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      • KCI등재

        중국기업의 지배구조가 대리인비용에 미치는 영향

        Zheng Lirong,최진현(Choi Jin-hyeon) 한국국제회계학회 2010 국제회계연구 Vol.0 No.29

        중국기업의 지배구조에 대한 정보는 우리나라 투자자들이 중국 증권시장에 직접투자 하거나 펀드 등을 통한 간접투자를 하는데 꼭 필요할 것이다. 이런 관점에서 본 연구는 중국 상하이 증권시장에서 지수를 결정짓는 180개 지수기업을 대상으로 4개 회계연도(2005-2008)의 데이터를 이용하여 지배구조가 대리인비용에 영향을 미치는지 검토 분석하였다. 첫째, 중국의 상장기업에서 사외이사가 이사회 내에서 견제 역할을 제대로 수행하지 못하고 있는 것으로 보인다. 둘째, 중국에서 경영자 인센티브(지분율)는 대리인비용을 낮추는데 유의한 상관관계가 없는 것으로 나타났다. 셋째, 중국 상장기업에서 대표이사가 이사회 회장을 겸임하지 않으면 자산회전율이 높아지고 대리인비용은 낮아지는 결과를 보이고 이사회 활동성이 높은 기업일수록 자산회전율이 상대적으로 높게 나타났다. 넷째, 소유구조 집중도가 높은 기업은 상대적으로 경영자의 기회주의행위를 억제하고 대리인비용을 감소시킬 수 있다 본 연구에서 분석의 대상이 된 상하이 지수기업의 수가 적어서 국유기업/ 비국유기업의 비교, 2006년 제정된 신회계준칙 적용 전후의 비교에서는 유의한 결과를 얻지 못했다. This study is focused on the findings of corporate governance elements which effect on the agency costs in Chinese enterprises. The processes of this empirical study are establishment of research hypotheses, elaboration of test model, definition and measurement of sample companies, empirical analysis and interpretation of results. The samples of this study are 180 firms registered on Shanghai Stock Exchange from 2005 to 2008 excluding financial and insurance business. The data used in this research are provided from SSEportal and SinoFin information service Co. in China. The proxies of corporate governance (dependent variables) are board independence, outside director. auditor council, ownership structure, and proxies of agency costs(independent variables) are sale and management expenses/operating revenues, operating revenues/total assets, operating revenues/other operating expenses, control variables are firm size, ratio of current liabilities/total assets, ratio of net cash inflow /total liabilities, dummy variable. The results of this study are as followings. First, the activity and independence of board takes positive effects on the agency costs, but size of board does not take effects on the agency costs in Chinese enterprises. Second, the size of auditor council takes negative effects on the agency costs in Chinese enterprises. Third, the concentration of ownership takes negative effects on the agency costs in Chinese enterprises.

      • KCI등재

        Whole transcriptome mapping reveals the lncRNA regulatory network of TFP5 treatment in diabetic nephropathy

        Luo Hongyan,Yang Lirong,Zhang Guoqing,Bao Xi,Ma Danna,Li Bo,Cao Li,Cao Shilu,Liu Shunyao,Bao Li,E Jing,Zheng Yali 한국유전학회 2024 Genes & Genomics Vol.46 No.5

        Background TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production. However, the role of TFP5 in diabetic nephropathy (DN) is still unclear. Objective This study aims to characterize the transcriptome profiles of mRNA and lncRNA in TFP5-treated DN mice to mine key lncRNAs associated with TFP5 efficacy. Methods We evaluated the role of TFP5 in DN pathology and performed RNA sequencing in C57BL/6J control mice, C57BL/6J db/db model mice, and TFP5 treatment C57BL/6J db/db model mice. The differentially expressed lncRNAs (DElncRNAs) and mRNAs (DEmRNAs) were analyzed. WGCNA was used to screen hub-gene of TFP5 in treatment of DN. Results Our results showed that TFP5 therapy ameliorated renal tubular injury in DN mice. In addition, compared with the control group, the expression profile of lncRNAs in the model group was significantly disordered, while TFP5 alleviated the abnormal expression of lncRNAs. A total of 67 DElncRNAs shared among the three groups, 39 DElncRNAs showed a trend of increasing in the DN group and decreasing after TFP treatment, while the remaining 28 showed the opposite trend. DElncRNAs were enriched in glycosphingolipid biosynthesis signaling pathways, NF-κB signaling pathways, and complement activation signaling pathways. There were 1028 up-regulated and 1117 down-regulated DEmRNAs in the model group compared to control group, and 123 up-regulated and 153 down-regulated DEmRNAs in the TFP5 group compared to the model group. The DEmRNAs were involved in PPAR and MAPK signaling pathway. We confirmed that MSTRG.28304.1 is a key DElncRNA for TFP5 treatment of DN. TFP5 ameliorated DN maybe by inhibiting MSTRG.28304.1 through regulating the insulin resistance and PPAR signaling pathway. The qRT-PCR results confirmed the reliability of the sequencing data through verifying the expression of ENSMUST00000211209, MSTRG.31814.5, MSTRG.28304.1, and MSTRG.45642.14. Conclusion Overall, the present study provides novel insights into molecular mechanisms of TFP5 treatment in DN. Background TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production. However, the role of TFP5 in diabetic nephropathy (DN) is still unclear. Objective This study aims to characterize the transcriptome profiles of mRNA and lncRNA in TFP5-treated DN mice to mine key lncRNAs associated with TFP5 efficacy. Methods We evaluated the role of TFP5 in DN pathology and performed RNA sequencing in C57BL/6J control mice, C57BL/6J db/db model mice, and TFP5 treatment C57BL/6J db/db model mice. The differentially expressed lncRNAs (DElncRNAs) and mRNAs (DEmRNAs) were analyzed. WGCNA was used to screen hub-gene of TFP5 in treatment of DN. Results Our results showed that TFP5 therapy ameliorated renal tubular injury in DN mice. In addition, compared with the control group, the expression profile of lncRNAs in the model group was significantly disordered, while TFP5 alleviated the abnormal expression of lncRNAs. A total of 67 DElncRNAs shared among the three groups, 39 DElncRNAs showed a trend of increasing in the DN group and decreasing after TFP treatment, while the remaining 28 showed the opposite trend. DElncRNAs were enriched in glycosphingolipid biosynthesis signaling pathways, NF-κB signaling pathways, and complement activation signaling pathways. There were 1028 up-regulated and 1117 down-regulated DEmRNAs in the model group compared to control group, and 123 up-regulated and 153 down-regulated DEmRNAs in the TFP5 group compared to the model group. The DEmRNAs were involved in PPAR and MAPK signaling pathway. We confirmed that MSTRG.28304.1 is a key DElncRNA for TFP5 treatment of DN. TFP5 ameliorated DN maybe by inhibiting MSTRG.28304.1 through regulating the insulin resistance and PPAR signaling pathway. The qRT-PCR results confirmed the reliability of the sequencing data through verifying the expression of ENSMUST00000211209, MSTRG.31814.5, MSTRG.28304.1, and MSTRG.45642.14. Conclusion Overall, the present study provides novel insights into molecular mechanisms of TFP5 treatment in DN.

      • KCI등재

        Improved Four-channel PBTDPA Control Strategy Using Force Feedback Bilateral Teleoperation System

        Xin Gong,Lixiao Wang,Yuanyuan Mou,Haili Wang,Xiaoqian Wei,Wenfeng Zheng,Lirong Yin 제어·로봇·시스템학회 2022 International Journal of Control, Automation, and Vol.20 No.3

        Bilateral teleoperation robots with force feedback enable humans to accomplish these tasks without exposing them to these hazardous environments. Its stability and transparency describe the performance of bilateral teleoperation systems with force feedback. Bilateral teleoperation with force feedback enables humans to combine tactics with optesthesia. However, the force feedback may lead to bilateral teleoperation instability if the communication channels’ time delay exists. The instability of bilateral teleoperation with force feedback, which is brought in by the time delay, has become one of the complicated problems researchers need to solve. Transparency is one of the leading design objectives of the teleoperation system. There are two evaluation criteria for transparency: the accuracy of the position followed by the master mechanical arm and the accuracy of the feedback received by the slave arm from the master arm. The main content of this paper is as follows: 1) This paper researches and summarizes the control structures and control algorithms of several well-developed force-feedback bilateral teleoperation systems and decides to improve the PBTDPA algorithm, which aligns with practical application requirements. 2) The fourchannel structure makes the transparency of force-feedback bilateral teleoperation systems perfect in theory. This paper uses the four-channel structure combined with the PBTDPA algorithm to improve the transparency of the approach. 3) Moreover, the delay predictor is used to improve the four-channel power-based time domain passivity approach (PBTDPA) control strategy. The delay differential predictor is added to the communication channel. The delay change rate differential predictor can estimate the communication channel’s delay change rate instead of the maximum delay change rate to improve transparency. The simulation experiment of the improved control strategy was carried out. The results show the excellent performance of our design.

      • SCOPUSKCI등재

        Synthesis and Chromatographic Characteristics of Multidentate Ligand-Boned Silica Stationary Phases

        Li, Rong,Wang, Yan,Chen, Guo-Liang,Shi, Mei,Wang, Xiao-Gang,Zheng, Jian-Bin Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.8

        To improve the separation property and stability of metal chelate Cu(II) column, three new kinds of multidentate aminocarboxy silica columns with cation-exchange properties were synthesized using glutamic acid (Glu), glutamic acidbromoacetic acid (Glu-BAA), glutamic acid-bromosuccinic acid (Glu-BSUA) as ligands and silica gel as matrix. The standard proteins were separated with prepared chromatographic columns. The stationary phases exhibited the metal chelate property after fixing copper ion (II) on the synthesized multidentate ligand silica columns. The binding capacity of immobilized metal ion was related with the dentate number of multidentate ligands. Chromatographic behavior of proteins and the leakage of immobilized metal ion on multidentate chelate Cu(II) columns were affected by the dentate number of multidentate ligands and competitive elution system directly. The results showed that quinquedentate Glu-BSUA-Cu(II) column exhibited better chromatographic property and stability as compared with tridentate Glu-Cu(II) column, tetradentate Glu-BAA-Cu(II) column and commonly used IDA-Cu(II) column.

      • SCOPUSKCI등재

        Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand

        Li, Rong,Ju, Ming-Yang,Chen, Bin,Sun, Qing-Yuan,Chen, Guo-Liang,Shi, Mei,Wang, Xiao-Gang,Zheng, Jian-Bin Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.2

        An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.

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