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RISS 인기검색어
- 검색키워드
- 저자 : Rakesh K. Gupta (검색결과 3 건)
- 무료
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Nanoelectronics: Tunneling current in DNA–Single electron transistor
Rakesh K. Gupta,Vipul Saraf 한국물리학회 2009 Current Applied Physics Vol.9 No.11
Modern silicon-integrated circuit technology has been undoubtedly increasing computing speed every 18 to 24 months according to Moor’s prediction and further, reduction in feature dimensions is not possible without various quantum problems. Despite the fabrication of the molecular junctions (acting as quantum dots), and a CNT field-effect transistor, it is very difficult to connect a single molecule to external leads, thus preventing verification of this idea until recently. Individual molecules can perform functions identical to those of the key components of present day microcircuits. Molecular engineering extends its potential application to manufacture electronic devices at nano scale with much more sophisticated advantages over the modern day microelectronics. The reason behind forming molecular electronics may be that the society at large has a demand for smaller, faster, simpler and better technologies. Bioelectronics is one of the areas of interest that overlaps with biotechnology and includes DNA electronics and cellular computing. Electronic circuit components using single molecules have been proposed since 1974. DNA-based electronic components such as single electron transistors are also being proposed and realized. In this paper, we present the possible tunneling current under different external biasing conditions. DNA–SET model is based on tunneling properties of P-bonds (as tunneling junctions in coulomb blockade regime) in sugar–phosphate backbones of single-strand DNA molecules. Modern silicon-integrated circuit technology has been undoubtedly increasing computing speed every 18 to 24 months according to Moor’s prediction and further, reduction in feature dimensions is not possible without various quantum problems. Despite the fabrication of the molecular junctions (acting as quantum dots), and a CNT field-effect transistor, it is very difficult to connect a single molecule to external leads, thus preventing verification of this idea until recently. Individual molecules can perform functions identical to those of the key components of present day microcircuits. Molecular engineering extends its potential application to manufacture electronic devices at nano scale with much more sophisticated advantages over the modern day microelectronics. The reason behind forming molecular electronics may be that the society at large has a demand for smaller, faster, simpler and better technologies. Bioelectronics is one of the areas of interest that overlaps with biotechnology and includes DNA electronics and cellular computing. Electronic circuit components using single molecules have been proposed since 1974. DNA-based electronic components such as single electron transistors are also being proposed and realized. In this paper, we present the possible tunneling current under different external biasing conditions. DNA–SET model is based on tunneling properties of P-bonds (as tunneling junctions in coulomb blockade regime) in sugar–phosphate backbones of single-strand DNA molecules.
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Radioprotective and Antioxidant Activity of Fractionated Extracts of Berries of Hippophae rhamnoides
Rakesh Kumar Sharma,Raman Chawla,Rajesh Arora,Shikha Singh,Ravinder Kumar Sagar,Raj Kumar,Ashok Sharma,Manju L. Gupta,Surender Singh,Jagdish Prasad,Haider A. Khan,Anand Swaroop,A.K. Sinha,A.K. Gupta,R 한국식품영양과학회 2007 Journal of medicinal food Vol.10 No.1
Plants are an abundant source of medicinal compounds, some of which are useful in combating free radical-1002 (flavonoid-poor fraction) of Hippophae rhamnoideswere screened on the basis of their reducing power in the aqueousphase. REC-1001 was selected for further study, since it exhibited 27.38 times higher antioxidant activity than REC-1002.REC-1001 also showed significant (P. .05) membrane protection potential at 50 .g/mL, which was attributed to its abilityto scavenge peroxyl radicals (64.82. 1.25% scavenging within 1,440 min). A significant (P. .05) difference of 67.02% infree radical scavenging activity at 1,000 ng/mL between REC-1001 and vitamin E demonstrated the extract fraction’s worthc-tion. Further, REC-1001 was found to be nontoxic up to 200 mg/kg of body weight. This research suggests that the REC-1001 fraction of H. rhamnoidesextract is a safe and effective antioxidant nutraceutical product.
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( Thakur Deen Yadav ),( Hari Poudel ),( Vikas Gupta ),( Saroj K Sinha ),( Rakesh Kochhar ),( Virendra Singh ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Preoperative biliary drainage (PBD) prior to Pancraticodu odenectomy (PD) continues to be routine in many centres de spite sufficient evidence showing PBD to increase perioperative complications. This study was planned to see complications of PD and compare between stented and non-stented. Methods: Total 59 patients were enrolled in a period of one and half year. During surgery bile aspirate was sent routinely for culture sensitivity. Drain fluid amylase and LFT were obtained on day 3, 7 and 10. Morbidity was graded according to the Clavien-Dindo classification. Pancreatic fistula, haemorrhage and DGE were documented as per international guidelins. USG Abdomen was done on POD7. Patients were assessed daily for complications as per ISGPS definition. Results: Fifty Nine patients were enrolled. 21 were stented and 38 were not stented. Median age was 62 and 55 respectively.. DGE in 13 stented and 24 non-stented patients. Pancreatic fistula occurred in 7 (33%) stented and 8(21%) non -stented group. No significant difference was found in two groups.Fever was docu mented in 5 stented and 4 non-stented . Post PD haemorrhage occured in three patients and no difference between scented and non-stented. Bile culture was sterile in Two (9.5%) stented and 28 (73%) non stented patients. This was significant. Entero cocci were most common isolate on stented patients accounting for 33% . E coli were most common among non-stetted . Conclusions: We could not find significant difference in mor bidity, hospital stay and operative time between the stented and non-stented groups after Pancreaticoduodenectomy. There was significant difference in bile culture positivity.
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