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      • KCI등재

        QUANTUM CONTROL OF PARTICLES AT MATTER SURFACE OUTSIDE THE DOMAIN

        Quan-Fang Wang 경남대학교 수학교육과 2023 Nonlinear Functional Analysis and Applications Vol.28 No.1

        In this presentation, the particles at the matter surface (metal, crystal, nano) will be considered as the control target outside the physical domain. As is well known that control problems of quantum particles at surface had been investigated in various aspects in last couple of years, but the realization of control would become rather difficult than theoretical results. Especially, whether surface control would be valid? what kind of particles at what kind of matter surfaces can be controlled? so many questions still left as the mystery in the current research literature and papers. It means that the direct control sometime does not easy. On the other hands, control outside the physical domain is quite a interest consideration in mathematics, physics and chemistry. The main plan is to take the quantum systems operator (such as Laplacian $\Delta$) in the form of fractional operator ($\Delta^s , 0 < s <1 $), then to consider the control outside of physical domain. Fortunately, there are many published articles in field of applied mathematics can be referred for the achievement of the control outside of domain. The external quantum control would be a fresh concept to do the physical control, first in the theoretic, second in the computational, final in the experimental issues.

      • Human Papillomavirus Vaccine Awareness, Acceptability, and Decision-Making Factors among Chinese College Students

        Wang, Shao-Ming,Zhang, Shao-Kai,Pan, Xiong-Fei,Ren, Ze-Fang,Yang, Chun-Xia,Wang, Zeng-Zhen,Gao, Xiao-Hong,Li, Man,Zheng, Quan-Qing,Ma, Wei,Zhao, Fang-Hui,Qiao, You-Lin,Sivasubramaniam, Priya Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

        Background: College students are recommended as the target groups for catch-up human papillomavirus (HPV) vaccination. Systematical exploration of awareness, acceptability, and decision-making factors of HPV vaccination among Chinese college students has been limited. Materials and Methods: A multi-center survey was conducted in mainland China between November 2011 and May 2012. College students aged 18-22 years were stratified by their grade, gender, and major for sampling. Socio-demographic and HPV-related information such as knowledge, perceptions, acceptability, and attitudes were collected through a questionnaire. Results: A total of 3,497 undergraduates completed the questionnaire, among which 1,686 were males. The acceptability of the HPV vaccine was high (70.8%). Undergraduates from high-level universities, at lower grade, or with greater prior knowledge of HPV vaccines showed higher acceptability of HPV vaccination ($p_{trend}$ <0.001). Additionally, undergraduates with vaccination experience outside the National Expanded Program on Immunization (OR=1.29; 95%CI: 1.10-1.51) or fear of HPV-related diseases (OR=2.79; 95%CI: 2.28-3.41) were more willing to accept HPV vaccination. General knowledge of HPV vaccine was low among undergraduates, and safety was a major concern (71.05%). The majority of students wished to pay less than 300RMB for HPV vaccine and chose the Chinese Center for Disease Control and Prevention as the most appropriate venue for vaccination. Conclusions: Although most undergraduates demonstrate positive attitudes towards HPV vaccination, challenges pertaining to introduction exist in China. Corresponding proactive education and governmental subsidy to do so are urgently needed by this age-group population. Suggestions and potential strategies indicated may help shape the future HPV vaccination program in China.

      • Nested Case-control Study of Occupational Radiation Exposure and Breast and Esophagus Cancer Risk among Medical Diagnostic X Ray Workers in Jiangsu of China

        Wang, Fu-Ru,Fang, Qiao-Qiao,Tang, Wei-Ming,Xu, Xiao-San,Mahapatra, Tanmay,Mahapatra, Sanchita,Liu, Yu-Fei,Yu, Ning-Le,Sun, Quan-Fu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

        Medical diagnostic X-ray workers are one occupational group that expose to the long-term low-dose external radiation over their working lifetime, and they may under risk of different cancers. This study aims to determine the relationship between the occupational X-ray radiation exposure and cancer risk among these workers in Jiangsu, China. We conducted Nested case-control study to investigate the occupational X-ray radiation exposure and cancer risk. Data were collected through self-administered questionnaire, which includes but not limits to demographic data, personal behaviors and family history of cancer. Retrospective dose reconstruction was conducted to estimate the cumulative doses of the x-ray workers. Inferential statistics, t-test and 2 tests were used to compare the differences between each group. We used the logistic regression model to calculate the odds ratio (OR) and 95% confidence interval (CI) of cancer by adjusting the age, gender. All 34 breast cancer cases and 45 esophageal cancer cases that detected in a cohort conducted among health workers between 1950~2011 were included in this presented study, and 158 cancer-free controls were selected by frequency-matched (1:2). Our study found that the occupational radiation exposure was associated with a significantly increased cancer risk compared with the control, especially in breast cancer and esophageal cancer (adjusted OR=2.90, 95% CI: 1.19-7.04 for breast cancer; OR=4.19, 95% CI: 1.87-9.38 for esophageal cancer, and OR=3.43, 95% CI: 1.92-6.12 for total cancer, respectively). The occupational X-ray radiation exposure was associated with increasing cancer risk, which indicates that proper intervention and prevention strategies may be needed in order to bring down the occupational cancer risk.

      • Fangchinoline Inhibits Cell Proliferation Via Akt/GSK-3beta/cyclin D1 Signaling and Induces Apoptosis in MDA-MB-231 Breast Cancer Cells

        Wang, Chang-Dong,Yuan, Cheng-Fu,Bu, You-Quan,Wu, Xiang-Mei,Wan, Jin-Yuan,Zhang, Li,Hu, Ning,Liu, Xian-Jun,Zu, Yong,Liu, Ge-Li,Song, Fang-Zhou Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        Fangchinoline (Fan) inhibits cell proliferation and induces apoptosis in several cancer cell lines. The effects of Fan on cell growth and proliferation in breast cancer cells remain to be elucidated. Here, we show that Fan inhibited cell proliferation in the MDA-MB-231 breast cancer cell line through suppression of the AKT/Gsk-3beta/cyclin D1 signaling pathway. Furthermore, Fan induced apoptosis by increasing the expression of Bax (relative to Bcl-2), active caspase 3 and cytochrome-c. Fan significantly inhibited cell proliferation of MDA-MB-231 cells in a concentration and time dependent manner as determined by MTT assay. Flow cytometry analysis demonstrated that Fan treatment of MDA-MB-231 cells resulted in cell cycle arrest at the G1 phase, which correlated with apparent downregulation of both mRNA and protein levels of both PCNA and cyclin D1. Further analysis demonstrated that Fan decreased the phosphorylation of AKT and GSK-3beta. In addition, Fan up-regulated active caspase3, cytochrome-c protein levels and the ratio of Bax/Bcl-2, accompanied by apoptosis. Taken together, these results suggest that Fan is a potential natural product for the treatment of breast cancer.

      • Outcome-based Contractors Selection using the Integrated Fuzzy AHP and Fuzzy TOPISIS Method

        Fang Wang,Quan Shi,Zhi-wei Hu,Wei Xia 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.4

        Based on the concept of outcome-based maintenance, the outcome-based contractor equipment support is proposed as the logistical support strategy in the military industry. The outcome-based contractor equipment support is focus on the combat efficiency rather than on the performance of the equipments. Choosing the right contractor is a very important part in the process of its implementation. In fact, the contractor selection is a multi-criteria decision-making problem, which is largely dependent on the uncertainty and ambiguity of the decision-makers. This paper presents a systematic decision-making process of the outcome-based contractor selection, which employs fuzzy AHP to determine the importance weights of each index and adopts fuzzy TOPSIS to obtain the performance ratings of the alternative contractors. Finally, the validity of this method is verified by a specific case.

      • KCI등재

        Coenzyme Q10 Production by Sphingomonas sp. ZUTE03 with Novel Precursors Isolated from Tobacco Waste in a Two-Phase Conversion System

        ( Le Quan Qiu ),( Wei Jian Wang ),( Wei Hong Zhong ),( Li Zhong ),( Jian Jun Fang ),( Xuan Zhen Li ),( Shi Jin Wu ),( Jian Meng Chen ) 한국미생물 · 생명공학회 2011 Journal of microbiology and biotechnology Vol.21 No.5

        Coenzyme Q10 (CoQ10) is a widely used supplement in heart diseases treatment or antioxidative dietary. The microbial production of CoQ10 was enhanced by addition of solanesol and novel precursors recovered from waste tobacco. The novel precursors were separated by silica gel and identified as α-linolenic acid (LNA) and butylated hydroxytoluene (BHT) based on the effect on CoQ10 production and GC-MS. The effects of novel precursors on CoQ10 production by Sphingomonas sp. ZUTE03 were further evaluated in a two-phase conversion system. The precursor`s combination of solanesol (70mg/l) with BHT (30mg/l) showed the best effect on the improvement of CoQ10 yield. A maximal CoQ10 productivity (9.5 mg l-1 h-1) was achieved after 8h conversion, with a molar conversion rate of 92.6% and 92.4% on BHT and solanesol, respectively. The novel precursors, BHT and LNA in crude extracts from waste tobacco leaves, might become potential candidates for application in the industrial production of CoQ10 by microbes.

      • KCI등재

        Experimental Study on Magnesium Sulfate Cement Concrete Splices of Widened Box Girder

        Li-fang Zhang,Jun Yan,Hai-yan Ma,Hong-fa Yu,Ying Wang,Qi-quan Mei 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.12

        The connecting part of bridge widening undertakes complicated forces and tends to crack. Basic magnesium sulfate cement concrete has excellent properties such as ideal early strength and tensile strength, meeting the performance requirements of joint materials. Experiments of two spliced box girder specimens with C40 basic magnesium sulfate cement concrete (MC) and normal Portland cement concrete (NC) as joint materials are carried out. Concrete strain, reinforcement strain, deflection and crack propagation law of the joint section are tested and analyzed under symmetrical loading at the cantilever of the box girders. The study shows when MC material is used in the splicing section, the joint section showed a multi-cracks failure mode with an ultimate load ratio of 0.99 and a maximum crack width of 1.3 mm; NC joint section has only three longitudinal cracks with an ultimate load ratio of 0.97 and a maximum crack width of 0.98 mm. Under the same load, the crack width and the deflection of mid-span MC joint section are greater than which of NC joint section. The maximum deflection of NC splicing section is 1.20 mm, which is 1/633 of the calculating span length. The maximum deflection of MC spliced section is 2.03 mm, which is 1/374 of the calculating span length. Comparison of the maximum deflection and the maximum crack width shows that MC material has better ductility.

      • SCOPUSKCI등재

        Study on Thermodynamics of Three Kinds of Benzindocarbocyanine Dyes in Aqueous Methanol Solution

        Huang, Wei,Wang, Lan-Ying,Fu, Yi-Le,Liu, Ji-Quan,Tao, You-Ni,Fan, Fang-Li,Zhai, Gao-Hong,Wen, Zhen-Yi Korean Chemical Society 2009 Bulletin of the Korean Chemical Society Vol.30 No.3

        Aggregation behavior of three kinds of benzindocarbocyanine dyes in aqueous methanol solution was studied by UV-Vis absorption spectrum. The results indicated that the three dyes all existed monomer-dimer equilibrium in aqueous methanol solution (concentration range $10^{−5}\;to\;10^{−6}$ M) at 25.0$\sim$41.0 ${^{\circ}C}$ for Dye 1, 28.0$\sim$49.0 ${^{\circ}C}$ for Dye 2 and 26.0$\sim$47.0 ${^{\circ}C}$ for Dye 3. The fundamental property of the three dyes as the dimeric association constant KD, the dimeric free energy ${\Delta$}G_D, the dimeric entropy ${\Delta$}S_D, and the dimeric enthalpy ${\Delta$}H_D were determined. The ${\Delta$}H_D of three dyes: Dye 1, Dye 2 and Dye 3 was -42.5, -15.1 and -18.9 kJ/mol, respectively. The experimental observations were the subject of a theoretical study including the ground-state geometries which were fully optimized using DFT at B3LYP/6-31G level. The effect of dye molecule structure on ${\Delta$}H_D was discussed by theoretical calculations.

      • Functional Roles of Long Non-coding RNA in Human Breast Cancer

        Ye, Ni,Wang, Bin,Quan, Zi-Fang,Cao, San-Jie,Wen, Xin-Tian,Huang, Yong,Huang, Xiao-Bo,Wu, Rui,Ma, Xiao-Ping,Yan, Qi-Gui Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15

        The discovery of long noncoding RNA (LncRNA) changes our view of transcriptional and posttranscriptional regulation of gene expression. With application of new research techniques such as high-throughput sequencing, the biological functions of LncRNAs are gradually becoming to be understood. Multiple studies have shown that LncRNAs serve as carcinogenic factors or tumor suppressors in breast cancer with abnormal expression, prompts the question of whether they have potential value in predicting the stages and survival rate of breast cancer patients, and also as therapeutic targets. Focusing on the latest research data, this review mainly summarizes the tumorigenic mechanisms of certain LncRNAs in breast cancer, in order to provide a theoretical basis for finding safer, more effective treatment of breast cancer at the LncRNA molecular level.

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