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Alfredo Hierro González,Julio César Fernández Travieso,Yoandy Hernández Casas,Susana Borges González,María de los Angeles Camacho Morales,Elena Ferrer Batallie,Anaisa Roja Carralera,Yenney Reyes Nuñez 대한내과학회 2024 The Korean Journal of Internal Medicine Vol.39 No.1
Background/Aims: Abexol is a mixture of primary aliphatic alcohols purified from beeswax (Apis mellifera), that produces anti-inflammatory, antioxidant and gastroprotective effects, as well as it is safe and well tolerated. To investigate and compare the efficacy and safety of Abexol (suspension versus tablets) in patients with gastrointestinal symptoms. Methods: Monocentric study, open-label, randomized design, with two parallel groups receiving Abexol tablets (150 mg/d) or Abexol suspension (75 mg/d) for 8 weeks. Primary efficacy variable (significant improvement in the total score of Gastrointestinal Symptom Rating Scale [GSRS]). Significant reduction in the intensity of the gastrointestinal-symptoms and the reduction in the consumption of antacids are considered secondary efficacy variable. Short form-36 (SF-36) quality of life questiongenonaire was evaluated as collateral variable. Data were analyzed as per intention to treat. Results: A significantly decrease in the overall score of the survey was observed with respect to the baseline level (p < 0.001) of 81.4% in the Abexol suspension group and 77.9% in the Abexol tablets group. At the end of the trial, most gastrointestinal- symptoms disappeared or reduced significantly. The frequency of consumption of neutralizing antacids was low. The significantly improvement in the perception of the state of health obtained in the Abexol is in correspondence with the improvement achieved in some of the components evaluate in the SF-36 questionnaire. Both treatments were safe and well tolerated. Conclusions: Abexol suspension showed efficacy and safety similar to Abexol tablets in patients with gastrointestinal symptoms, but using half the dose.
del Carmen Velázquez-Martínez Guadalupe,González-Hernández Héctor,Equihua-Martínez Armando,Refugio Lomeli-Flores J.,Rojas Julio C.,Lopez-Collado Jose 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.1
Avocado production in Mexico represents an income of more than $3.2 billion dollars per year in foreign ex change. Unfortunately, several factors can limit the export of this fruit. One of such limiting factor is the avocado seed moth, Stenoma catenifer; however, its population dynamics is barely known. Therefore, is relevant to study the environmental factors affecting population changes, aimed to improve its management. In this study, we monitored the population fluctuations of S. catenifer males and explored its relationship with temperature and relative humidity by using pheromone-baited traps in Hass avocado orchards in the state of Colima, Mexico. From June 2018 to June 2019, a total of 6,836 males of the avocado seed moth were collected, with two population peaks. The first in June-August, during the fruiting stage, and the second in December-January, coinciding with the end of fruiting and flowering stages. Fruit infestation ranged from 0.0 to 65.0% in the or chards examined. Cluster analysis and principal coordinate analysis indicated that sampling time and relative humidity group together but differ from temperature. The effect of relative humidity and temperature on catches was analyzed by relating non-parametric bivariate distributions. The highest male catches were recorded at temperatures greater than 15.8 ◦ C and relative humidity greater than 60% while low relative humidity did not favor moth catches. These results may be useful to predict bioecological conditions for the occurrence of pop ulations of this pest.