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RISS 인기검색어
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- 저자 : Pui-wan Cheng (검색결과 2 건)
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Cognition, Metacognition, and Metacognitive Theory : A Critical Analysis
Pui-wan Cheng 대한사고개발학회 1999 The International Journal of Creativity & Problem Vol.9 No.1
This paper offers a critical analysis of the validity and utility of metacognition as an independent construct for psychological studies. To examine the construct validity of metacognition, the relationship between cognition and metacognition is first analyzed and the conceptual issues involved in the study of metacognition are then examined. To demonstrate the construct utility of metacognition, theoretical perspectives from different areas of psychological studies with a metacognitive focus are presented. It is concluded that metacognition, with its emphasis on the superordinate role of awareness and control in directing cognitive activities and its linkage to motivational correlates, is a valid and useful concept that generates important insights into the conditions and mechanisms of human performance.
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Grace G.L. Yue,Sau-Wan Cheng,Hua Yu,Zi-Sheng Xu,Julia K.M. Lee,Po-Ming Hon,Mavis Y.H. Lee,Edward J. Kennelly,Gary Deng,Simon K. Yeung,Barrie R. Cassileth,Kwok-Pui Fung,Ping-Chung Leung,Clara B.S. Lau 한국식품영양과학회 2012 Journal of medicinal food Vol.15 No.3
The rhizome of Curcuma longa (turmeric) is often used in Asia as a spice and as a medicine. Its most wellstudied component, curcumin, has been shown to exhibit poor bioavailability in animal studies and clinical trials. We hypothesized that the presence of lipophilic components (e.g., turmerones) in turmeric extract would affect the absorption of curcumin. The effects of turmerones on curcumin transport were evaluated in human intestinal epithelial Caco-2 cells. The roles of turmerones on P-glycoprotein (P-gp) activities and mRNA expression were also evaluated. Results showed that in the presence of a- and aromatic turmerones, the amount of curcumin transported into the Caco-2 cells in 2 hours was significantly increased. a-Turmerone and verapamil (a P-gp inhibitor) significantly inhibited the efflux of rhodamine-123 and digoxin (i.e.,inhibited the activity of P-gp). It is interesting that aromatic turmerone significantly increased the rhodamine-123 efflux and Pgp (MDR1 gene) mRNA expression levels. The effects of a- and aromatic turmerones on curcumin transport as well as P-gp activities were shown here for the first time. The presence of turmerones did affect the absorption of curcumin in vitro. These findings suggest the potential use of turmeric extract (including curcumin and turmerones), rather than curcumin alone, for treating diseases.
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