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Zhao, Pin,Kim, Seohan,Yoon, Seonghwan,Song, Pungkeun Elsevier 2018 THIN SOLID FILMS - Vol.665 No.-
<P><B>Abstract</B></P> <P>Indium zinc oxide/silver/indium zinc oxide multilayer structures with a very low resistivity and high transmittance were deposited on a polyethylene terephthalate substrate by DC magnetron sputtering. The electrical, optical, mechanical, and thermal properties of the multilayer films were investigated at different Ag layer thicknesses (10–20 nm). The multilayers demonstrated relatively constant resistance change (<I>∆R</I>/ <I>R</I> <SUB>0</SUB>) over repeated bending tests with a radius of 8 mm. Efficient Joule heating could increase the operating temperature of the film heaters (7.3 Ω/□) to 73.7 °C in ~20 s at 3 V; moreover, the heat distribution remained uniform after bending tests. A high transmittance (84.7%) at a wavelength of 550 nm and low sheet resistance (7.3 Ω/□) of the optimized multilayer was obtained at an Ag layer thickness of 15 nm. These results indicate that the multilayers are promising as transparent film heaters for next-generation flexible applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Indium Zinc Oxide (IZO)/Ag/IZO multilayer used in flexible Thin Film Heaters (TFHs). </LI> <LI> Uniform heat distribution of the heater before and after bending test. </LI> <LI> IZO/Ag/IZO multilayer with 15-nm Ag layer was demonstrated to be the best combination. </LI> </UL> </P>
Electro-elastic analysis of piezoelectric laminated plates
Zhao, Minghao,Qian, Caifu,Lee, S.W.R.,Tong, Pin,Suemasu, H.,Zhang, Tong-Yi The Korean Society for Composite Materials 2007 Advanced composite materials Vol.16 No.1
Based on the Kirchhoff hypothesis of normal-remain-normal, the present work analyses piezoelectric laminated plates, wherein poled piezoelectric laminae are transversely isotropic and function as actuators. A quadric electric field is induced inside a piezoelectric lamina under a given applied voltage and mechanical bending. The governing equations for the piezoelectric laminated plate derived from the principle of virtual work in terms of the electric enthalpy have the same forms as those for a conventional composite laminated plate. We use rectangular sandwich plates of Al/PZT/Al and PZT/Al/PZT with four simply supported edges to demonstrate the prediction of the maximum bending stress in the PZT layer. The analytic solutions are verified by three-dimensional finite element analysis.
( Yuan Zhao ),( Ke Pin Chen ),( Qing Yao ),( Yang Chun Wu ),( Jian Zhang ),( Xi Jie Guo ) 한국잠사학회 2006 International Journal of Industrial Entomology Vol.13 No.2
Seveval Chinese and Japanese varieties with good characters were used in the breeding. After 5 years (15 generations), a pair of robust and high quality silkworm variety with NPV resistance was bred by means of a combination of crossing and pedigree selection complemented by the selection of NPV resistance. The variety was identified jointly nationwide in 2003 and 2004, and appraised by National Mulberry and Silkworm Appraising Committee. Results are as follows: its cocooning rate is over 93%, shell rate 23-25%, filament length 1200-1300 meters, reelability 75-88%, Length of non-broken cocoon filament 900-1100 meters, raw silk rate 17-19%, neatness 95-97 points, and cocoon crop, cocoon shell weight and raw silk weight per 10 000 larvae is higher than those of the control variety by 7-10%, 14-19% and 14-18%, respectively. The variety is not only robust, resistant to high temperature and NPV, easy to rear, uniform in hatching, molting and maturing, but also lays more eggs, and its fecundity is high. It is suitable to rear in the Yangtze River Basin, the Yellow River basin and the Pearl River basin of China.
Dietary Phytoncide Supplementation Improved Growth Performance and Meat Quality of Finishing Pigs
Li, Han Lin,Zhao, Pin Yao,Lei, Yan,Hossain, Md Manik,Kang, Jungsun,Kim, In Ho Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.9
We conducted this 10-wk experiment to evaluate the effects of dietary phytoncide, Korean pine extract as phytogenic feed additive (PFA), on growth performance, blood characteristics, and meat quality in finishing pigs. A total of 160 pigs ([Landrace${\times}$Yorkshire]${\times}$Duroc, body weight (BW) = $58.2{\pm}1.0kg$) were randomly allocated into 1 of 4 treatments according to their BW and sex, 10 replicate pens per treatment with 4 pigs per pen were used (2 barrows and 2 gilts). Dietary treatments were: CON, control diet; PT2, CON+0.02% PFA; PT4, CON+0.04% PFA; PT6, CON+0.06% PFA. Overall, average daily gain (ADG) was higher in PT4 (p<0.05) than in PT6, average daily feed intake (ADFI) was lower in PT6 than in CON (p<0.05). Besides ADFI decreased linearly (p<0.05) with the increased level of phytoncide and gain:feed ratio in PT4 treatment was higher (p<0.05) than CON treatment. During 5 to 10 weeks and overall, quadratic (p<0.05) effect was observed in ADG among the treatments. At the end of this experiment, pigs fed with PT4 diet had a greater (p<0.05) red blood cell concentration compared to the pigs fed CON diet. Water holding capacity increased linearly (p<0.05) with the increased level of phytoncide supplementation. Moreover, firmness, redness, yellowness, and drip loss at day 3 decreased linearly (p<0.05) with the increase in the level of phytoncide supplementation. In conclusion, inclusion of phytoncide could enhance growth performance without any adverse effects on meat quality in finishing pigs.
Inhibition of Nemo-like Kinase Increases Taxol Sensitivity in Laryngeal Cancer
Dong, Ji-Rui,Guo, Nan,Zhao, Jian-Pu,Liu, Pin-Duo,Feng, Hui-Hong,Li, Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12
Several studies have shown that nemo-like kinase (NLK) plays a vital role in apoptosis of cancer cells. The present research concerned effects and mechanisms of Taxol on NLK knockdown human laryngeal cancerHep-2 cell lines in vitro. Using RNAi, methyl-thiazoltetrazolium (MTT) assays, real-time RT-PCR, Western blotting and flow cytometry analysis, growth and the cell cycle progression of NLK knockdown Hep-2 cells and expression of downstream molecules were observed. Cell growth was obviously suppressed in the Taxol treated group (P<0.001, 48 hours). Cell numbers of combined Taxol-based chemotherapy with lentivirus mediated RNAi treatment group (Lv-shNLK+Taxol goup) were significantly different from NLK-specific siRNA lentivirus infected group (Lv-shNLK group) (p<0.001). Flow cytometry analysis revealed that Lv-shNLK+Taxol caused the G0/G1-phase DNA content to decrease from 44.1 to 3.33% (p<0.001) and the S-phase DNA content to increase from 38.4 to 82.0% (p<0.001), in comparison with the Lv-shNLK+Taxol group. Immunoblot analysis showed that knockdown of NLK led to significant reduction in the levels of cyclin D1, PCNA and PARP, whereas cyclin B1 was elevated in. Cell growth was also obviously suppressed in the Hep-2 cell line, knockdown of NLK making them more sensitive to Taxol treatment. NLK is expected to become a target of new laryngeal cancer gene therapies.
Li, Hai-Long,Xie, Shou-Pin,Yang, Ya-Li,Cheng, Ying-Xia,Zhang, Ying,Wang, Jing,Wang, Yong,Liu, Da-Long,Chen, Zhao-Feng,Zhou, Yong-Ning,Wu, Hong-Yan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
Background: miRNAs are relatively recently discovered cancer biomarkers which have important implications for cancer early diagnosis, treatment and estimation of prognosis. Here we focussed on expression of mir-196a-5p in gastric cancer tissues and cell lines so as to analyse its significance for clinicopathologic characteristics and generate enriched KEGG pathways clustered by target genes for exploring its potential roles as a biomarker in gastric cancer. Materials and Methods: The expression of mir-196a-5p in poorly, moderate and well differentiated gastric cancer cell lines compared with GES-1 was detected by RT-qPCR, and the expression of mir-196a-5p in gastric cancer tissues comparing with adjacent non cancer tissues of 58 cases were also assessed by RT-qPCR. Subsequently, an analysis of clinical significance of mir-196a-5p in gastric cancer and enriched KEGG pathways was executed based on the miRWalk prediction database combined with bioinformatics tools DAVID 6.7 and Mirfocus 3.0. Results: RT-qPCR showed that mir-196a-5p was up-regulated in 6 poorly and moderate differentiated gastric cancer cell lines SGC-7901, MKN-45, MKN-28, MGC-803, BGC-823, HGC-27 compared with GES-1, but down-regulated in the highly differentiated gastric cancer cell line AGS. Clinical data indicated mir-196a-5p to beup-regulated in gastric cancer tissues (47/58). Overexpression of mir-196a-5p was associated with more extensive degree of lymph node metastasis and clinical stage (P < 0.05; x2 test). Enriched KEGG pathway analyses of predicted and validated targets in miRWalk combined with DAVID 6.7 and Mirfocus 3.0 showed that the targeted genes regulated by mir-196a-5p were involved in malignancy associated biology. Conclusions: Overexpression of mir-196a-5p is associated with lymph node metastasis and clinical stage, and enriched KEGG pathway analyses showed that targeted genes regulated by mir-196a-5p may contribute to tumorgenesis, suggesting roles as an oncogenic miRNA biomarker in gastric cancer.
Kinetic Models of Controllable Pore Growth of Anodic Aluminum Oxide Membrane
Yan Huang,Hong-yan Zeng,Ce Zhao,Ye-qing Qu,Pin Zhang 대한금속·재료학회 2012 METALS AND MATERIALS International Vol.18 No.3
An anodized Al2O3 (AAO) membrane with apertures about 72 nm in diameter was prepared by two-step anodic oxidation. The appearance and pore arrangement of the AAO membrane were characterized by energy dispersive x-ray spectroscopy and scanning electron microscopy. It was confirmed that the pores with high pore aspect ratio were parallel, well-ordered, and uniform. The kinetics of pores growth in the AAO membrane was derived, and the kinetic models showed that pores stopped developing when the pressure (σ) trended to equal the surface tension at the end of anodic oxidation. During pore expansion,the effects of the oxalic acid concentration and expansion time on the pore size were investigated, and the kinetic behaviors were explained with two kinetic models derived in this study. They showed that the pore size increased with extended time (r=G·t+G’), but decreased with increased concentration (r=−K·lnc -K’)through the derived mathematic formula. Also, the values of G, G’,K, and K’ were derived from our experimental data.