Shuming Wen 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.61 No.-
The interaction between sulfide-ion species and smithsonite surfaces in the absence with and without ammonia liquor was investigated. The results of zeta potential and sulfide ion adsorption indicated that NH3·H2O addition promoted the transfer of sulfur in the pulp solutions onto the smithsonite surfaces. Time-of-flight secondary ion mass spectrometry and X-ray photo-electron spectroscopy analysis indicated that the zinc sulfide species was composed of zinc monosulfide and zinc polysulfide and was reinforced by NH3·H2O addition. The distribution ratio of polysulfide in the whole S species increased. The results shed light on reinforcement of the smithsonite sulfidation mechanism with ammonia liquor addition.
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Zuoguang Wang,Ya Liu,Jieling Liu,Qiuli Niu,Jie Wen,Shaojun Wen,Zhaosu Wu 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.3
Purpose: Mitofusin2 gene (Mfn2, also named Hyperplasia suppressive gene, HSG) is very important in the origin and development of hypertension. However, the mechanism of Mfn2/HSG expression regulation was not uncovered. This study was designed to explore the association of a novel 5’-uncoding region (UCR) -1248 A>G variation of HSG/Mfn2 gene and hypertension. Materials and Methods: 472 healthy, normotensive subjects [normotension (NT) group], 454 prehypertensive subjects [prehypertension (PH) group] and 978 hypertensive patients [essential hypertension (EH) group] were screened for an association study between 5’-UCR -1248 A>G of Mfn2/HSG and hypertension by polymerase chain reaction and DNA sequencing after venous blood was drawn and DNA was extracted. Results: When comparing the A and G frequency in EH, PH and NT groups, in total, NT group significantly had higher A frequency than in PH group [odds ratio (OR)=1.605, confidence interval (CI) 95%=1.063-2.242, p=0.025] and EH group (OR=5.395, CI 95%=3.783-7.695, p<0.01). When subgrouped by gender, A frequency in NT group was still significantly higher than in EH group (male: OR= 4.264, CI 95%=2.780-6.543, p<0.01; female: OR=8.897, CI 95%=4.686-16.891, p<0.01), but not from PH group, either in male group or in female group. Ordinal Logistic Regression analysis showed that A>G variation was significantly related with blood pressure level (B=-1.271, Wald=40.914, CI 95%=-1.660 - -0.881, p<0.01). Conclusion: 5’-UCR -1248 A>G variation of Mfn2/HSG gene was a novel variation and may be associated with hypertension in Chinese.
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