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      • Mode of reproduction of Barbarea vulgaris in two different habitats in Tohoku, Japan

        Tachibana, Masaaki,Itoh, Kazuyuki,Watanabe, Hiroaki,Nakayama, Soichi The Korean Society of Weed Science and The Turfgra 2010 Weed Biology and Management Vol.10 No.1

        This study was conducted to determine the reproductive characteristics of Barbarea vulgaris under different disturbance regimes (mowing and tilling) in two different habitats: a levee and a wheat field. On the levee, 77 of the 114 individuals that had had their floral stalks removed by the first mowing produced new rosettes at the basal part of the stem during the same growing season. The plants that were mowed four times per year had a significantly greater survival rate than the plants that were mowed twice per year. The levee population that was mowed without tillage was largely maintained by vegetative reproduction. These results suggest that mowing the levees promotes the vegetative reproduction of B. vulgaris and helps it to compete with tall-growing plants, thus facilitating its survival as a perennial. In spite of the high sprouting ability of the plant's root fragments, most of the root fragments did not regenerate when buried or when exposed to high soil moisture conditions in tilled wheat fields. The population of B. vulgaris in tilled wheat fields was maintained almost entirely by sexual reproduction. Barbarea vulgaris can survive under two different management regimes by altering its mode of reproduction.

      • KCI등재

        Temperature Dependence of the Photoluminescence Properties in ZnS-CdS Aloy Quantum Dots

        Shinya OKAHARA,DaeGwi Kim,Masaaki NAKAYAMA 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.1

        We have investigated the exciton dynamics in ZnS-CdS aloy quantum dots (QDs) prepared by using a coloidal method. A combination of a size-selective photoetching proces and a surface modification technique with a Cd(OH)₂ layer enables us to prepare size- and surface- controled QDs with a high photoluminescence (PL) effiiency. We found the temperature dependence of the PL decay profiles to be unusual; namely, the decay time becomes longer with increasing temperature. The temperature dependence of the decay time is wel described in termsofathre-levelmodelincludingatriplet-originexcitonstate,theso-caleddark-exciton state, the so-called dark-exciton state. We have investigated the exciton dynamics in ZnS-CdS aloy quantum dots (QDs) prepared by using a coloidal method. A combination of a size-selective photoetching proces and a surface modification technique with a Cd(OH)₂ layer enables us to prepare size- and surface- controled QDs with a high photoluminescence (PL) effiiency. We found the temperature dependence of the PL decay profiles to be unusual; namely, the decay time becomes longer with increasing temperature. The temperature dependence of the decay time is wel described in termsofathre-levelmodelincludingatriplet-originexcitonstate,theso-caleddark-exciton state, the so-called dark-exciton state.

      • KCI등재

        Fabrication of ZnO Hexagonal Micropyramids by Using an rf-Magnetron Sputtering Method

        Shingo Komura,DaeGwi Kim,Shuji Wakaiki,Masaaki Nakayama 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.53 No.1

        We report on fabrication of self-assembled ZnO hexagonal micropyramids grown on a (0001) Al2O3 substrate by using an rf-magnetron sputtering method from the aspects of thier structural and optical properties. We found that the average size of the hexagonal micropyramids increases with increasing growth temperature. The re ection and the photoluminescence spectra at 10 K demonstrate high-quality optical properties for the total growth layer. Especially, for the growth temperatures of 650 ℃ and 700 ℃, fine structures are observable in the excitonic transitions in the re ection spectra. Furthermore, under high-density excitation conditions, photoluminescence bands originating from bi-exciton formation and from an inelastic scattering process of excitons, the so-called P emission, were observed. We report on fabrication of self-assembled ZnO hexagonal micropyramids grown on a (0001) Al2O3 substrate by using an rf-magnetron sputtering method from the aspects of thier structural and optical properties. We found that the average size of the hexagonal micropyramids increases with increasing growth temperature. The re ection and the photoluminescence spectra at 10 K demonstrate high-quality optical properties for the total growth layer. Especially, for the growth temperatures of 650 ℃ and 700 ℃, fine structures are observable in the excitonic transitions in the re ection spectra. Furthermore, under high-density excitation conditions, photoluminescence bands originating from bi-exciton formation and from an inelastic scattering process of excitons, the so-called P emission, were observed.

      • KCI등재

        Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas

        Machino Hidenori,Dozen Ai,Konaka Mariko,Komatsu Masaaki,Nakamura Kohei,Ikawa Noriko,Shozu Kanto,Asada Ken,Kaneko Syuzo,Yoshida Hiroshi,Kato Tomoyasu,Nakayama Kentaro,Saloura Vassiliki,Kyo Satoru,Hamam 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        High-grade serous ovarian carcinoma (HGSOC) is the most lethal gynecological malignancy. To date, the profiles of gene mutations and copy number alterations in HGSOC have been well characterized. However, the patterns of epigenetic alterations and transcription factor dysregulation in HGSOC have not yet been fully elucidated. In this study, we performed integrative omics analyses of a series of stepwise HGSOC model cells originating from human fallopian tube secretory epithelial cells (HFTSECs) to investigate early epigenetic alterations in HGSOC tumorigenesis. Assay for transposase-accessible chromatin using sequencing (ATAC-seq), chromatin immunoprecipitation sequencing (ChIP-seq), and RNA sequencing (RNA-seq) methods were used to analyze HGSOC samples. Additionally, protein expression changes in target genes were confirmed using normal HFTSECs, serous tubal intraepithelial carcinomas (STICs), and HGSOC tissues. Transcription factor motif analysis revealed that the DNA-binding activity of the AP-1 complex and GATA family proteins was dysregulated during early tumorigenesis. The protein expression levels of JUN and FOSL2 were increased, and those of GATA6 and DAB2 were decreased in STIC lesions, which were associated with epithelial-mesenchymal transition (EMT) and proteasome downregulation. The genomic region around the FRA16D site, containing a cadherin cluster region, was epigenetically suppressed by oncogenic signaling. Proteasome inhibition caused the upregulation of chemokine genes, which may facilitate immune evasion during HGSOC tumorigenesis. Importantly, MEK inhibitor treatment reversed these oncogenic alterations, indicating its clinical effectiveness in a subgroup of patients with HGSOC. This result suggests that MEK inhibitor therapy may be an effective treatment option for chemotherapy-resistant HGSOC.

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