Analysis and Expression of the RIPs Gene in Wild Bitter Melon (Momordica charantia L. var. abbreviate Ser.)

Ming-Ya Huang,Man-Wai Liu,Tsu-Tsuen Wang,Wen-Ju Yang 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

Association of Family History with Cancer Recurrence and Survival in Patients with Hepatitis B-Related Hepatocellular Carcinoma (A Propensity Score Matching Analysis)

( Ju-dong Li ),( Xin-fei Xu ),( Jiong-jie Yu ),( Zhen-li Li ),( Hao Xing ),( Han Wu ),( Han Zhang ),( Chao Li ),( Ming-da Wang ),( Meng-chao Wu ),( Wan-yee Lau ),( Tian Yang ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: A family history of liver cancer is regarded as a risk factor for hepatocellular carcinoma (HCC) development. We investigated the association between family history and cancer recurrence and survival in patients with hepatitis B virus (HBV)- related HCC. Methods: Patients who underwent curative resection of HBV-related HCC between 2003 and 2013 from a tertiary hepatobiliary center in China were enrolled in this study. A family history was defined as a self-reported history of primary liver cancer in the first-degree relatives. Propensity score matching (PSM) and multivariable Cox-regression analyses were performed to compare the overall survival (OS) and recurrence-free survival (RFS) between patients with and without a family history of liver cancer. Results: Of 1,112 patients, 183 patients (16.5%) had a family history of liver cancer. A family history was not associated with OS and RFS (P=0.994 and 0.428) in the entire cohort. Using PSM, 179 pairs of patients with and without a family history but with comparable baseline characteristics and operative variables were created. A family history was associated with decreased OS and RFS (P=0.042 and 0.006) in the PSM cohort. On multivariable Cox-regression analyses, a family history was significantly associated with decreased OS (HR: 1.574, 95% CI: 1.171-2.116, P=0.003) and RFS (HR: 1.534, 95% CI: 1.176-2.002, P=0.002) after adjusting for other prognostic factors. Conclusions: A family history of liver cancer was associated with decreased OS and RFS rates after curative resection in patients with HBV-related HCC.

Interacting Multiview Tracker

Ju Hong Yoon,Ming-Hsuan Yang,Kuk-Jin Yoon IEEE 2016 IEEE transactions on pattern analysis and machine Vol.38 No.5

<P>A robust algorithm is proposed for tracking a target object in dynamic conditions including motion blurs, illumination changes, pose variations, and occlusions. To cope with these challenging factors, multiple trackers based on different feature representations are integrated within a probabilistic framework. Each view of the proposed multiview (multi-channel) feature learning algorithm is concerned with one particular feature representation of a target object from which a tracker is developed with different levels of reliability. With the multiple trackers, the proposed algorithm exploits tracker interaction and selection for robust tracking performance. In the tracker interaction, a transition probability matrix is used to estimate dependencies between trackers. Multiple trackers communicate with each other by sharing information of sample distributions. The tracker selection process determines the most reliable tracker with the highest probability. To account for object appearance changes, the transition probability matrix and tracker probability are updated in a recursive Bayesian framework by reflecting the tracker reliability measured by a robust tracker likelihood function that learns to account for both transient and stable appearance changes. Experimental results on benchmark datasets demonstrate that the proposed interacting multiview algorithm performs robustly and favorably against state-of-the-art methods in terms of several quantitative metrics.</P>

Fine control of titania deposition to prepare C@TiO₂ composites and TiO₂ hollow particles for photocatalysis and lithium-ion battery applications

Ming, Jun,Wu, Yingqiang,Nagarajan, Srinivasan,Lee, Dong-Ju,Sun, Yang-Kook,Zhao, Fengyu The Royal Society of Chemistry 2012 Journal of materials chemistry Vol.22 No.41

<P>In this study, an effective method of slow hydrolization of metal alkoxide (<I>e.g.</I>, Ti(C<SUB>4</SUB>H<SUB>9</SUB>O)<SUB>4</SUB>) in an ethanol–water system was systematically investigated and used to finely control the deposition of titania on carbon colloids. A model of adsorption–hydrolization of precursors during the coating process was rationally built for the first time to interpret the usability of the method and facilitate its further extension. Using this strategy, titania in the form of supported nanocrystals or layers on carbon colloids (TiO<SUB>2</SUB>/C, C@TiO<SUB>2</SUB>) was successfully tailored. Meanwhile, finely dispersed hollow TiO<SUB>2</SUB> nanoparticles with shells consisting of different crystalline structures were also prepared by varying the calcination conditions after removing the carbon cores. More importantly, the effects of the crystalline and nano/macrostructures of the as-prepared TiO<SUB>2</SUB> samples in photocatalysis and lithium-ion battery applications were analyzed in detail. The preliminary results show that anatase–rutile TiO<SUB>2</SUB> hollow particles demonstrate a higher catalytic activity in the photo-degradation of rhodamine B than anatase TiO<SUB>2</SUB> hollow particles, powders, and P25. However, in the case of Li-ion battery applications, the anatase TiO<SUB>2</SUB> hollow particles exhibited better performance as anode materials with high capacities of around 190 mA h g<SUP>−1</SUP>, 140 mA h g<SUP>−1</SUP>, and 120 mA h g<SUP>−1</SUP> at current densities of 60 mA g<SUP>−1</SUP>, 120 mA g<SUP>−1</SUP>, and 300 mA g<SUP>−1</SUP>, respectively, accompanied by stable cyclability.</P> <P>Graphic Abstract</P><P>Fine control of the titania deposition to prepare C@TiO<SUB>2</SUB> composites and TiO<SUB>2</SUB> hollow particles for photocatalysis and lithium-ion battery applications. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2jm34106a'> </P>

Highly Oriented Monolayer Graphene Grown on a Cu/Ni(111) Alloy Foil

Huang, Ming,Biswal, Mandakini,Park, Hyo Ju,Jin, Sunghwan,Qu, Deshun,Hong, Seokmo,Zhu, Zhili,Qiu, Lu,Luo, Da,Liu, Xiaochi,Yang, Zheng,Liu, Zhongliu,Huang, Yuan,Lim, Hyunseob,Yoo, Won Jong,Ding, Feng,Wa American Chemical Society 2018 ACS NANO Vol.12 No.6

<P>Fast-growth of single crystal monolayer graphene by CVD using methane and hydrogen has been achieved on “homemade” single crystal Cu/Ni(111) alloy foils over large area. Full coverage was achieved in 5 min or less for a particular range of composition (1.3 at.% to 8.6 at.% Ni), as compared to 60 min for a pure Cu(111) foil under identical growth conditions. These are the bulk atomic percentages of Ni, as a superstructure at the surface of these foils with stoichiometry Cu<SUB>6</SUB>Ni<SUB>1</SUB> (for 1.3 to 7.8 bulk at.% Ni in the Cu/Ni(111) foil) was discovered by low energy electron diffraction (LEED). Complete large area monolayer graphene films are either single crystal or close to single crystal, and include folded regions that are essentially parallel and that were likely wrinkles that “fell over” to bind to the surface; these folds are separated by large, wrinkle-free regions. The folds occur due to the buildup of interfacial compressive stress (and its release) during cooling of the foils from 1075 °C to room temperature. The fold heights measured by atomic force microscopy (AFM) and scanning tunneling microscopy (STM) prove them to all be 3 layers thick, and scanning electron microscopy (SEM) imaging shows them to be around 10 to 300 nm wide and separated by roughly 20 μm. These folds are always essentially perpendicular to the steps in this Cu/Ni(111) substrate. Joining of well-aligned graphene islands (in growths that were terminated prior to full film coverage) was investigated with high magnification SEM and aberration-corrected high-resolution transmission electron microscopy (TEM) as well as AFM, STM, and optical microscopy. These methods show that many of the “join regions” have folds, and these arise from interfacial adhesion mechanics (they are due to the buildup of compressive stress during cool-down, but these folds are different than for the continuous graphene films-they occur due to “weak links” in terms of the interface mechanics). Such Cu/Ni(111) alloy foils are promising substrates for the large-scale synthesis of single-crystal graphene film.</P> [FIG OMISSION]</BR>

Efficacy and Safety of Bevacizumab in Chinese Patients with Metastatic Colorectal Cancer

Zhu, Li-Ming,Zhao, Ya-Zhen,Ju, Hai-Xing,Liu, Lu-Ying,Chen, Lei,Liu, Bi-Xia,Xu, Qi,Luo, Cong,Ying, Jie-Er,Yang, Yun-Shan,Zhong, Hai-Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.16

Objective: To evaluate the efficacy and safety of bevacizumab in the treatment of patients with metastatic colorectal cancer (mCRC). Methods: In a single-center, observational study of 91 Chinese patients with mCRC who received bevacizumab in combination with chemotherapy was conducted. Objective response rates (ORRs), progression-free survival (PFS), overall survival (OS) and adverse events were recorded, and the relationships between various clinical factors and PFS or OS were evaluated by Cox proportional hazards models. Results: Treatment with bevacizumab and chemotherapy was effective and tolerable. Univariate analysis showed that PFS and OS were significantly associated with the Eastern Cooperative Oncology Group performance status (ECOG-PS) score, duration of bevacizumab exposure, and whether chemotherapy was continued after discontinuation of bevacizumab treatment. A multivariate analysis showed that the duration of bevacizumab exposure and whether chemotherapy was continued after discontinuation of bevacizumab were independent prognostic factors for PFS and OS. Conclusion: In Chinese mCRC population, the shorter the duration of exposure to bevacizumab and chemotherapy, the worse the prognosis is.

Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand

Li, Rong,Ju, Ming-Yang,Chen, Bin,Sun, Qing-Yuan,Chen, Guo-Liang,Shi, Mei,Wang, Xiao-Gang,Zheng, Jian-Bin Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.2

An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.

Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand

Rong Li,Ming-Yang Ju,Bin Chen,Qing-Yuan Sun,Guo-Liang Chen,Mei Shi,Xiao-Gang Wang,Jian-Bin Zheng 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.2

An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.

Prevention of Natural Flowering in Pineapple (Ananas comosus) by Shading and Urea Application

Meng-Tzu Lin,Alfred Ming Chen1,Tzong-Shyan Lin,Ching-San Kuan,Ching-Lung Lee,Wen-Ju Yang 한국원예학회 2015 Horticulture, Environment, and Biotechnology Vol.56 No.1

The year-round production of pineapple (Ananas comosus var. comosus) is often interrupted by natural flowering during winter in Taiwan. A stable and promising technique for preventing natural flowering is required. In this study, we have tested the effect of shading and urea application on the flowering of pineapple. Shading 90% of sun light(s) before mid-November delayed the natural flowering of pineapple and the delay was affected by the plant age. For pineapples planted less than 11 month before mid-November, applying 1% urea plus shading treatment (SN) completely inhibited natural flowering. All the flowering-inhibited plants could be forced to flower by applying calcium carbide. Long-term shading might result in a decreased number of fruitlets within a fruit. However, 6 weeks of recovery before forcing flowering was sufficient for plants to produce fruits with quality equal to that of the control plants. In winter, pineapple plants that were prone to flowering tended to accumulate more leaf starch and increase their C/N ratio. The SN treatment increased the leaf nitrogen concentration and thus effectively maintained a low leaf C/N ratio. Furthermore, flowering-inhibited plants exhibited a constantly low level of leaf starch during the winter and their flowering forced by calcium carbide did not accompany with leaf starch accumulation.

Vitamin D3 and Beta-carotene Deficiency is Associated with Risk of Esophageal Squamous Cell Carcinoma - Results of a Case-control Study in China

Huang, Gui-Ling,Yang, Lei,Su, Ming,Wang, Shao-Kang,Yin, Hong,Wang, Jia-Sheng,Sun, Gui-Ju Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Objective: The aim was to evaluate roles of vitamin D3 (VD3) and beta-carotene (BC) in the development of esophageal squamous cell carcinoma (ESCC) in a high-risk area, Huai'an District, Huai'an City, China. Methods: 100 new ESCC diagnosed cases from 2007 to 2008 and 200 residency- age-, and sex-matched healthy controls were recruited. Data were collected from questionnaires, including a food frequency questionnaire (FFQ) to calculate the BC intake, and reversed phase high-performance liquid chromatography (RP-HPLC) was used to measure the serum concentrations of BC and VD3. Odds ratios (OR) and 95% confidence intervals (CI) were calculated in conditional logistic regression models. Results: The average dietary intake of BC was $3322.9{\mu}g$ (2032.4-5734.3) in the case group and $3626.8{\mu}g$ (1961.9-5827.9) in control group per capita per day with no significant difference by Wilcoxon test (p>0.05). However, the levels of VD3 and BC in the case group were significantly lower than in the control group (p<0.05). The OR values of the highest quartile and the lowest quartile of VD3 and BC in serum samples were both 0.13. Conclusion: Our results add to the evidence that high circulating levels of VD3 and BC are associated with a reduced risk of ESCC in this Chinese population.