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      • Research of Sentiment Classification for Tibetan Texts by Supervised Learning

        Lirong Qiu,Zhen Zhang 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.9

        Increasing number of subjective text appears on the internet which contains a lot of information. In this paper, we study how to apply supervised learning techniques to solve sentiment classification problems. Using the Tibetan news as data, we find that standard supervised learning techniques definitively outperform human-produced baselines. Moreover, we find that selecting the words with words with polarity as feature, the special syntactic structure such as exclamation sentence pattern, etc. as feature can improve the performance of sentiment classification. Conclusively, the research of sentiment analysis is a more challenging problem.

      • Network Characteristics Analysis of Microblog Public Opinion

        Lirong Qiu,Jie Li,Zhen Hai Zhang,Yi Lei Wang 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.10

        This paper uses public opinion propagation structure of Sina microblog as research object, it sets up simulation model of public opinion propagation structures based on complex network theory. Through the analysis of the degree distribution, clustering coefficient and community structure of the model, the validity of the model has been well confirmed. The paper also conducts research and analysis towards propagation quantity of the hot topic within 800 well-known spread microblog from 2013 to 2015, the paper establishes a community structure, through the simulation and demonstration of the community structure, it declares the community structure characteristic under the complex network environment.

      • KCI등재

        Synthesis and Magnetic Properties of FeCo Alloy Nanowires via AC Frequency Conversion Electrodeposition

        Lirong Wang,Shunzhen Feng,Tingting Lu,Lizhen Zhen,Jiwei Zhang,Lihu Liu 한국자기학회 2022 Journal of Magnetics Vol.27 No.3

        Binary alloy nanowires of Fe3Co7 system are synthesized in the highly ordered porous anodic aluminum oxide (PAA) templates by AC frequency (5, 50, 120, and 200 Hz) conversion electrodeposition method. High resolution field emission transmission electron microscope (HRTEM) and Lorenz TEM (LTEM) were used to study the morphology and the magnetic domain structure of the Fe3Co7 alloy nanowires, respectively. Magnetic measurements showed that the M-H curves presented a discontinuity in a restricted magnetic field, but with high squareness (about 90 %). Quantitative local measurements of the magnetic properties of the nanowires are explored by differential phase contrast (DPC) imaging. The magnetic properties, however, were significantly affected by the AC frequency, which is correlated with the specific magnetic structure formation of Bloch line. We reported herein a detailed investigation on Fe3Co7 alloy nanowires and their magnetic properties.

      • A Sentiment Calculation Method Based on Tibetan Semantic Relations

        Zhen Zhang,Lirong Qiu 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.9

        Sentiment analysis is shown significant and indispensable status in hot topic, public-opinion poll, knowledge acquiring and recommended goods fields, which is the fundamental work for natural language processing. This paper proposes an approach to build the Tibetan sentiment dictionary and to calculate the sentiment value base on the Tibetan semantic relations. We test our approach on experimental corpus crawled from Sina weibo and the experimental results demonstrate good performance on Tibetan language.

      • KCI등재

        Co-pyrolysis characteristics of coal and natural gas

        Jianmin Zhang,Lirong Kang,Hui Lian,Ming Luo 한국화학공학회 2007 Korean Journal of Chemical Engineering Vol.24 No.3

        co-pyrolysis experiment of coal and natural gas was investigated on a fixed-bed reactor. SEM was usedto study the structure changes of the exterior surface of char prepared in this co-pyrolysis experiment, while GC wasalso utilized to analyze the associated gas. The result showed that, with increasing temperature, the coal char tendedto agglomerate. GC and SEM results show that the CH4 decomposition on the exterior surface of char was turned tofilamentous char and extended around like coral. It was also proved that the co-pyrolysis of coal and natural gas pro-moted syngas production. A synergistic effect of coal and natural gas does exist during this process.

      • KCI등재

        Entropic Image Thresholding Segmentation Based on Gabor Histogram

        ( Sanli Yi ),( Guifang Zhang ),( Jianfeng He ),( Lirong Tong ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.4

        Image thresholding techniques introducing spatial information are widely used image segmentation. Some methods are used to calculate the optimal threshold by building a specific histogram with different parameters, such as gray value of pixel, average gray value and gradient-magnitude, etc. However, these methods still have some limitations. In this paper, an entropic thresholding method based on Gabor histogram (a new 2D histogram constructed by using Gabor filter) is applied to image segmentation, which can distinguish foreground/background, edge and noise of image effectively. Comparing with some methods, including 2D-KSW, GLSC-KSW, 2D-D-KSW and GLGM-KSW, the proposed method, tested on 10 realistic images for segmentation, presents a higher effectiveness and robustness.

      • KCI등재

        Whole transcriptome mapping reveals the lncRNA regulatory network of TFP5 treatment in diabetic nephropathy

        Luo Hongyan,Yang Lirong,Zhang Guoqing,Bao Xi,Ma Danna,Li Bo,Cao Li,Cao Shilu,Liu Shunyao,Bao Li,E Jing,Zheng Yali 한국유전학회 2024 Genes & Genomics Vol.46 No.5

        Background TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production. However, the role of TFP5 in diabetic nephropathy (DN) is still unclear. Objective This study aims to characterize the transcriptome profiles of mRNA and lncRNA in TFP5-treated DN mice to mine key lncRNAs associated with TFP5 efficacy. Methods We evaluated the role of TFP5 in DN pathology and performed RNA sequencing in C57BL/6J control mice, C57BL/6J db/db model mice, and TFP5 treatment C57BL/6J db/db model mice. The differentially expressed lncRNAs (DElncRNAs) and mRNAs (DEmRNAs) were analyzed. WGCNA was used to screen hub-gene of TFP5 in treatment of DN. Results Our results showed that TFP5 therapy ameliorated renal tubular injury in DN mice. In addition, compared with the control group, the expression profile of lncRNAs in the model group was significantly disordered, while TFP5 alleviated the abnormal expression of lncRNAs. A total of 67 DElncRNAs shared among the three groups, 39 DElncRNAs showed a trend of increasing in the DN group and decreasing after TFP treatment, while the remaining 28 showed the opposite trend. DElncRNAs were enriched in glycosphingolipid biosynthesis signaling pathways, NF-κB signaling pathways, and complement activation signaling pathways. There were 1028 up-regulated and 1117 down-regulated DEmRNAs in the model group compared to control group, and 123 up-regulated and 153 down-regulated DEmRNAs in the TFP5 group compared to the model group. The DEmRNAs were involved in PPAR and MAPK signaling pathway. We confirmed that MSTRG.28304.1 is a key DElncRNA for TFP5 treatment of DN. TFP5 ameliorated DN maybe by inhibiting MSTRG.28304.1 through regulating the insulin resistance and PPAR signaling pathway. The qRT-PCR results confirmed the reliability of the sequencing data through verifying the expression of ENSMUST00000211209, MSTRG.31814.5, MSTRG.28304.1, and MSTRG.45642.14. Conclusion Overall, the present study provides novel insights into molecular mechanisms of TFP5 treatment in DN. Background TFP5 is a Cdk5 inhibitor peptide, which could restore insulin production. However, the role of TFP5 in diabetic nephropathy (DN) is still unclear. Objective This study aims to characterize the transcriptome profiles of mRNA and lncRNA in TFP5-treated DN mice to mine key lncRNAs associated with TFP5 efficacy. Methods We evaluated the role of TFP5 in DN pathology and performed RNA sequencing in C57BL/6J control mice, C57BL/6J db/db model mice, and TFP5 treatment C57BL/6J db/db model mice. The differentially expressed lncRNAs (DElncRNAs) and mRNAs (DEmRNAs) were analyzed. WGCNA was used to screen hub-gene of TFP5 in treatment of DN. Results Our results showed that TFP5 therapy ameliorated renal tubular injury in DN mice. In addition, compared with the control group, the expression profile of lncRNAs in the model group was significantly disordered, while TFP5 alleviated the abnormal expression of lncRNAs. A total of 67 DElncRNAs shared among the three groups, 39 DElncRNAs showed a trend of increasing in the DN group and decreasing after TFP treatment, while the remaining 28 showed the opposite trend. DElncRNAs were enriched in glycosphingolipid biosynthesis signaling pathways, NF-κB signaling pathways, and complement activation signaling pathways. There were 1028 up-regulated and 1117 down-regulated DEmRNAs in the model group compared to control group, and 123 up-regulated and 153 down-regulated DEmRNAs in the TFP5 group compared to the model group. The DEmRNAs were involved in PPAR and MAPK signaling pathway. We confirmed that MSTRG.28304.1 is a key DElncRNA for TFP5 treatment of DN. TFP5 ameliorated DN maybe by inhibiting MSTRG.28304.1 through regulating the insulin resistance and PPAR signaling pathway. The qRT-PCR results confirmed the reliability of the sequencing data through verifying the expression of ENSMUST00000211209, MSTRG.31814.5, MSTRG.28304.1, and MSTRG.45642.14. Conclusion Overall, the present study provides novel insights into molecular mechanisms of TFP5 treatment in DN.

      • KCI등재

        The role of botulinum toxin type A related axon transport in neuropathic pain induced by chronic constriction injury

        Huilian Bu,Pengfei Jiao,Xiaochong Fan,Yan Gao,Lirong Zhang,Haiming Guo 대한통증학회 2022 The Korean Journal of Pain Vol.35 No.4

        Background: The mechanism of peripheral axon transport in neuropathic pain is still unclear. Chemokine ligand 13 (CXCL13) and its receptor (C-X-C chemokine receptor type 5, CXCR5) as well as GABA transporter 1 (GAT-1) play an important role in the development of pain. The aim of this study was to explore the axonal transport of CXCL13/CXCR5 and GAT-1 with the aid of the analgesic effect of botulinum toxin type A (BTX-A) in rats. Methods: Chronic constriction injury (CCI) rat models were established. BTX-A was administered to rats through subcutaneous injection in the hind paw. The pain behaviors in CCI rats were measured by paw withdrawal threshold and paw withdrawal latencies. The levels of CXCL13/CXCR5 and GAT-1 were measured by western blots. Results: The subcutaneous injection of BTX-A relieved the mechanical allodynia and heat hyperalgesia induced by CCI surgery and reversed the overexpression of CXCL13/CXCR5 and GAT-1 in the spinal cord, dorsal root ganglia (DRG), sciatic nerve, and plantar skin in CCI rats. After 10 mmol/L colchicine blocked the axon transport of sciatic nerve, the inhibitory effect of BTX-A disappeared, and the levels of CXCL13/CXCR5 and GAT-1 in the spinal cord and DRG were reduced in CCI rats. Conclusions: BTX-A regulated the levels of CXCL13/CXCR5 and GAT-1 in the spine and DRG through axonal transport. Chemokines (such as CXCL13) may be transported from the injury site to the spine or DRG through axonal transport. Axon molecular transport may be a target to enhance pain management in neuropathic pain.

      • SCOPUSKCI등재

        Removal and fate of carbamazepine in the microbial fuel cell coupled constructed wetland system

        Jingyi Xie,Haixiao Li,Shiyu Wang,Hao Chen,Wei Jiang,Lin Zhang,Lianjie Wang,Yufeng Wu,Lirong Li,Xueqiang Lu 대한환경공학회 2022 Environmental Engineering Research Vol.27 No.3

        Carbamazepine (CBZ), which is difficult to remove in the wastewater treatment system and easily forms toxic transformation products during the treatment process, is one of the priority pollutants of pharmaceuticals and personal care products (PPCPs). Increasing attention has been paid to explore their treatment technology without side effects from the treatment products. This study aims to reveal the removal and transformation of CBZ in the microbial fuel cell coupled constructed wetland (CW-MFC) system. The CW-MFC system was operated continuously at room temperature for nearly 80 days. The results show that CW-MFC system can effectively remove CBZ with an average removal rate of 97%. Three transformation products were identified by liquid chromatography−high-resolution mass spectrometry: 2-(2-oxoquinazolin-1(2H)-yl) benzoic acid (TP267), methyl 2-(2-oxoquinazolin-1(2H)-yl) benzoate (TP281), 2-(2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl) benzoic acid (TP283). Except TP281 in the influent, the other transformation products were formed in the system, which indicated that TP267 and TP283 were the main transformation products of CBZ. The formation pathway of transformation products could be explained by reactions including oxidation, hydrolysis, bond rupture and intramolecular reaction. The results also indicate that the CW-MFC system might be a promising technology for PPCPs treatment.

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