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Shading Effect of Different Colored Polyethylene net on Seeding Growth of Panax ginseng C. A. Meyer
Sung-Woo Lee,Seon-Woo Cha,Dong-Yun Hyun,Young-Chang Kim,Seung-Won Kang,Nak-Sul Seong 韓國藥用作物學會 2006 한국약용작물학회지 Vol.14 No.2
This study was carried out to investigate spectral irradiance characteristics of blue, yellow, and blue-black colored polyethylene (PE) shading net and the effect on growth characteristics and yield in ginseng seedling. The spectral irradiance (μmol/m2/s/nm) showed the peak at 498 nm in both of blue and blue-black PE shading net, and 606 nm under yellow PE one. The intensity of blue light in blue shading was more strong than that of blue-black shading, control. Blue shading was increased by 17% and 23% in accumulated quantum for daytime, 0.5℃ and 0.2℃ in maximum temperature on June 2 than that of yellow and blue-black shading, respectively, but heat injury ratio of the former was lower than that of the latter. Chlorophyll content and stem length in blue shading were decreased more significantly than those of yellow and blue-black shading. The specific leaf weight was higher under blue and yellow shading than that of blue-black shading. Ginseng seedling harvested in blue shading was increased by 13~17% in the number of root, and 17~20% in root weight per m 2 compared to yellow and blue-black shading owing to the increase of survived plant, and the decrease of specific leaf weight, heat injury ratio, and stem length.
A 13-week subchronic toxicity study of an <i>Eriobotrya japonica</i> leaf extract in rats
Seong, Nak-Won,Seo, Heung-Sik,Kim, Jun-Ho,Kim, Yong-Jae,Kim, Eun,Lee, Joon-Yeol,Ko, Je-Won,Kim, Jong-Choon Elsevier 2018 Journal of Ethnopharmacology Vol.226 No.-
<P><B>Abstract</B></P> <P><B>Ethnopharmacological relevance</B></P> <P> <I>Eriobotrya japonica</I> leaf is widely used in traditional medicine, and exhibits various beneficial effects such as anti-inflammatory, antiviral, antioxidant, and antitumor activities. However, limited data are available on the potential adverse effects of <I>E. japonica</I>.</P> <P><B>Aim of the study</B></P> <P>This study investigated the potential subchronic toxicity of an <I>E. japonica</I> leaf extract (EJE) through a 13-week repeated oral dose experiment in Sprague–Dawley rats.</P> <P><B>Materials and methods</B></P> <P>Forty male and 40 female rats were randomly assigned to four experimental groups: three treatment groups receiving 250, 500, and 1000 mg/kg/day of EJE and a vehicle control group receiving sterile distilled water for 13 weeks.</P> <P><B>Results</B></P> <P>Repeated oral administration of EJE for 13 weeks did not cause any treatment-related adverse effects with respect to clinical symptoms, body weight, food and water consumption, urinalysis, ophthalmology, necropsy findings, hematology, serum biochemistry, organ weight, and histopathological examination at any dose tested. Although some changes were observed in clinical symptoms, organ weight, hematology, and histopathology, these findings did not show a dose–response relationship and were within normal historical ranges for control rats.</P> <P><B>Conclusion</B></P> <P>Under the present experimental conditions, the no-observed-adverse-effect level of EJE was > 1000 mg/kg/day in both sexes and no target organs were identified. The results suggest that the EJE is a safe traditional medicine for clinical applications at proper dose.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Repeated dose 90-day oral toxicity of 20nm, positive charged Zinc Oxide Nanoparticles in SD rats
Nak-Won Seong,Eun-Ho Maeng,Su-Hyun Kim,Jin-Hee Lee,Sung-Sup Shin,Jun-Ho Kim,Taek-Jin Lee,Seon-Ju Kim,Hak-Su Park,Sang-Bum Koh,Eun-Jeong Lee,Yu-Ri Kim,Meyoung-Kon Kim 한국실험동물학회 2013 한국실험동물학회 학술발표대회 논문집 Vol.2013 No.2
구척(狗脊)이 흰쥐의 척수압박에 의한 신경세포 손상에 미치는 영향
박원상 ( Won Sang Park ),김은석 ( Eun Seok Kim ),신정원 ( Jung Won Shin ),김범회 ( Bum Hoi Kim ),김성준 ( Seong Joon Kim ),강희 ( Hee Kang ),손낙원 ( Nak Won Sohn ) 한방재활의학과학회 2010 한방재활의학과학회지 Vol.20 No.2
Objectives: This study was performed to evaluate the effects of root of Cibotii rhizoma(CR) ethanol extract on the tissue and neuronal damage of the spinal cord injury(SCI). Methods :SCI was induced by mechanical contusion following laminectomy of 10th thoracic vertebra in Sprague-Dawley rats. CR was orally given once a day for 7 days after SCI. Tissue damage and nerve fiber degeneration were examined with cresyl violet and luxol fast blue(LFB) histochemistry. HSP72(as neuronal damage marker), MAP2(as nerve fiber degeneration marker), c-Fos(immediate early gene), and Bax(pro-apoptotic molecule) expressions were examined using immuno-histochemistry. Individual immuno-positive cells expressing HSP72, MAP2, c-Fos and Bax were observed on the damaged level and the upper thoracic and lower lumbar spinal segments. Results :1. CR reduced degeneration of nerve fibers and motor neuron shrinkage in the ventral horn of the lower lumbar spinal segment, but generally it did not seem to ameliorate the tissue injury following SCI. 2. CR reduced demyelination in the ventral and lateral funiculus of the lower lumbar spinal segment. 3. CR reduced HSP72 expression on the neurons in the peri-central canal gray matter adjacent to the damaged region. 4. CR strengthened MAP2 expression on the motor neurons in the ventral horn and on nerve fibers in the lateral funiculus of the lower lumbar spinal segment. 5. CR reduced c-Fos positive cells in the peri-lesion and the dorsal horn of the damaged level and in the ventral horn of the lower lumbar spinal segment. 6. CR reduced Bax positive cells in the peri-lesion and the dorsal horn of the damaged level and in the ventral horn of the lower lumbar spinal segment. Conclusions :These results suggest that CR plays an inhibitory role against secondary neuronal damage and nerve fiber degeneration following SCI.
정낙탁(Nak-Tak Jeong),양성모(Seong-Mo Yang),김광섭(Kwang-Seup Kim),이슬기(Seulgi Lee),신희진(Heehin Shin),김현수(Hyunsoo Kim),서명원(Myung-Won Suh) 한국자동차공학회 2014 한국자동차공학회 부문종합 학술대회 Vol.2014 No.5
Recently, due to various environmental problems such as global warming, increases of international oil prices, exhaustion of resource and so on, a paradigm of world automobile market is rapidly changing from internal combustion engine to eco-friendly vehicles using electric power such as EV (Electric Vehicle), HEV (Hybrid Electric Vehicle), PHEV (Plug-in Hybrid electric Vehicle) and FCEV (Fuel Cell Electric Vehicle). However, there are many driving cycles for performance evaluation of conventional vehicles but, there is a lack of researches on driving cycle for EV. In this study, in order to develop urban driving cycle for performance evaluation of electric vehicles, Gwacheon-city patrol route of police patrol car was selected, actual driving test was performed using EV. The driving data such as velocity, time, GPS information etc. was recorded. Through the analysis results of recorded data, GUDC-EV (Gwacheon-city Urban Driving Cycle for Electric Vehicles) including road gradient was developed.
Park, Seong-Kyu,Won, Jong-Ho,Kim, Hyun-Jung,Bae, Sang-Byung,Kim, Chan-Kyu,Lee, Kyu-Taeg,Lee, Nam-Su,Lee, You Kyoung,Jeong, Dae-Chul,Chung, Nak-Gyun,Kim, Hyun-Soo,Hong, Dae-Sik,Park, Hee-Sook The Korean Academy of Medical Sciences 2007 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.22 No.3
<P>Mesenchymal stem cells (MSCs) have recently been identified and characterized in humans. Moreover, MSC secrete cytokines that can support hematopoietic progenitor growth. In the present study, we evaluated whether the efficacy of hematopoietic stem cell transplantation is improved by their co-transplantation with MSC, and whether this is positively correlated with the dose of infused MSCs. Accordingly, irradiated NOD/SCID mice were transplanted with 1×10<SUP>5</SUP> human CD34+ cells in the presence or absence of culture expanded MSCs (1×10<SUP>6</SUP> or 5×10<SUP>6</SUP>). We evaluated human hematopoietic cell engraftment by flow cytometry and assessed MSC tissue distributions by fluorescence in situ hybridization. We found that CD45+ and CD34+ cell levels were significantly elevated in a dose-dependent manner in cotransplanted mice 4 weeks after transplantation. The engraftments of CD33+ and CD19+ cells also increased dose-dependently. However, the engraftment of CD3+ cells did not increase after co-transplantation with MSCs. Human Y chromosome+ cells were observed in multiple tissues and were more frequently observed in mice co-transplanted with 5×10<SUP>6</SUP> rather than 1×10<SUP>6</SUP> MSCs. These results suggest that MSCs are capable of enhancing hematopoietic cell engraftment and distribution in multiple organs in a dose-dependent fashion.</P>
청소년들의 이종격투기에 대한 미디어 시청동기가 시청태도와 행동에 미치는 영향
공성배(Seong Bae Kong),성낙훈(Nak Hun Seong),배상일(Sang Il Bae),방환복(Whan Bog Bang),이원희(Won Hi Lee) 한국사회체육학회 2007 한국사회체육학회지 Vol.0 No.31
The purpose of this study is to investigate the effects of teenagers` viewing motivation of the mixed martial arts program on viewing attitude and viewing behavior. For this study, teenagers who have seen the mixed martial arts program in Sung-nam and Young-in City were selected as the population. Then, 336 teenagers chosen by systematic stratified cluster random sampling were analyzed. Exploratory Factor Analysis, Reliability Analysis and Multiple Regression were conducted by SPSS Window 12.0. The results were as follows:First, there were statistically significant differences in viewing attitude and viewing behavior according to the gender. Second, there were no statistically significant differences in viewing attitude and viewing behavior according to the school years. Third, there were statistically significant differences in viewing attitude and viewing behavior according to the viewing time. Fourth, there were statistically significant differences in viewing attitude and viewing behavior according to the viewing period. Fifth, it was found that viewing motivation significantly influences viewing attitude and explains 69.2%(R2=.268) of the variance. Vicarious satisfaction, entertainment pursuit motivation, time consuming motivation, and social exchange motivation which are subordinate constructs of viewing motivation have significantly a positive effect on viewing attitude in the order. Sixth, it was found that viewing motivation significantly influences viewing behavior and explains 69.3%(R2=.268) of the variance. Time consuming motivation, entertainment pursuit motivation, vicarious satisfaction, and social exchange motivation which are subordinate constructs of viewing motivation have significantly a positive effect on viewing behavior in the order. However, information pursuit motivation have significantly a negative effect on viewing behavior.