영어 관련 전공 학과의 개선 방안과 모형 연구

김명숙(Kim, Myungsook) 한국영어학학회 2011 영어학연구 Vol.17 No.3

This paper is a sequel to the previous study, "A study on the present and future of the English-related departments in Korean colleges" by Kim, Joon-Ho and Kim, Myungsook (April 2011). In the previous study, the results of the survey on the topic held in between May and July 2010 and participated by 138 college professors in 49 schools and 651 college students in 29 schools were statistically analyzed and discussed in detail. Continuing a research on the present and future of the English majors at 4-year universities and colleges in South Korea, this paper proposes an improved track-model for the English curriculum, a certification program for English proficiency, and a more systematic career counseling system for higher employment rate of their graduates. The track-model as well as the other programs proposed in this paper intends to provide students with flexibility in choosing the right course for their future after the students acquire a proper level of English proficiency and thus they can be promoted toward more profound level of major subjects as well as cultural-social-areal studies on English speaking countries. If the whole school system works right, the programs proposed will eventually equip students with more confidence and more competitiveness in their future.

국내 한 대학병원의 임상검체에서 분리된 Bacteroides fragilis 독소 유전자의 특성

김명숙 ( Myungsook Kim ),김현수 ( Hyunsoo Kim ),지승은 ( Seung Eun Ji ),임정훈 ( John Hoon Rim ),권선영 ( Sun Yeong Gwon ),김완희 ( Wan Hee Kim ),이기종 ( Ki Jong Rhee ),이경원 ( Kyungwon Lee ) 대한임상검사과학회 2016 대한임상검사과학회지(KJCLS) Vol.48 No.2

Enterotoxigenic Bacteroides fragilis (ETBF)는 병독소 인자로 알려진 장독소를 생성하는 균종이다. B. fragilis enterotoxin (BFT)은 bft- 1, bft- 2 및 bft- 3 세 개의 유전자 아형들이 밝혀졌다. 본 연구에서는 임상 검체에서 분리된 B. fragilis에서 bft 유전자의 유무와 BFT 음성 및 양성 균주의 항균제 내성을 조사하였다. 국내의 한 대학병원에서 8년간(2006∼2013년) 장외 검체에서 분리된 B. fragilis는 총 537주이었다. 다중중합연쇄반응으로 시험하여 bft유전자 아형을 확인하였다. BFT 음성 74주와 양성 33주를 포함한 B. fragilis 107주의 항균제 감수성은 CLSI 한천희석법으로 시험하였다. 임상 검체에서 분리된 B. fragilis의 bft 유전자 검출율은 30% 이었고, 이 중 혈액과 혈액 외 장외 검체 분리주에서는 각각 33%, 29% 이었다. ETBF 중에서 가장 흔한 아형은 bft- 1 이었고, 그 다음은 bft- 2, bft- 3 순이었다( bft- 1: 77%, bft- 2: 14%, bft- 3: 9%). BFT-음성과 양성 균주의 내성률은 일부 항균제에 대해서 차이가 있었다(BFT-음성 균주: piperacillin-tazobactam 3%, cefoxitin 5%, imipenem 1%, clindamycin 38%; BFT-양성 균주: piperacillin-tazobactam 3%, cefoxitin 6%, imipenem 3%, clindamycin 42%). BFT-음성 및 BFT-양성 균주 모두는 chloramphenicol과 metronidazole에 대한 내성은 없었다. 결론적으로, 혈액 분리주에서의 ETBF 검출율은 혈액 외 장외 검체 분리주에서와 비슷하였고, 가장 흔한 유전자 아형은 bft- 1 이었다. 항균제 내성은 BFT 양성 균주가 음성 균주보다 대체로 높았으나 통계학적으로 유의한 차이는 없었다. Enterotoxigenic Bacteroides fragilis (ETBF) produces enterotoxins known to be a virulence factor. Three isotypes of the B. fragilis toxin (BFT) gene have been identified: bft- 1, bft- 2, and bft- 3. We investigated the presence of bft isotypes in clinical B. fragilis isolates and the antimicrobial resistance of BFT-negative and BFT-positive isolates. Overall, 537 B. fragilis isolates were collected from extraintestinal specimens over 8 years (2006∼2013) from a university hospital in Korea. Samples were analyzed by multiplex PCR to identify the bft gene isotypes. Additionally, the antimicrobial susceptibility of 107 B. fragilis isolates (74 BFT-negative and 33 BFT-positive) was examined by the CLSI agar dilution method. PCR revealed a total bft gene detection rate of 30%, while 33% and 29% of blood and other extraintestinal isolates contained the gene, respectively. Among ETBF isolates, the most common isotype was bft- 1 gene, followed by bft- 2 and bft- 3 ( bft- 1 77%, bft- 2 14%, bft- 3 9%). Resistance rates (%) for BFT-negative and positive isolates differed in response to various antimicrobial agents, with 3%, 5%, 1% and 38% of BFT-negative isolates and 3%, 6%, 3% an 42% of BFT-positive isolates being resistant to piperacillin-tazobactam, cefoxitin, imipenem, and clindamycin, respectively. Interestingly, neither BFT-negative nor positive isolates showed antimicrobial resistance to chloramphenicol and metronidazole. Overall, the proportion of ETBF from blood was similar to that of other extraintestinal sites and the bft- 1 gene was the predominant isotype. Higher antimicrobial resistance rates were found in BFT-positive isolates than BFT-negative isolates, but these differences were not statistically significant.

Implementation of the effluent limitations based on the best practicable control technology for the petroleum refining industry in Korea

Kim, Jaehoon,Kim, Hyun Woo,Shin, Jin-Soo,Lee, Chul-Gu,Chung, Myungsook,Huh, In Ae,Kim, Yong-Seok Taylor Francis 2014 Desalination and Water Treatment Vol. No.

Problems in Bridging the Gap between English Spelling and Pronunciation

Myungsook Kim 한국영어학학회 1999 영어학연구 Vol.- No.8

Reversible, solid state capture of carbon dioxide by hydroxylated amidines

Kim, Myungsook,Park, Ji-Woong Royal Society of Chemistry 2010 Chemical communications Vol.46 No.14

<P>Hydroxylated amidine derivatives can capture, store, and release CO<SUB>2</SUB> reversibly in the solid state in a quantitative manner under clean and dry conditions at ambient temperature.</P> <P>Graphic Abstract</P><P>Hydroxylated amidine derivatives can capture, store, and release CO<SUB>2</SUB> reversibly in the solid state in a quantitative manner under clean and dry conditions at ambient temperature. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=b921688j'> </P>

Parabacteroides chongii sp. nov., isolated from blood of a patient with peritonitis

Kim, Hyunsoo,Im, Wan-Taek,Kim, Myungsook,Kim, Dokyun,Seo, Young Hee,Yong, Dongeun,Jeong, Seok Hoon,Lee, Kyungwon MICROBIOLOGICAL SOCIETY OF KOREA 2018 JOURNAL OF MICROBIOLOGY -SEOUL- Vol.56 No.10

Clinical Differences in Patients Infected with Fusobacterium and Antimicrobial Susceptibility of Fusobacterium Isolates Recovered at a Tertiary-Care Hospital in Korea

Kim Myungsook,Yun Shin Young,Lee Yunhee,Lee Hyukmin,Yong Dongeun,Lee Kyungwon 대한진단검사의학회 2022 Annals of Laboratory Medicine Vol.42 No.2

Background: Fusobacterium species are obligately anaerobic, gram-negative bacilli. Especially, F. nucleatum and F. necrophorum are highly relevant human pathogens. We investigated clinical differences in patients infected with Fusobacterium spp. and determined the antimicrobial susceptibility of Fusobacterium isolates. Methods: We collected clinical data of 86 patients from whom Fusobacterium spp. were isolated from clinical specimens at a tertiary-care hospital in Korea between 2003 and 2020. In total, 76 non-duplicated Fusobacterium isolates were selected for antimicrobial susceptibility testing by the agar dilution method, according to the Clinical and Laboratory Standards Institute guidelines (M11-A9). Results: F. nucleatum was most frequently isolated from blood cultures and was associated with hematologic malignancy, whereas F. necrophorum was mostly prevalent in head and neck infections. Anti-anaerobic agents were more commonly used to treat F. nucleatum and F. varium infections than to treat F. necrophorum infections. We observed no significant difference in mortality between patients infected with these species. All F. nucleatum and F. necrophorum isolates were susceptible to the antimicrobial agents tested. F. varium was resistant to clindamycin (48%) and moxifloxacin (24%), and F. mortiferum was resistant to penicillin G (22%) and ceftriaxone (67%). β-Lactamase activity was not detected. Conclusions: Despite the clinical differences among patients with clinically important Fusobacterium infections, there was no significant difference in the mortality rates. Some Fusobacterium spp. were resistant to penicillin G, ceftriaxone, clindamycin, or moxifloxacin. This study may provide clinically relevant data for implementing empirical treatment against Fusobacterium infections.

On the Effective Use of ASR Programs in a College Class of English Phonetics and Phonology

Myungsook Kim 한국영어학학회 2006 영어학연구 Vol.- No.22

  This paper explores the possibility of applying Automatic Speech Recognition(ASR) program to a college class of English phonetics and phonology and its effective uses. Although phonetic and phonological acquisition can be more effectively approached by realistic practice, most Korean college students do not have any opportunity to practice what they learned in class. This paper tries to show the need to develop a more innovative and specific way to give students chances to practice actual pronunciation for segmental English sounds as well as supra-segmental features like stress, rhythm, and intonation. The paper presents a pilot study for designing a practical college course of English phonetics and phonology in which students are given an extra assignment to improve their English pronunciation in a computer program assisted environment, provided that multimedia-assisted English education is the best possibility among more practical courses in the field. Two ASR programs, one CD-Rom based and the other the Internet based, were introduced to the students and compared in their use in order to search for the more effective application of the program in college classes of English phonetics and phonology.

Update on the Taxonomy of Clinically Important Anaerobic Bacteria

Myungsook Kim 대한임상검사과학회 2022 대한임상검사과학회지(KJCLS) Vol.54 No.4

The taxonomy of bacteria in the field of clinical microbiology is in a state of constant flux. A large-scale revamping of the classification and nomenclature of anaerobic bacteria has taken place over the past few decades, mainly due to advances in molecular techniques such as 16S rRNA and whole genome sequencing (WGS). New genera and species have been added, and existing genera and species have been reclassified or renamed. A major role of the clinical microbiological laboratories (CMLs) is the accurate identification (ID) and appropriate antimicrobial susceptibility testing (AST) for clinically important bacteria, and rapid reporting and communication of the same to the clinician. Taxonomic changes in anaerobic bacteria could potentially affect the choice of appropriate antimicrobial agents and the antimicrobial breakpoints to use. Furthermore, current taxonomy is important to prevent treatment failures of emerging pathogenic anaerobes with antimicrobial resistance. Therefore, CMLs should periodically update themselves on the changes in the taxonomy of anaerobic bacteria and suitably inform clinicians of these changes for optimum patient care. This article presents an update on the taxonomy of clinically important anaerobic bacteria, together with the previous names or synonyms. This taxonomy update can help guide antimicrobial therapy for anaerobic bacterial infections and prevent treatment failure and can be a useful tool for both CMLs and clinicians.

S-2 : Antimicrobial Resistance Trends in Korea

( Myungsook Kim ) 대한임상병리사협회 2009 임상미생물검사학회 발표자료집 Vol.2009 No.-