A comparative study of ectoparasites occurrence between grass carp and silver carp in guilan province culture ponds, Iran

( Mehrdad Asgharnia ),( Mohaddes Ghasemi ) 한국어병학회 2021 한국어병학회지 Vol.34 No.2

Parasitic infection is among the most common problems for carp cultivation. They are also important for the principal entrance of other hazardous infections as well. This study was carried out for determining of parasitic fauna of two major carp known as silver and grass carp with the comparison of prevalence value and intensity rate of parasites among them, alongside the relationship between the biometric characteristics and host sex with the infection level. For this purpose, a total of 94 fish samples were caught randomly using a fishing net, from Guilan ponds during spring and summer of the year 2018 and transported alive to the laboratory. Upon arriving, the biometric characteristics and genus of each carp were measured individually. Specimens were then acquired from the skin, gills, and eyes of the carp and examined according to standard parasitology methods. Recovered parasites were observed under a light microscope and then fixed for identification. As the result, the occurrence and intensity in the higher length group were comparatively greater than the lower one. Also, the prevalence and intensity of total parasites in male carp were higher than in females. In this research, Dactylogyrus hypophthalmichthys and Dactylogyrus aristhichtys were observed in silver carp and Dactylogyrus lamellatus was detected in grass carp. In the paper below, we found that the host specificity varies in different species of Dactylogyrus isolated from grass carp and silver carp.

Probing the Photoluminescence Characteristics and Dyeability of Dyed Luminous Polypropylene Fabric

Amin Ebrahimzade,Rouhollah Semnani Rahbar,Mohammad Reza Mohaddes Mojtahedi,Milad Valibeigi 한국섬유공학회 2019 Fibers and polymers Vol.20 No.12

Luminous polypropylene fibers were melt-spun using different amounts of phosphor strontium aluminate(SrAl2O4: Eu+2, Dy+3) as luminescent agent. The knitted fabrics were then prepared from these fibers and dyed with variousdisperse dyes, acid and basic dyes. Photoluminescence and dyeability properties of the fabrics were studied. According to thephotoluminescence spectroscopy results, a broad peak with a maximum at around 540 nm was observed for luminous fabricsafter exciting at the wavelength of 400 nm, indicating that luminescent particles were not destroyed or destructured duringmasterbatch preparation and melt spinning process. The dyeing performance of luminous PP fabrics was further evaluated bythe color strength (K/S values) and photographic images. Interesting improvement of the K/S values was observed for theluminous fabric dyed with acid dye. The results showed that the ionic charge of dye used and its molecular size could beaffected the afterglow intensity of dyed luminous fabrics. Although dyed luminous fabrics showed afterglow properties, theafterglow intensity diminished by enhancing the dyeability because of increased interference of dye molecules withluminescent particles. The color coordinates L*, a*, b*, c*, and ΔE specifications of dyed fabrics were marginally influenced inthe presence of luminescent particles.

The Polymorphism of Hypoxia-inducible Factor-1a Gene in Endometrial Cancer

Kafshdooz, Leila,Tabrizi, Ali Dastranj,Mohaddes, Seyyed Mojtaba,Kafshdooz, Tayebeh,Akbarzadeh, Abolfazl,Ghojazadeh, Morteza,Gharesouran, Jalal Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23

Background: Endometral carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in women after breast, colorectal and lung cancers Hypoxia-inducible factor-1 (HIF-1) is a key transcription factor that regulates cellular response to hypoxia HIF-1 plays important roles in the development and progression of cancer through activation of various genes that are involved in crucial aspects of cancer biology, including angiogenesis, energy metabolism, vasomotor function, erythropoiesis, and cell survival. In this study, we aimed to investigate the association between HIF-1 1772 C/T polymorphisms and endometrial cancer. Materials and Methods: 75 patients with endometrial carcinoma and 75 patients whose underwent hysterectomy for non tumoral indication selected for evaluation of HIF-1 1772 C/T polymorphisms by PCR-RFLP and sequencing. Results: For the 1772 C/T polymorphism, the analysis showed that the T allele and genotype TT were significantly associated with endometrial cancer risk. Conclusions: Our results suggest that the C1772T polymorphism of the HIF-1a may be associated with endometrial cancers.

C-kit Mutations in Endometrial Cancer: Correlation with Tumor Histologic Type

Kafshdooz, Taiebeh,Ardabili, Seyyed Mojtaba Mohaddes,Kafshdooz, Leila,Tabrizi, Ali Dastranj,Ghojazadeh, Morteza,Gharesouran, Jalal,Akbarzadeh, Abolfazl Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17

Objective: Endometrial cancer is the fourth most common cancer among women in developed countries. Affected patients may benefit from systemic chemotherapy, alone or in combination with targeted therapies if the disease is clinically diagnosed prior to expansion and metastasis to other organs. The aim of this study was to evaluate the prognostic role of c-kit mutations and comparision with tumor type and grade in human uterine endometrial carcinomas. Materials and Methods: Seventy five patients with endometrial carcinoma and seventy five normal controls were studied for possible mutations in exon 17 of the c-kit gene using single strand conformational polymorphisms and sequencing. Results: c-kit mutation in exon 17 appeared to be significantly different between endometrial carcinoma and normal endometrium. The pattern and frequency of the mutations was also shown to be different between tumors from different stages.

Effect of Education on Promoting Healthy Lifestyle Behaviors That Prevent Breast Cancer in Middle-Aged Women: Application of Protection Motivation Theory

Zakieh Sadat Hoseini,Hamid Tavakoli Ghouchani,Hamidreza Mohaddes Hakak,Hossein Lashkardoost,Ali Mehri,Mehdi Khankolabi,Elahe Salari 대한가정의학회 2021 Korean Journal of Family Medicine Vol.42 No.2

Background: In recent years, an increased incidence of breast cancer has made this disease the most common malignancy among Iranian women. Since education plays an important role in the implementation of preventive behaviors in breast cancer treatment, this study investigates the effect of educational interventions on the promotion of lifestyle-related behaviors that prevent breast cancer in middle-aged women. Methods: In this randomized control study, 120 women referred to Neyshabur Health Services Centers were randomly selected and divided into two groups: an intervention group (60 subjects) and a control group (60 subjects). An educational intervention was carried out over five sessions, based on protective motivation theory constructs. Participants completed a researcher-designed questionnaire immediately and again 2 months after the intervention. The data were analyzed using IBM SPSS ver. 19.0 software (IBM Corp., Armonk, NY, USA). Results: The results revealed a significant difference between the mean scores of participants exposed to protective motivation theory, awareness, and physical activities immediately and also 2 months after the intervention (P<0.05). Although the healthy diet scores of the two groups differed significantly immediately after the educational intervention (P<0.05), there was no significant difference between the groups 2 months after the intervention (P<0.05). Conclusion: Given the effective role of education in protective motivation theory and the physical activity levels of the women who participated in this research, it seems clear that the women’s financial status shaped their ability to consume more fruits and vegetables. As this social element impacts the health of individuals, training programs alone cannot succeed.

Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients

Mohammad Mehdi Akbarin,Abbas Shirdel,Alireza Bari,Seyedeh Tahereh Mohaddes,Houshang Rafatpanah,Ehsan Ghayour Karimani,Kobra Etminani,Amin Golabpour,Reza Torshizi 대한혈액학회 2017 Blood Research Vol.51 No.2

Background: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prog-nosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1). The HTLV-1 biomarkers trans-activator x (TAX) and HTLV-1 basic leucine zipper factor (HBZ) are main oncogenes and life-threatening elements. This study aimed to assess the role of the TAX and HBZ genes and HTLV-1 proviral load (PVL) in the survival of patients with ATLL. Methods: Forty-three HTLV-1-infected individuals, including 18 asymptomatic carriers (AC) and 25 ATLL patients (ATLL), were evaluated between 2011 and 2015. The mRNA expression of TAX and HBZ and the HTLV-1 PVL were measured by quantitative PCR. Results: Significant differences in the mean expression levels of TAX and HBZ were observed be-tween the two study groups (ATLL and AC, P=0.014 and P=0.000, respectively). In addi-tion, the ATLL group showed a significantly higher PVL than AC (P=0.000). There was a significant negative relationship between PVL and survival among all study groups (P=0.047). Conclusion: The HTLV-1 PVL and expression of TAX and HBZ were higher in the ATLL group than in the AC group. Moreover, a higher PVL was associated with shorter survival time among all ATLL subjects. Therefore, measurement of PVL, TAX, and HBZ may be beneficial for monitoring and predicting HTLV-1-infection outcomes, and PVL may be useful for prog-nosis assessment of ATLL patients. This research demonstrates the possible correlation between these virological markers and survival in ATLL patients.

Lack of Influence of TP53 Arg72Pro and 16bp Duplication Polymorphisms on Risk of Breast Cancer in Iran

Gohari-Lasaki, Sahar,Gharesouran, Jalal,Ghojazadeh, Morteza,Montazeri, Vahid,Ardebili, Seiied Moitaba Mohaddes Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.7

TP53 is assumed to be a very important tumour suppressor gene, as illustrated by recent reports that have shown effects of its polymorphisms on breast cancer risk. Arg72Pro and PIN3(16bp duplication) polymorphisms are proposed to have an effective role in structural changes of p53 and have therefore attracted interest as a risk factor for breast cancer in different populations. The aim of this study was to examine and determine whether p53 codon 72 and PIN3 Ins16 bp may be associated with an increased risk for breast cancer in female patients from the northwest of Iran. Genotyping was performed by PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism) method for a total of 100 women with breast cancer and 100 healthy women without any background of cancer, focusing on the TP53 Arg72Pro-16Del/Ins haplotypes and the combined genotypes. The results in this study established no statistical significant distinctions between the genotypes and a llele frequency were found for Arg72Pro and PIN3 Ins 16 bp polymorphisms between patients and controls.

Evaluation of the role of TAX, HBZ, and HTLV-1 proviral load on the survival of ATLL patients

Mohammad Mehdi Akbarin,Abbas Shirdel,Alireza Bari,Seyedeh Tahereh Mohaddes,Houshang Rafatpanah,Ehsan Ghayour Karimani,Kobra Etminani,Amin Golabpour,Reza Torshizi 대한혈액학회 2017 Blood Research Vol.52 No.2

Background: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy with very poor prog-nosis and short survival, caused by the human T-lymphotropic virus type-1 (HTLV-1). The HTLV-1 biomarkers trans-activator x (TAX) and HTLV-1 basic leucine zipper factor (HBZ) are main oncogenes and life-threatening elements. This study aimed to assess the role of the TAX and HBZ genes and HTLV-1 proviral load (PVL) in the survival of patients with ATLL. Methods: Forty-three HTLV-1-infected individuals, including 18 asymptomatic carriers (AC) and 25 ATLL patients (ATLL), were evaluated between 2011 and 2015. The mRNA expression of TAX and HBZ and the HTLV-1 PVL were measured by quantitative PCR. Results: Significant differences in the mean expression levels of TAX and HBZ were observed be-tween the two study groups (ATLL and AC, P=0.014 and P=0.000, respectively). In addi-tion, the ATLL group showed a significantly higher PVL than AC (P=0.000). There was a significant negative relationship between PVL and survival among all study groups (P=0.047). Conclusion: The HTLV-1 PVL and expression of TAX and HBZ were higher in the ATLL group than in the AC group. Moreover, a higher PVL was associated with shorter survival time among all ATLL subjects. Therefore, measurement of PVL, TAX, and HBZ may be beneficial for monitoring and predicting HTLV-1-infection outcomes, and PVL may be useful for prog-nosis assessment of ATLL patients. This research demonstrates the possible correlation between these virological markers and survival in ATLL patients.

Role of exon 7 PTEN Gene in Endometrial Carcinoma

Kafshdooz, Leila,Kafshdooz, Taiebeh,Tabrizi, Ali Dastranj,Ardabili, Seyyed Mojtaba Mohaddes,Akbarzadeh, Abolfazl,Gharesouran, Jalal,Ghojazadeh, Morteza,Farajnia, Safar Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

Background: Endometrial carcinoma is the most common malignant tumor of the female genital tract and the fourth most common cancer in Iranian women after breast, colorectal and lung cancers. Various genetic alterations appear to be early events in the pathogenesis of endometrial carcinoma and it seems that PTEN is the most commonly mutated gene in the endometrioid subtype. The aim of the present study was to investigate the correlation between mutations in exon 7 of PTEN gene and endometrial carcinoma. Materials and Methods: Seventy-five patients with endometrial carcinoma and 75 females whose underwent hysterectomy for non tumoral indication were selected for evaluation of PTEN mutations in exon 7 by PCR-SSCP and sequencing. Correlations between the frequency and type of mutation and the pathologic findings of the cancer (tumor subtype, stage and grade) were assessed. Results: All of the samples were obtained from Iranian patients. 60 % (45 cases) of the tumors were endometriod and 40% (30 cases) were of serous type. The grade distributions of the 75 cases according to the FIGO staging system were as follows: low grade, 20 cases; high grade 55 cases, low stage, 41 cases; high stage 34 cases. For exon 7 of the PTEN gene, the analysis showed that there were no mutations in our cases. Conclusions: Our findings in the present study suggest that exon 7 of PTEN does not play any significant role in the development of endometrial carcinoma in Iranian cases.

Polymorphism of p53 Gene Codon 72 in Endometrial Cancer: Correlation with Tumor Grade and Histological Type

Kafshdooz, Taiebeh,Tabrizi, Ali Dastranj,Ardabili, Seyyed Mojtaba Mohaddes,Kafshdooz, Leila,Ghojazadeh, Morteza,Gharesouran, Jalal,Abdii, Ali,Alizadeh, Hamideh Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: Endometrial cancer is the fourth most common cancer among women in developed countries. Patients with endometrial cancer may benefit from systemic chemotherapy alone or in combination with targeted therapies if the disease is clinically diagnosed prior to spread and metastasis to other organs. The aim of this study was to evaluate the prognostic role of p53 polymorphism and its correlation with tumor grade in human uterine endometrial carcinomas. Materials and Methods: A total of 75 patients with endometrial carcinomas were studied for possible mutations in exon 4 of the p53 gene using polymerase chain reaction and restricting fragment length polymorphism techniques and sequencing. Results: In recent study, The rate of homozygote genotype of pro/pro or Arg/Arg in high grade group was higher than in comparison with low grade one. In addition samples that were undigested in RFLP, showed mutation in exone 4. Conclusions: Our findings showed that high grade endometrial carcinomas are highly associated with TP53 polymorphisms in comparison with low grades.