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Nannan Yang,Jung E. Ha‑Brookshire 한국의류학회 2019 Fashion and Textiles Vol.6 No.1
Within the moral responsibility theory of corporate sustainability (MRCS) framework (Ha-Brookshire in J Bus Ethics, 2015. https ://doi.org/10.1007/s1055 1-015-2847-2), the study examined 86 sustainability reports from top performing textile and apparel companies in China to explore their perceptions and sustainability capability implications. Content analysis of their sustainability reports was conducted to analyze whether each company (a) perceives sustainability as a perfect duty or not, (b) has clear goals toward sustainability or not, and (c) has well-defined structures toward sustainability goals or not. Results show that 66 of the 86 reports described sustainability as a perfect duty to fulfill; 11 described as an imperfect duty, and 9 described no opinions about sustainability. Of the 66 reports, 19 explicitly showed clear goals and the evidence of organizational structures toward such goals, leading us to categorize them as truly sustainable corporations as Ha-Brookshire (2015) described. Of the 66, 43 lacked clear sustainability goals, leading us to categorize them as occasionally sustainable corporations as described by Ha-Brookshire (2015). Other firms were also categorized within the MRCS framework. Findings show a spectrum of Chinese textile and apparel companies’ sustainability capability from the moral responsibility perspective.
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Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD
Zehong Yang,Yuanyuan Yu,Nannan Sun,Limian Zhou,Dong Zhang,HaiXin Chen,Wei Miao,Weihang Gao,Canyang Zhang,Changhui Liu,Xiaoying Yang,Xiaojie Wu,Yong Gao The Korean Society of Ginseng 2023 Journal of Ginseng Research Vol.47 No.3
Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been reported to maintain glucose balance in adipose tissue, while its role in regulating lipid metabolism remain vacant. Thus, we investigated the function and mechanism of ginsenosides Rc in defending high fat diet (HFD)-induced NAFLD. Methods: Mice primary hepatocytes (MPHs) challenged with oleic acid & palmitic acid were used to test the effects of ginsenosides Rc on intracellular lipid metabolism. RNAseq and molecular docking study were performed to explore potential targets of ginsenosides Rc in defending lipid deposition. Wild type and liver specific sirtuin 6 (SIRT6, 50721) deficient mice on HFD for 12 weeks were subjected to different dose of ginsenosides Rc to determine the function and detailed mechanism in vivo. Results: We identified ginsenosides Rc as a novel SIRT6 activator via increasing its expression and deacetylase activity. Ginsenosides Rc defends OA&PA-induced lipid deposition in MPHs and protects mice against HFD-induced metabolic disorder in dosage dependent manner. Ginsenosides Rc (20mg/kg) injection improved glucose intolerance, insulin resistance, oxidative stress and inflammation response in HFD mice. Ginsenosides Rc treatment accelerates peroxisome proliferator activated receptor alpha (PPAR-α, 19013)-mediated fatty acid oxidation in vivo and in vitro. Hepatic specific SIRT6 deletion abolished ginsenoside Rc-derived protective effects against HFD-induced NAFLD. Conclusion: Ginsenosides Rc protects mice against HFD-induced hepatosteatosis by improving PPAR-α-mediated fatty acid oxidation and antioxidant capacity in a SIRT6 dependent manner, and providing a promising strategy for NAFLD.
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Parameters Design and Braking Efficiency Analysis of a Hydraulic Self-Energizing Wedge Disc Brake
Junnian Wang,Yao Zhang,Nannan Yang,Dafeng Song,Qingnian Wang 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.10
Pursuing more efficient running and operation has been the orientation of today's automotive powertrain and chassis technologies development. As for the brake system, increasing the braking efficiency or reducing the power consumption of actuation is an effective method to improve the energy-saving performance of the car. In this paper, a self-energizing wedge disc brake actuated by hydraulic power, that could be used to reduce both the actuation force and the energy required for braking is presented and compared in terms of the practical issues on braking efficiency, heat recession and self-locking. The selected critical parameters and their optimum value range are determined based on the static force analysis. Then the simulations based on AMESim/Simulink are implemented to compare the proposed wedge brake with traditional disc brake, and to investigate the influence of the wedge angle and the actuating angle on the braking efficiency performance. The simulation results validate the self-reinforcement and energy saving performance of this hydraulic wedge disc brake well.
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Xinwen Gong,Dongxue Yang,Nannan Wang,Shian Sun,Jun Nie,Guiping Ma 한국섬유공학회 2020 Fibers and polymers Vol.21 No.10
In order to improve the adsorption capacity of chitosan to organic dyes, the amino rich functionalized chitosanelectrospun nanofibers membrane was prepared. In the process of high efficiency synthesis, PGMA and PEI were grafted onthe surface of CS NFMs in turn. By means of XRD, ATR-FTIR and XPS, the successful introduction of amino group into CSwas confirmed. The selective adsorption capacity of CS-PGMA-PEI NFMs for anionic dyes was studied. The adsorptionkinetics analysis shows that the adsorption process of CS-PGMA-PEI NFMs is mainly pseudo second-order model. Itsadsorption isotherms can be described by the Langmuir model and it conforms to monolayer adsorption. The maximumadsorption capacity of Congo red calculated by Langmuir model is 657.47 mg/g. CS-PGMA-PEI NFMs has selectiveadsorption capacity for Congo red/methylene blue mixture. CS-PGMA-PEI NFMs also showed good circulation stability. This study provides a method for the synthesis of water purification membrane.
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