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Anti-hepatotoxic activity of Fruit pulp of Momordica dioica Roxb. (Cucurbitaceae)
Ilango, K.,Maharajan, G.,Narasimhan, S. Kyung Hee Oriental Medicine Research Center 2004 Oriental pharmacy and experimental medicine Vol.4 No.1
The Hexane Extract (HE) and Ethyl Acetate Soluble Fraction of the Methanolic Extract (EASFME) of the fruit pulp of Momordica dioica Roxb. (Cucurbitaceae) was evaluated for its anti-hepatotoxic activity in rats. Acute hepatotoxicity was induced by administering paracetamol (2 g/kg, p.o.) for 3 days. The extracts, at a dose of 400 mg/kg (p.o.) administered for 7 days exhibited a significant therapeutic effect by lowering Serum Glutamate Oxaloacetate Transaminase (SGOT), Serum Glutamate Pyruvate Transaminase (SGPT), Serum Alkaline Phosphatase (ALP) and Serum bilirubin and increasing the serum protein levels. These biochemical observations were supplemented by histopathological examination of the liver sections. The activity of extract was also comparable to the standard drug Silymarin, which is a well-known natural anti-hepatotoxic drug.
Vaila Bejjam,Ilango S. Sudhakar 대한공간정보학회 2024 Spatial Information Research Vol.32 No.3
This study conducted a comprehensive analysis of erosion and accretion rates in the Kakinada coastal zones of Andhra Pradesh using multitemporal satellite images spanning six time periods from 1972 to 2022. Two methods, End Point Rate (EPR) and Linear Regression Rate (LRR), were employed to assess erosion and accretion, revealing maximum erosion rates of -28.64 and − 31.27 m/year and maximum accretion rates of 20.11 and 22.74 m/year in the study area. These changes were attributed to natural disasters like tsunamis and cyclones and anthropogenic activities such as harbour construction, beach sand excavation, industrialization of garbage dump sites, urbanization, and domestic sewage discharge. Further analysis, using the Kalman filter model, forecasted shoreline changes, predicting erosion of -842 and − 891 m and accretion of 700 and 679 m in 2032 and 2042, respectively. Specific erosion zones were identified near Uppada, Gadimoga, and Korangi, while accretion was predominant in Kakinada, Nadakuduru, Kovvadda, and Panasapadu regions. The use of multitemporal satellite images and analytical methods highlights the crucial role of spatial information science in tracking long-term coastal changes and assessing localized erosion and accretion dynamics. These findings provide the tools for effective decision-making in safeguarding vulnerable shorelines amidst evolving environmental and human-induced challenges.
K. Ganesan,S. Ilango,Mariyappan Shanmugam,M. Farrokh Baroughi,M. Kamruddin,A.K. Tyagi 한국물리학회 2013 Current Applied Physics Vol.13 No.9
The loss of local dielectric integrity in ultrathin Al2O3 films grown by atomic layer deposition is investigated using conducting atomic force microscopy. IeV spectra acquired at different regions of the samples by constant and ramping voltage stress are analyzed for their pre- and post-breakdown signatures. Based on these observations, the thickness dependent dielectric reliability and failure mechanism are discussed. Our results show that remarkable enhancement in breakdown electric field as high as 130 MV/cm is observed for ultrathin films of thickness less than 1 nm.