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Xin Zhang,Minghao Fan,Yongkai Yuan,Jianjun Dong,Hua Yin,Yang He,Lei Mao,Dongfeng Wang,Junhong Yu 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.114 No.-
Fucoxanthin (FX) is a carotenoid with antioxidant, anti-obesity, anti-diabetic, anti-cancer and antibacterialactivities. It is poorly water soluble and highly sensitive to light, heat and the surrounding environment. Therefore, how to effectively encapsulate it and stabilize it for entry into the human body hasbecome a key research question at present. This study developed a single-carrier to encapsulate FX andshowed excellent characterization results. The experimental results showed that the diameters of FX-ZHparticles prepared by the four encapsulation processes ranged from 143.83 to 216.93 nm. Comparison ofantioxidant activity and stability to temperature and pH of the four complexes showed significant differences,with the best performance of the nanoparticles prepared using water-soluble method and a slowspeedstirrer. The nanocomplexes were proved to be more stable and more bioavailable, with a significant34.41% increase in FX content relative to free FX in the intestinal phase. Inhibition of human leukaemiacells HL-60 cells remained high, with 11.14% ± 6.03% inhibition at FX concentrations of 1 lg/mL. Thisstudy encapsulated FX based on colloidal nanoparticle systems for the first time using a single-carriermaterial, an innovation and breakthrough that could simplify the experimental steps and provide thenecessary basis for industrial realization.
중국의 산업집적과 경제성장 간 순환누적 효과에 관한 연구 ― 2007-2018년 현급 패널 데이터를 중심으로
호세전 ( Hu Shiqian ),범자충 ( Fan Zichong ),황명호 ( Huang Minghao ) 고려대학교 중국학연구소 2020 中國學論叢 Vol.0 No.70
In this paper, we take the mutual influences between the secondary industry agglomeration and economic growth in China’s county level as the research object. The panel data simultaneous equations models are specified to analyze the existence and change characteristics of the cyclical cumulative effects of industrial agglomeration and economic growth. The results show that industrial agglomeration and economic growth not only have a significant two-way relationship, but also they achieve their own cyclical cumulative effect based on the paths of “industrial agglomeration-economic growth-industrial agglomeration” and “economic growth-industrial agglomeration-economic growth” respectively. In terms of dynamics, compared to 2007~2013, the cumulative effect of agglomeration under the periodic impact of industrial agglomeration in 2014~2018 is weakened. The increasing diffusion effect leads to the decline of the role of industrial agglomeration in the economic growth cycle accumulation. In addition, the cumulative effects of different regions show heterogeneity characteristics. The cyclical cumulative effects of industrial agglomeration and economic growth are more significant in underdeveloped counties. In some economically developed counties, however, the industry isomorphism and the demand for the upgrading of industrial structure make the cumulative effect of industrial agglomeration become weak, and the crowding effect also makes the cumulative effect of economic growth decrease.