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Scaling analysis of magnetic-thermal behaviors in ferromagnetic insulator LaCoO3 thin film
Liu Hao,Fan Jiyu,Zheng Huan,Rahman Azizur,Qian Fengjiao,Wang Caixia,Ma Chunlan,Zhu Yan,Yang Hao 한국물리학회 2021 Current Applied Physics Vol.28 No.-
The structure, surface topography and magnetic properties of LaCoO3 (LCO) thin films deposited epitaxially on the SrTiO3 substrates have been investigated in detail. The LCO thin films show a typical ferromagneticparamagnetic (FM-PM) phase transition at 78 K. Based on the measurements of isothermal magnetization around the Curie point, the magnetic entropy change (ΔSM) of LCO thin films under various applied magnetic fields were obtained. By utilizing scaling theory, all of the ΔSM curves can be re-scaled, confirming that the FMPM phase transition is second-order magnetic phase transition. Moreover, the magnetic entropy change -ΔSM features a maximum around TC, whereas, power law fitting of -ΔSmax M with H gives n = 0.9704, which is obviously deviating from the standard value n = 2/3 for the Landau mean field model. This indicates that the mean field theory cannot be used to explain the critical behavior of LCO thin films which implies that the critical behavior of LCO thin films may involve complex magnetic interactions. These interactions are correlated with a long-term puzzling finding in this system why its Curie point is always around 80 K regardless of the different fabrication methods and conditions used in the film growth.
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Novel blood-based hypomethylation of SH3BP5 is associated with very early-stage lung adenocarcinoma
Qiao Rong,Zhong Runbo,Liu Chunlan,Di Feifei,Zhang Zheng,Wang Ling,Xu Tian,Wang Yue,Dai Liping,Gu Wanjian,Han Baohui,Yang Rongxi 한국유전학회 2022 Genes & Genomics Vol.44 No.4
Background: Early detection is essential to improve the survival of lung cancer (LC). The quantitative measurement of specific DNA methylation changes in the peripheral blood could provide an efficient strategy for the detection of early cancer. Objective: We applied a candidate approach and assess the association between blood-based SH3BP5 methylation and the risk of lung adenocarcinoma (LUAD) in a case-control cohort. Methods: The methylation level of four CpG sites in the promoter of SH3BP5 gene was quantitatively determined by mass spectrometry in 171 very early-stage LUAD patients (93.6% LUAD at stage I) and 190 age and gender-matched controls. The logistic regression and non-parametric tests were used for the statistical analyses. Results: We observed a significant association between decreased methylation of SH3BP5_CpG_4 in the peripheral blood and increased risk of LUAD (odds ratio (OR) per-10% methylation = 1.51, P = 0.006, FDR = 0.024), and even for the LUAD at stage I (OR per-10% methylation = 1.53, P = 0.006, FDR = 0.024). Moreover, the lower quartile of SH3BP5_CpG_4 methylation was correlated with increased risk for LUAD with a P trend of 0.011. Further investigation disclosed that the hypomethylation of SH3BP5_CpG_4 was mostly associated with LUAD in younger subjects (OR per-10% methylation = 2.02, P = 0.010, age < 55 years old) and probably could be enhanced by advance stage. Conclusion: Our study revealed an association between blood-based SH3BP5 hypomethylation and very early-stage LUAD, which provides a novel support for the blood-based methylation signatures as a potential marker for the evaluation of cancer risk.
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Industries TFP and Environmental Regulation Cost Analysis Using Malmquist Luenberger
Haiyan Wang,Liting Shen,Chunlan Liu,Hui Han 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.2
Environmental problem is a worldwide focus, so is the effect of environmental regulation on economy. In this paper, we constructed a model including energy consumption and integrated pollutant emissions of "Three wastes" as "bad" output. This studyr used Malmquist –Luenberger based on directional distance function to measure TFP and environmental regulation cost of Chinese 36 industries from 2001 to 2010. The result was that: From the overall analysis, the TFP was lower after considering the environmental regulation. Technological progress was the main driver of productivity growth. Environmental regulation brought about a certain cost; from the industry analysis, Difference of TFP growth and the cost of environmental regulation existed among different industries. The monopoly and heavy industries were the focus in the industry; from the annual analysis, TFP increased during "Eleventh Five-Year Plan" period, mainly drived by technological progress.
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Identification and Function Prediction of Novel MicroRNAs in Laoshan Dairy Goats
Ji, Zhibin,Wang, Guizhi,Zhang, Chunlan,Xie, Zhijing,Liu, Zhaohua,Wang, Jianmin Asian Australasian Association of Animal Productio 2013 Animal Bioscience Vol.26 No.3
MicroRNAs are a class of endogenous small RNAs that play important roles in post-transcriptional gene regulation by directing degradation of mRNAs or facilitating repression of target gene translation. In this study, three small RNA cDNA libraries from the mammary gland tissues of Laoshan dairy goats (Capra hircus) were constructed and sequenced, individually. Through Solexa high-throughput sequencing and bioinformatics analysis, we obtained 50 presumptive novel miRNAs candidates, and 55,448 putative target genes were predicted. GO annotations and KEGG pathway analyses showed the majority of target genes were involved in various biological processes and metabolic pathways. Our results discovered more information about the regulation network between miRNAs and mRNAs and paved a foundation for the molecular genetics of mammary gland development in goats.
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