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Eun-Do Kim,Jin-Kwon Lee,Jin-Kyu Cho,Jae-Myung Kim,Ji-Ho Park,Ju-Yeon Kim,Sang-Ho Jeong,Young-Tae Ju,Chi-Young Jeong,Eun-Jung Jung,Young-Joon Lee1,Soon-Chan Hong,곽승진 대한종양외과학회 2019 Korean Journal of Clinical Oncology Vol.15 No.2
Purpose: Whether subtotal or total colectomy with primary anastomosis (PA) is safer than Hartmann procedure (HP) for left-sided colon cancer obstruction or perforation remains controversial. The purpose of this study was to compare postoperative morbidity, mortality, and defecation frequency between PA and HP for left-sided colon cancer obstruction or perforation. Methods: This retrospective study enrolled 54 patients from January 2014 to February 2018 who underwent emergency surgery due to left-sided colon cancer obstruction or perforation. Results: PA was carried out in 20 patients while HP was performed for 34 patients. Thirty-day mortality did not show significant difference between the two groups (15.0% vs. 14.7%, P=1.000). No anastomotic leakage occurred in PA group while three (8.8%) cases of stump leakage occurred in HP group. Stoma repair was performed for 13 cases (44.8%) and stoma reformation was performed for one case in HP group (7.7%). Stoma related complications occurred in five cases (17.24%). For patients after stoma repair, defecation frequency at 3 months after operation was 2.91±2.88 times per day in PA group and 2.86±2.63 times per day in HP group. At 1 year after operation, defecation frequency was changed to 1.40±1.12 times per day in PA group and 1.17±0.39 times per day in HP group. Conclusion: Primary ileosigmoid or ileorectal anastomosis for left-sided colon cancer obstruction or perforation is safe, and shows similar outcome of defecation frequency compared to H
Lee, Hyun-Ho,Kim, Sang-Joon,Shin, Hyun-Jae,Park, Ji-Yeon,Yang, Ji-Won The Korean Society for Biotechnology and Bioengine 2002 Biotechnology and Bioprocess Engineering Vol.7 No.6
Methyl mercaptan oxidase was successfully induced in Thiobacillus thioparus TK-m using methyl mercaptan gas, and was purified for the detection of mercaptans. The purification procedure Involved a DEAE (diethylaminoethyl) -Sephacel, or Superose 12, column chromatography with recovery yields of 47.5 and 48.5%, and specific activities of 374 and 1240.8 units/mg-protein, respectively, The molecular weight of the purified methyl mercaptan oxidase was 66.1kDa, as determined by SDS-PAGE. The extract, from gel filtration chromatography oxidizes methyl mercaptan, producing formaldehyde, which can be easily detected by the purpald-coloring method. The optimized temperature for activity was found to be at 55$\^{C}$. This enzyme was inhibited by both NH$_4$Cl and (NH$_4$)$_2$SO$_4$, but was unaffected by either KCl or NaCl at less than 200 mM. With K$_2$SO$_4$, the activity decreased at 20 mM, but recovered at 150 mM. In the presence of methanol, full activity was maintained, but decreased in the presence of glycerin, ethanol and acetone 43, 78 and 75%, respectively.
Low-Molecular-Weight White Organic-Light-Emitting-Devices using Direct Color Mixing Method
Lee, Sung-Soo,Song, Tae-Joon,Ko, Myung-Soo,Cho, Sung-Min The Korean Infomation Display Society 2002 Journal of information display Vol.3 No.2
In order to achieve white emission from organic light emitting devices (OLEDs), five distinct structures were fabricated and tested. The white emission was obtained using two different color-emitting materials (yellow from rubrene-doped $Alq_3$ and blue from DPVBi) with or without a carrier-blocking layer. For enhancing the red emission, two types of devices with three-color emitting materials were fabricated. The white emission, close to the CIE coordinate of (0.3,0.3), was achieved by using two blocking layers as well that as without a blocking layer. This paper covers the subject of controlling the location of exciton recombination zone. It has been found that there is a trade-off in that the devices with three color emitting layers do not show as much luminescence efficiency compared to those with two color emitting layers, but rather, show distinct red emission in the resultant emission spectra. The highest power efficiency was measured to be 1.15lm/W at 2,000 $cd/m^2$ for a structure with two color-emitting layers.
Lee, Dong-Kyu,Kim, Sung-Joon 한국곤충학회 2001 Entomological Research Vol.31 No.3
The result of surveillance of adult mosquitos in Ihgok-ri, Cheolma-myun, Gijang-gun, Busan located in the south-east of the Korean peninsula from 1996 to 1999 are presented. A light trap was operated twice a week from May to October each year. Average numbers of female mosquitoes per trap-night were 366.5, 751.6, 406.0 and 468.7 adults in 1996, 1997, 1998 and 1999, respectively. Total 9 species comprising 4 genera were collected. They are Aedes albopictus, Ae. vexans, Ae. togoi, Anopheles sinensis, An. sineroides, Armigeres subalbatus, Culex orientalis, Cx. tritaeniorhynchus and Cx. pipiens. An. sinensis (60.2 %) was the most abundant, followed by Cx. tritaeniorhynchus (27.1 %) and Cx. pipiens pallens (8.6%). A population density of An. sinensis in 1999 was 3.2 times lower than that in 1997. However, The density of the species in 1999 was not much different from those in 1996 and 1998. It was assumed that major factors to influence population of An. sinensis were temperature(r = 0.90) and precipitation(r = 0.74) during three summer months.
( Joon Sung Kim ),( Byung-wook Kim ),( Sung Min Park ),( Ki-nam Shim ),( Seong Woo Jeon ),( Sang-wook Kim ),( Yong Chan Lee ),( Hee Seok Moon ),( Si Hyung Lee ),( Woon Tae Jung ),( Jin Il Kim ),( Kyou 대한소화기학회 2018 Gut and Liver Vol.12 No.3
Background/Aims: Rebleeding is associated with mortality in patients with peptic ulcer bleeding (PUB), and risk stratification is important for the management of these patients. The purpose of our study was to examine the risk factors associated with rebleeding in patients with PUB. Methods: The Korean Peptic Ulcer Bleeding registry is a large prospectively collected database of patients with PUB who were hospitalized between 2014 and 2015 at 28 medical centers in Korea. We examined the basic characteristics and clinical outcomes of patients in this registry. Univariate and multivariate analyses were performed to identify the factors associated with rebleeding. Results: In total, 904 patients with PUB were registered, and 897 patients were analyzed. Rebleeding occurred in 7.1% of the patients (64), and the 30-day mortality was 1.0% (nine patients). According to the multivariate analysis, the risk factors for rebleeding were the presence of co-morbidities, use of multiple drugs, albumin levels, and hematemesis/hematochezia as initial presentations. Conclusions: The presence of co-morbidities, use of multiple drugs, albumin levels, and initial presentations with hematemesis/hematochezia can be indicators of rebleeding in patients with PUB. The wide use of proton pump inhibitors and prompt endoscopic interventions may explain the low incidence of rebleeding and low mortality rates in Korea. (Gut Liver 2018;12:271-277)
( Sang Hoon Park ),( Choong Kee Park ),( Jin Woo Lee ),( Young Seok Kim ),( Sook-Hyang Jeong ),( Yun Soo Kim ),( Ju Hyun Kim ),( Seong Gyu Hwang ),( Kyu Sung Rim ),( Hyung Joon Yim ),( Jae Youn Cheong 대한소화기학회 2011 Gut and Liver Vol.6 No.1
Background/Aims: We aimed to evaluate the effi cacy and safety of peginterferon plus ribavirin for chronic hepatitis C (CHC) patients under real life setting in Korea. Methods: We retrospectively analyzed the medical records of 758 CHC patients treated with peginterferon plus ribavirin between 2000 and 2008 from 14 university hospitals in the Gyeonggi- Incheon area in Korea. Results: Hepatitis C virus (HCV) genotype 1 was detected in 61.2% of patients, while genotype 2 was detected in 35.5%. Baseline HCV RNA level was ≥6×105 IU/mL in 51.6% of patients. The sustained virological response (SVR) rate was 59.6% regardless of genotype; 53.6% in genotype 1 and 71.4% in genotype 2/3. On multivariate analysis, male gender (p=0.011), early virological response (p<0.001), genotype 2/3 (p<0.001), HCV RNA <6×105 IU/ mL (p=0.005) and adherence to the drug >80% of the planned dose (p<0.001) were associated with SVR. The rate of premature discontinuation was 35.7%. The main reason for withdrawal was intolerance to the drug due to common adverse events or cytopenia (48.2%). Conclusions: Our data suggest that the effi cacy of peginterferon and ribavirin therapy in Koreans is better in Koreans than in Caucasians for the treatment of CHC, corroborating previous studies that have shown the superior therapeutic effi cacy of this regimen in Asians. (Gut Liver 2012;6:98-106)