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- 저자 : Liqiang Chen (검색결과 9 건)
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Liqiang Zhong,Minghua Wang,Daming Li,Shengkai Tang,Tongqing Zhang,Wenji Bian,Xiaohui Chen 한국유전학회 2018 Genes & Genomics Vol.40 No.11
Freshwater gobies Rhinogobius cliffordpopei and R. giurinus are invasive species with particular concern because they have become dominant and were fierce competitors in the invaded areas in Yunnan-Guizhou Plateau (southwest of China). Information about genetic characteristics of R. giurinus have been published, but there were still no relevant reports about R. cliffordpopei. In present study, the complete mitochondrial genome of R. cliffordpopei was determined, which was 16,511 bp in length with A + T content of 51.1%, consisting of 13 protein-coding genes, 22 tRNAs, 2 ribosomal RNAs, and a control region. The gene composition and the structural arrangement of the R. cliffordpopei complete mtDNA were identical to most of other teleosts. Phylogenetic analyses placed R. cliffordpopei in a well-supported monophyletic cluster with other Rhinogobius fish. But the phylogenetic relationship between genus Rhinogobius and Tridentiger remained to be resolved.
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Implementation of a Stand-alone Photovoltaic Pumping System with Maximum Power Point Tracking
Zhao Zhengming,Chen Kunlun,Yuan Liqiang 전력전자학회 2001 ICPE(ISPE)논문집 Vol.2001 No.10
Photovoltaic (PV) pumping systems with maximum power point tracking (MPPT) technique aims at obtaining the highest possible power to the pump under various insolation and temperature, thus overcomes the mismatch between the photovoltaic panel and the pumping load. A simple method of tracking the maximum power points and forcing the system to operate close to these points is presented in this paper. The MC68HC908GP32 micro control unit (MCU) is employed to implement the proposed MPPT controller. Experimental results will also show the performances of the photovoltaic pumping system with the MPPT technique.<br/>
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Xiaoxing Yang,Jiachun Zhou,Liqiang Fan,Zhen Qin,Qiming Chen,Liming Zhao 한국식품과학회 2018 Food Science and Biotechnology Vol.27 No.6
Fermented vegetable–fruit beverages are a popular fermented food, with many potential health benefits. In this study, two commercial Lactobacillus plantarum strains were selected to ferment a beverage containing apples, pears, and carrots. The metabolites and antioxidant activities were examined during the fermentation process. Results showed that lactic acid and acetic acid accumulated gradually, whereas malic acid decreased. Glucose and fructose increased from 0.48 and 14.8 g/L to 7.7 and 20.8 g/L, respectively, while sucrose decreased slightly. Ascorbic acid also increased continuously during the fermentation to 90.74 mg/100 mL. DPPH and ABTS radical scavenging activity and FRAP reached their maximum value after 4–8 days. The accumulation of TPC, TFC, and SOD reached their maximum value on the 8th day of fermentation. Our study revealed that the L. plantarum-fermented vegetable–fruit beverage showed significant antioxidant activity, which is helpful in evaluating the fermentation end-point and developing a high-quality fermented beverage.
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Rong Zeng,Renzhong Qiao,Zehu Wang,Hongran Wang,Liqiang Chen,Lin Yang,Liming Hu,Zelin Li 한국고분자학회 2012 Macromolecular Research Vol.20 No.4
Two kinds of chitosan-stavudine (d4T) conjugates, chitosan-O-isopropyl-5'-O-d4T monophosphate conjugate (Cs-P-d4T) with a phosphoramide linkage and chitosan-5'-O-succinyl-d4T conjugate (Cs-S-d4T) with a succinic spacer, were synthesized using an Atherton-Todd reaction and carbodiimide coupling reaction, respectively, and then structurally characterized. Their in vitro drug release behaviors and anti-human immunodeficiency virus (HIV) activity were investigated and compared. Both of the chitosan-d4T conjugates more strongly prefer to release corresponding d4T derivatives rather than free d4T in a prolonged manner but have different hydrolysis routes. The anti-HIV activity and cytotoxicity evaluated in the MT4 cell line revealed that the anti-HIV selectivity index was in the following order: Cs-P-d4T > d4T >> Cs-S-d4T since the released d4T-5'-(O-isopropyl) monophosphate from Cs-P-d4T can bypass the rate-limiting bottleneck of nucleoside phosphorylation, while the released 5'-O-succinyl-d4T from Cs-Sd4T has to be hydrolyzed to d4T and then successively phosphorylated to its active form to exert antiviral activity. The results suggested that constructing a chitosan-nucleoside reverse transcriptase inhibitor (NRTI) conjugate with a phosphoramide linkage may be an efficient approach for improving NRTI therapy efficacy in antiretroviral treatment.
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오도연,Toshihiko Doi,Kuniaki Shirao,이근욱,박숙련,Ying Chen,Liqiang Yang,Olga Valota,방영주 대한암학회 2015 Cancer Research and Treatment Vol.47 No.4
Purpose This phase I trial evaluated the question of whether the standard starting dose of axitinibcould be administered in combination with therapeutic doses of cisplatin/capecitabine inpatients with previously untreated advanced gastric cancer, and assessed overall safety,pharmacokinetics, and preliminary antitumor activity of this combination. Materials and MethodsPatients in dose level (DL) 1 received axitinib 5 mg twice a day (days 1 to 21) with cisplatin80 mg/m2 (day 1) and capecitabine 1,000 mg/m2 twice a day (days 1 to 14) in 21-daycycles. Maximum tolerated dose (MTD) was the highest dose at which ! 30% of the first 12patients experienced a dose-limiting toxicity (DLT) during cycle 1. Ten additional patientswere enrolled and treated at the MTD in order to obtain additional safety and pharmacokineticdata. ResultsThree DLTs occurred during cycle 1 in three (25%) of the first 12 patients: ruptured abdominalaortic aneurysm, acute renal failure, and > 5 consecutive days of missed axitinib dueto thrombocytopenia. DL1 was established as the MTD, since higher DL cohorts were notplanned. Common grade 3/4 non-hematologic adverse events in 22 patients treated atDL1 included hypertension (36.4%) and decreased appetite and stomatitis (18.2% each). Cisplatin/capecitabine slightly increased axitinib exposure; axitinib decreased capecitabineand 5-fluorouracil exposure. Eight patients (36.4%) each had partial response or stable disease. Median response duration was 9.1 months; median progression-free survival was3.8 months. ConclusionIn patients with advanced gastric cancer, standard doses of axitinib plus therapeutic dosesof cisplatin and capecitabine could be administered in combination. Adverse events weremanageable.
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Hu, Zhe,Liu, Qiannan,Zhang, Kai,Zhou, Limin,Li, Lin,Chen, Mingzhe,Tao, Zhanliang,Kang, Yong-Mook,Mai, Liqiang,Chou, Shu-Lei,Chen, Jun,Dou, Shi-Xue American Chemical Society 2018 ACS APPLIED MATERIALS & INTERFACES Vol.10 No.42
<P>Dual ion batteries based on Na<SUP>+</SUP> and PF<SUB>6</SUB><SUP>-</SUP> received considerable attention due to their high operating voltage and the abundant Na resources. Here, cheap and easily obtained graphite that served as a cathode material for dual ion battery delivered a very high average discharge platform (4.52 V vs Na<SUP>+</SUP>/Na) by using sodium hexafluorophosphate in propylene carbonate as electrolyte. Moreover, the all-carbon dual ion batteries with graphite as cathode and hard carbon as anode exhibited an ultrahigh discharge voltage of 4.3 V, and a reversible capacity of 62 mAh·g<SUP>-1</SUP> at 40 mA·g<SUP>-1</SUP>. Phase changes have been investigated in detail through in situ X-ray diffraction and in situ Raman characterizations. The stable structure provides long life cycling performance, and the pseudocapacitance behavior also demonstrates its benefits to the rate capability. Thus, dual ion batteries based on sodium chemistry are very promising to find their applications in future.</P> [FIG OMISSION]</BR>
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Zhou, Limin,Zhang, Kai,Sheng, Jinzhi,An, Qinyou,Tao, Zhanliang,Kang, Yong-Mook,Chen, Jun,Mai, Liqiang Elsevier 2017 Nano energy Vol.35 No.-
<P><B>Abstract</B></P> <P>Considering inherent large structural deterioration of conversion-type anode materials during repeated sodiation/desodiation process, the ingenious integration of both nanostructure engineering and chemical hybridization is highly desirable and challenging. Here, ultrafine CoS nanoparticles embedded in porous carbon nanorods (denoted as 7-CoS/C) were facilely fabricated via simultaneous in-situ carbonization and sulfidation of Co-metal organic frameworks (Co-MOF) and have been applied as anode materials for sodium-ion batteries (SIBs). Benefiting from the advantageous embedding architecture between the nanoparticles and porous nanorods, the 7-CoS/C delivers long-term cycling stability (542mAhg<SUP>−1</SUP> after 2000 cycles with a capacity retention of 91.4% at 1Ag<SUP>−1</SUP>) and excellent rate performance (discharge capacities of 510mAhg<SUP>−1</SUP> at 5Ag<SUP>−1</SUP> and 356mAhg<SUP>−1</SUP> even at 40Ag<SUP>−1</SUP>), which is proved to be characterized of partial pseudocapacitive behaviors during the sodiation/desodiation process. In addition, Na<SUB>3</SUB>V<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB>/7-CoS/C full cell with excessive amount of Na<SUB>3</SUB>V<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB> has been assembled and exhibits a capacity of 352mAhg<SUP>−1</SUP> at 0.5Ag<SUP>−1</SUP>. This meaningful approach can be extended to build embedded porous structure of other hybrid composites for next-generation energy-storage technology.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The embedded hybrid architecture of the 7-CoS/C is favorable for relieving volume expansion and immobilizing the CoS nanoparticles sites. </LI> <LI> The effect of different electrolyte on the 7-CoS/C/Na system was investigated. </LI> <LI> The variation of structure and valence in Na<SUP>+</SUP> insertion/extraction process of the 7-CoS/C is presented by <I>ex situ</I> XANES. </LI> <LI> The unique structural feature of the 7-CoS/C reveals obvious advantages at more than 1Ag<SUP>−1</SUP> compared with other anode materials. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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