http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Karakus, Melike,Sung, Younghun,Wang, Hai I.,Mics, Zoltá,n,Char, Kookheon,Bonn, Mischa,Cá,novas, Enrique American Chemical Society 2017 JOURNAL OF PHYSICAL CHEMISTRY C - Vol.121 No.24
<P>We investigate photoinduced carrier dynamics by time resolved terahertz spectroscopy (TRTS) in Pt nanoparticle decorated CdSe tetrapods as a function of Pt nanoparticles size (and identical areal density). We find that the collection efficiency of electrons photo generated in the tetrapods by the Pt particle increases as a function of Pt nanoparticle size. However, the photocatalytic H-2 generation efficiency is reduced for tetrapods decorated with larger Pt particles. Our results demonstrate a competition between electron capture efficiency at the semiconducting/metal interface, increasing with nanoparticles size, and electron release efficiency at the metal/water interface, decreasing with nanoparticles size. This trade-off defines an optimum for photocatalytic H-2 generation in Pt cocatalyst decorated CdSe tetrapods as a function of Pt size.</P>
MicroRNAs and periodontal disease: a qualitative systematic review of human studies
Pablo Micó-Martínez,Pedro J. Almiñana-Pastor,Francisco Alpiste-Illueca,Andrés López-Roldán 대한치주과학회 2021 Journal of Periodontal & Implant Science Vol.51 No.6
Purpose: MicroRNAs (miRNAs) are epigenetic post-transcriptional regulators that modulate gene expression and have been identified as biomarkers for several diseases, including cancer. This study aimed to systematically review the relationship between miRNAs and periodontal disease in humans, and to evaluate the potential of miRNAs as diagnostic and prognostic biomarkers of disease. Methods: The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (reference number CRD42020180683). The MEDLINE, Scopus, Cochrane Library, Embase, Web of Science, and SciELO databases were searched for clinical studies conducted in humans investigating periodontal diseases and miRNAs. Expression levels of miRNAs across the different groups were analysed using the collected data. Results: A total of 1,299 references were identified in the initial literature search, and 23 articles were finally included in the review. The study designs were heterogeneous, which prevented a meta-analysis of the data. Most of the studies compared miRNA expression levels between patients with periodontitis and healthy controls. The most widely researched miRNA in periodontal diseases was miR-146a. Most studies reported higher expression levels of miR-146a in patients with periodontitis than in healthy controls. In addition, many studies also focused on identifying target genes of the differentially expressed miRNAs that were significantly related to periodontal inflammation. Conclusions: The results of the studies that we analysed are promising, but diagnostic tests are needed to confirm the use of miRNAs as biomarkers to monitor and aid in the early diagnosis of periodontitis in clinical practice.
Stanislav Vajı´cˇek,Magdale´na Sˇtolcova´,Alexander Kaszonyi,Matej Micˇusˇı´k,Pavel Alexy c, Patrizia Canton,Patrizia Canton,Gyo¨ rgy Onyestya´k,Szabolcs Harnos,Ferenc Lo´ nyi,Jo´ zsef Valyon 한국공업화학회 2016 Journal of Industrial and Engineering Chemistry Vol.39 No.-
Palladium-bismuth nanoparticles were supported into strongly basic anion-exchange resin of gel-typeand tested as catalysts for the selective oxidation of glycerol with molecular oxygen at atmosphericpressure. Detailed study of the precursors preparation and reduction were undertaken. The catalyst3%Pd-1%Bi where the bismuth was deposited on the palladium particles (3.4 nm) exhibited at 95%glycerol conversion more than 63% yield toward glyceric acid and tartronic acid after 3 h of reaction. Thecatalyst maintains practically similar catalytic performance as in fresh state for at least five consecutivecatalytic cycles without extra catalyst treatment and reactivation.
Katarina R. Savic´ Vujovic,Sonja Vucˇkovic,Dragana Srebro,Milovan Ivanovic,Ljiljana Dosˇen-Mic´ovic,C ˇ edomir Vucˇetic,Eleonora Dzˇoljic,Milica Prostran 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.4
In addition to producing antinociception, opioidsexert profound effects on body temperature. This studyaimed at comparing antinociceptive and hyperthermicresponses between two groups of l-opioid receptor agonists:fentanyl (4-anilinopiperidine-type) and morphine(phenanthrene-type) derivatives in rats. Analgesic activitywas assessed by tail immersion test and the body temperatureby insertion of a thermometer probe into the colon. Fentanyl (F), (±)-cis-3-methyl fentanyl (CM), (±)-cis-3-carbomethoxy fentanyl (C), (±)trans-3-carbomethoxyfentanyl (T) and (±)-cis-3 butyl fentanyl (B) produceddose-dependent increase in antinociception and hyperthermia. The relative order of analgesic potency was:CM(11.27)[F(1)[C(0.35)CT(0.11)CB(0.056). Similar tothis, the relative order of hyperthermic potency was:CM(8.43)[F(1)[C(0.46)CT(0.11)CB(0.076). Morphine(M), oxycodone (O), thebacon (T) and 6,14-ethenomorphinan-7-methanol, 4,5-epoxy-6-fluoro-3-hydroxy-a,a,17-trimethyl-, (5a,7a) (E) also produced dose-dependentincrease in antinociception and hyperthermia. Amongmorphine derivatives the relative order of analgesicpotency was: E(56)[O(5)CT(2.6)[M(1), and similar tothis, the relative order of hyperthermic potency was:E(37)[O(3)CT(2.3)[M(1). Morphine (phenanthrene-type)and fentanyl (4-anilinopiperidine-type) derivatives producedhyperthermia in rats at doses about 2 times lower,and 6–11 times higher, than their median antinociceptivedoses, respectively. This study is first to identify differencebetween these two classes of opioid drugs in their potenciesin producing hyperthermia. Further studies are needed toclarify the significance of these findings.
A unified analysis of four cosmic shear surveys
Chang, Chihway,Wang, Michael,Dodelson, Scott,Eifler, Tim,Heymans, Catherine,Jarvis, Michael,Jee, M James,Joudaki, Shahab,Krause, Elisabeth,Malz, Alex,Mandelbaum, Rachel,Mohammed, Irshad,Schneider, Mic Oxford University Press 2019 Monthly notices of the Royal Astronomical Society Vol.482 No.3
Lin, Jia,Chen, Hong,Gao, Yang,Cai, Yao,Jin, Jianbo,Etman, Ahmed S.,Kang, Joohoon,Lei, Teng,Lin, Zhenni,Folgueras, Maria C.,Quan, Li Na,Kong, Qiao,Sherburne, Matthew,Asta, Mark,Sun, Junliang,Toney, Mic National Academy of Sciences 2019 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.116 No.47
<P><B>Significance</B></P><P>Metal halide perovskites attract great interest for a wide range of applications due to their remarkable optoelectronic properties. The development of environmentally friendly halide perovskite materials with various crystal structures and compositions offers unprecedented opportunities to achieve desired properties and applications. In this work, we demonstrated an In-based, charge-ordered all-inorganic halide double perovskite with the composition of Cs<SUB>2</SUB>In(I)In(III)Cl<SUB>6</SUB> synthesized by solid-state reaction. High-pressure optical properties were studied, and a pressure-driven, fully reversible semiconductor–metal phase transition was discovered. This In-based charge-ordered structure may inspire new understanding of halide perovskite as well as provide a platform for future discovery of exotic electronic phenomena such as high-<I>T</I><SUB>C</SUB> superconductivity in halide perovskite compounds.</P><P>Phase transitions in halide perovskites triggered by external stimuli generate significantly different material properties, providing a great opportunity for broad applications. Here, we demonstrate an In-based, charge-ordered (In<SUP>+</SUP>/In<SUP>3+</SUP>) inorganic halide perovskite with the composition of Cs<SUB>2</SUB>In(I)In(III)Cl<SUB>6</SUB> in which a pressure-driven semiconductor-to-metal phase transition exists. The single crystals, synthesized via a solid-state reaction method, crystallize in a distorted perovskite structure with space group <I>I</I>4/<I>m</I> with <I>a</I> = 17.2604(12) Å, <I>c</I> = 11.0113(16) Å if both the strong reflections and superstructures are considered. The supercell was further confirmed by rotation electron diffraction measurement. The pressure-induced semiconductor-to-metal phase transition was demonstrated by high-pressure Raman and absorbance spectroscopies and was consistent with theoretical modeling. This type of charge-ordered inorganic halide perovskite with a pressure-induced semiconductor-to-metal phase transition may inspire a range of potential applications.</P>
AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell Survival
Fisher, Kurt W.,Das, Binita,Kim, Hyun Seok,Clymer, Beth K.,Gehring, Drew,Smith, Deandra R.,Costanzo-Garvey, Diane L.,Fernandez, Mario R.,Brattain, Michael G.,Kelly, David L.,MacMillan, John,White, Mic American Society for Microbiology 2015 Molecular and cellular biology Vol.35 No.22
<P>A major goal of cancer research is the identification of tumor-specific vulnerabilities that can be exploited for the development of therapies that are selectively toxic to the tumor. We show here that the transcriptional coactivators peroxisome proliferator-activated receptor gamma coactivator 1β (PGC1β) and estrogen-related receptor α (ERRα) are aberrantly expressed in human colon cell lines and tumors. With kinase suppressor of Ras 1 (KSR1) depletion as a reference standard, we used <U>fu</U>nctional <U>si</U>gnature <U>on</U>tology (FUSION) analysis to identify the γ1 subunit of AMP-activated protein kinase (AMPK) as an essential contributor to PGC1β expression and colon tumor cell survival. Subsequent analysis revealed that a subunit composition of AMPK (α2β2γ1) is preferred for colorectal cancer cell survival, at least in part, by stabilizing the tumor-specific expression of PGC1β. In contrast, PGC1β and ERRα are not detectable in nontransformed human colon epithelial cells, and depletion of the AMPKγ1 subunit has no effect on their viability. These data indicate that Ras oncogenesis relies on the aberrant activation of a PGC1β-dependent transcriptional pathway via a specific AMPK isoform.</P>