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Sung-Su Kim,Yee Eun Lee,ho Hyun Kim,Joong-Seok Min,Dong Gyun Yim,Cheorun Jo 한국축산식품학회 2022 한국축산식품학회지 Vol.42 No.1
The objective of this study was to determine the optimal cooking time by considering the cooking loss, shear force, and off-odor reduction of pork large intestines. Commercial pork large intestines were purchased, quartered perpendicularly, and cooked in boiling water for 40, 120, 180, and 240 min. Cooking loss of the samples increased after 240 min of cooking (10.92, p<0.05) while shear force value was lower at 240 min (4.45) compared to that at other cooking times (p<0.001). The amount of major volatile organic compounds showed a decreasing trend with increasing cooking time. In particular, the amount of methyl pentanoate (17,528.71) and methyl isobutyrate (812.51), compounds with a relatively low odor threshold, decreased significantly after 120 min of cooking and no change was observed thereafter (p<0.05). In addition, the amount of 2-pentanol (3,785.65) and 1-propanol (622.26), possibly produced by lipid oxidation, significantly decreased at the same cooking time (p<0.001). In the principal component analysis, only the 40 min cooking time was significantly different from other cooking time by high amounts of 1-propanol, 2-pentanol, and methyl isobutyrate. In conclusion, in the present study, the optimal cooking time for pork large intestines was 120 min in terms of off-odor reduction, cooking loss, and shear force.
측정 자세의 변화에 따른 맥의 변화 특성: 선 자세, 앉은 자세, 누운 자세
권선민 ( Sun Min Kown ),강희정 ( Hee Jung Kang ),이상훈 ( Sang Hun Lee ),임윤경 ( Yun Kyoung Yim ),이용흠 ( Yong Heum Lee ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.4
Objectives: Informations on pulse diagnosis in literature are based on diagnosing pulse waveforms on supine posture. However, today`s pulse waveforms are measured on various postures for the convenience of patients or doctors. For objective measurement, the effect of posture on the pulse waveforms should be considered. The objective of this study was to find posture-related changes in the radial pulse waveforms. Methods: We used an instrument, DMP-3000(DAEYOMEDI Co., Ansan, Korea), measuring radial pulse waveforms noninvasively by tonometric method. 25 male subjects participated in the trial. Before measuring radial pulse waveforms subjects had rest for 5 min. The pulse waveforms were measured on the left wrist. Each subject underwent this course on the supine, sitting, and standing posture. We analyzed pulse waveforms with Height-parameters, Time-parameters, Energy, and Elastic rate. Results: Height-parameters(h1~h5) on the supine posture were bigger than those on the sitting and standing posture. In case of Time-parameters, the parameters making up systolic time decrease in order of on standing, sitting, and supine position. However, systolic time and diastolic time didn`t have any changes. Energy of pulse was the biggest on supine posture and Elastic rate on standing posture. Conclusions: In this study we found that posture changes affect radial pulse waveforms. For quantification of the changes, more trials should be done. After analyzing much data we might apply parameters of pulse waveforms changed by posture. Also, we might diagnose special disease with properties of pulse waveforms by posture.
Moon, Seung Myung,Choi, Goang-Min,Yoo, Dae Young,Jung, Hyo Young,Yim, Hee Sun,Kim, Dae Won,Hwang, In Koo,Cho, Byung Moon,Chang, In Bok,Cho, Sung-Min,Won, Moo-Ho Kluwer Academic/Plenum Publishers 2015 Neurochem Res Vol.40 No.5
<P>In the present study, we investigated the effects of pioglitazone (PGZ) in the hippocampal CA1 region of low- or high-fat diet (LFD or HFD) fed gerbils after transient forebrain ischemia. After 8 weeks of LFD or HFD feeding, PGZ (30 mg/kg) was intraperitoneally administered to the gerbils, following which ischemia was induced by occlusion of the bilateral common carotid arteries for 5 min. Administration of PGZ significantly reduced the ischemia-induced hyperactivity 1 day after ischemia/reperfusion in both LFD- and HFD-fed gerbils. At 4 days after ischemia/reperfusion, the neurons were significantly reduced and microglial activation was observed in the hippocampal CA1 region in LFD- and HFD-fed gerbils. The microglial activation was more prominent in the HFD-fed gerbils compared to the LFD-fed gerbils. Administration of PGZ ameliorated ischemia-induced neuronal death and microglial activation in the hippocampal CA1 region 4 days after ischemia/reperfusion in the LFD-fed gerbils, but not in the HFD-gerbils. At 6 h after ischemia/reperfusion, tumor necrosis factor-α (TNF-α) and interlukin-1β (IL-1β) levels were significantly increased in the hippocampal homogenates of LFD-fed group compared to control group, and HFD feeding further increased TNF-α and IL-1β levels. PGZ treatment significantly ameliorated the increase of TNF-α and IL-1β levels in LFD-fed gerbils, not in the HFD-fed gerbils. At 12 h after ischemia/reperfusion, superoxide dismutase (SOD) and malondialdehyde (MDA) levels in hippocampal homogenates were significantly increased in the LFD-fed group compared to the control group, and HFD feeding significantly showed relatively reduction in SOD activity and increase in MDA level. PGZ administration significantly reduced the increase in MDA levels 12 h after ischemia/reperfusion in the LFD-fed gerbils, but not in the HFD-fed gerbils. These results suggest that PGZ ameliorates the neuronal damage induced by ischemia by maintaining the TNF-α, IL-1β, SOD and MDA levels in LFD-fed gerbils. In addition, HFD feeding affects the modulation of these parameters in the hippocampus after transient forebrain ischemia.</P>
변형세포와 비변형세포에서 이온형과 Transferrin 결합형 Fe - 59 와 Ga - 67섭취율의 비교
손명희(Myung Hee Sohn),최기철(Ki Chul Choi),이영환(Young Hwan Lee),이상용(Sang Yong Lee),정경호(Gyung Ho Chung),한영민(Young Min Han),김종수(Jong Soo Kim),임창열(Chang Yeol Yim) 대한핵의학회 1996 핵의학 분자영상 Vol.30 No.1
N/A Pathways both mediated by and independent of transferrin(Tf) and the TfR have been described for the accumulation of iron. Although it is not clear whether the same systems take up iron and gallium, these pathways may suggest the contention that uptake of Ga-67 can, in fact, occur by both Tf-independent and Tf-dependent systems and may share with Fe-59 in part the same mechanism for uptake. The predominant system by which uptake of both radiometals occurs may be different in the degree of the transformation af tumor. Transformed(MMSV/3T3) and untransformed(BALB/3T3) cells were incubated with luM of Ga-67-citrate of Fe-59-chloride for 15 min. at 37℃ in either the presence or absence of Tf. After then, the monolayers were washed with HBSS or PBS, and the cells were solubilized in 1% SDS for gamma well counting and protein determinations. There were similarities, as well as differences, in the pattern of uptake of Fe-59 and Ga-67 presented both in ionic from and as bound to Tf. Both radiometals appeared gain to cells in either ionic or Tf-bound forms. Transformed cells appeared to accumulate more radiometal, either Ga-67 or Fe-59 in the presence of Tf than do the their untransforemd counterparts. Conversly the presentation of either radiometal in ionic form resulted in significantly greater accumulation of metal by the untransformed cells than those transformed. The efficiency for uptake of Ga-67 or Fe-59 in the absence of Tf was greater than for uptake of the Ga-Tf or Fe-Tf. However, the magnitude of difference in efficiency of uptake was greater for Fe-59(10-fold) than for Ga-67 (3-fold). Our results Supports the theory that both Tf-independent and Tf-dependent systems for the uptake of Ga-67 both systems operate oppositely between transformed cells and those untransformed, with uptake by the predominating in transformed cells by the Tf-mediated system and in untransformed cells by the Tf-independent. The uptake of Ga-67 by tumor may share with Fe-59 in part the same mechanism.
Sang-Eun Park,Min-Yim Park,Po-Keun Han,Sang-Wha Lee* 대한화학회 2006 Bulletin of the Korean Chemical Society Vol.27 No.9
An electrostatic interaction is responsible for the attachment of gold seeds of 1-3 nm onto APTMS (3-aminopropyl trimethoxysilane)-coated silica cores in the formation of gold clusters. A surface plasmon resonance and morphology of gold clusters were significantly affected by the pH of gold colloids prepared by THPC reducing agent. Gold colloids of alkaline pH induced the heterogeneous deposition of gold seeds onto the silica nanoparticles, probably due to the continuous reduction of residual gold ions during the attachment process. Gold colloids of acidic pH induced the monodisperse deposition of gold seeds, consequently leading to the formation of smooth gold layer on the silica nanoparticles surface. The gold nanoshells (core radius = 80 nm) prepared by gold colloids of pH 3.1 exhibited the more red-shift and relatively stronger intensity of plasmon absorption bands, compared with gold nanoshells prepared by alkaline gold colloids of pH 9.7.
Real object pickup method of integral imaging using offset lens array
Yim, Junkyu,Choi, Ki-Hong,Min, Sung-Wook The Optical Society 2017 Applied Optics Vol.56 No.13
<P>We propose the pickup system of integral imaging using the offset lens array (OLA), which is a useful optical component for both the pickup and display processes. The main purpose of our system is resolving the pseudoscopic image problem of integral imaging. Also, the flipped image of integral imaging that has the wrong perspective information can be removed by adding an external barrier in the display process. In this paper, the above properties are explained in detail, and the experimental results to verify the feasibility of the proposed system are presented. We are certain that our system can also be applied to other various pickup systems based on integral imaging. (C) 2017 Optical Society of America</P>
Yim, Byoung Cheol,Song, Mi Ae,Bang, Sung Do,Yoon, Sung Ro,Lee, Ok Min Korean Society of Environmental Biology 2017 환경생물 : 환경생물학회지 Vol.35 No.3
Samples were collected between August 2016 and May 2017 at Sangju-si, Gyeongsangbuk-do, Jeju-do, and Uljin-gun, Gangwon-do. As a result, one genus and six species were newly recorded in Korea. The unrecorded indigenous genus was Borzia, and the six species were Anagnostidinema acutissimum, Komvophoron bourrellyi, Hydrocoleum stankovicii, Borzia trilocularis, Phormidium tinctorium and Pseudanabaena lohchoides. Phormidium tinctorium and Pseudanabaena lohchoides had been reported to inhabit freshwater, but in this study, these were found in brackish water. It had also been reported that B. trilocularis trichomes are composed of up to 8 cells, but in this study, a maximum of 10 cells was observed.
Sung-Min Kim,Naeun Choi,Seungkyun Hwang,Min Su Yim,Jung-Sik Lee,Gyunggoo Cho,Eun Kyoung Ryu 대한화학회 2013 Bulletin of the Korean Chemical Society Vol.34 No.11
The tissue inhibitor of metalloproteinase-2 (TIMP-2) inhibits matrix metalloproteinases activity and modulates cellular proliferation and apoptosis. The human serum albumin-TIMP-2 with folic acid conjugate (termed HT2-folate) was synthesized to promote uptake through folate receptors (FRs), and a corresponding radiolabeled compound was prepared for tumor diagnosis by positron emission tomography (PET). 68Ga-NOTAHT2- folate was synthesized from 68Ga and the NOTA chelator with HT2-folate. The fusion protein was identified using MALDI-TOF mass spectrometry. The radioligand was prepared with a high radiochemical yield. Cell-surface association of 68Ga-NOTA-HT2-folate significantly increased over time in FR-positive tumor cells. In animal PET and biodistribution studies, tumor uptake was very high as early as 1 h after radioligand injection. Folate conjugation enhanced the selective receptor-targeting efficacy of HT2 in FRexpressing tumors, and its radioligand will be useful as an in vitro tool and for in vivo tumor diagnosis by PET imaging.
Effective Partial Alkynylation of Carboxylic Acid Derivatives to Alkynyl Ketones
Sang Jun Yim,Min Hyeok Kim,안덕근 대한화학회 2010 Bulletin of the Korean Chemical Society Vol.31 No.2
The reaction of carboxylic acid derivatives such as esters, acid chlorides and acid anhydrides with alkynyl lithiums in the presence of lithium morpholinide and BF3․OEt2 gave alkynyl ketones in good yield (73-96%).