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A Selective Compressed Cache Architecture For High Capacity And Bandwidth
Lee,JangSoo,Kim,ShinDug THE RESEARCH INSTITUTE OF ASIC DESIGN YONSEI UNIVE 1998 Journal of the Research Institute of ASIC Design Vol.5 No.1
Decompression overhead may set off the benefits of on-line data compression technique, which can increase both the capacity and bandwidth of storage systems. In this paper, a selective compressed memory system (SCMS) based on selective compression technique and decompression overhead hiding presented for efficient access of selectively compressed data. The results from trace-driven simulation show that the selective compression technique can provide around 47% decrease in the data transfer time and 10% decrease in the on-chip cache misses over the conventional memory systems.
이장수(Jangsoo Lee),김고려(Koryu Kim),동인숙(Insook Dong) 한국정보과학회 1993 한국정보과학회 학술발표논문집 Vol.20 No.1
본 연구에서는 A* Algorithm의 일종인 WSA를 사용하여 실내이동로보트를 위한 경로계획을 수행하는 소프트웨어를 개발하였다. 전체 시스템의 구성은 각각 Task Planner, Path Planner, Navigator, MMIS로 이루어졌으며, SUN의 UNIX에서 제공되는 Inter Process Communication을 사용하여 모듈간의 Interface를 구현하였다. 사용된 지도정보는 대상을 다각형으로 처리한 꼭지점 값을 사용하여 Vision System에 대비하였다.
박장수(Jangsoo Park),이재원(Jayone Lee),이성범(Seong Beom Lee),김흥섭(Heungseob Kim) 한국자동차공학회 2010 한국자동차공학회 부문종합 학술대회 Vol.2010 No.5
The purpose of this paper is to compare with estimation of equivalent fatigue load in time domain and frequency domain. The fatigue analysis for random loads is discussed in several papers. In general, Equivalent fatigue load in time-domain is estimated by rainflow cycle counting. In case of frequency domain, it can estimate through probability density function of Dirlik`s method that directly use power spectrum density of stress. Probability density function of Dirlik`s method is function of spectral moment only. For verification of performance with two methods, simulations is performed with general random signal and FEM analysis.
Oh, Jaeseong,Lee, SeungHwan,Kim, Anhye,Yoon, Jangsoo,Jang, Kyungho,Lee, Doo H.,Cho, Sunyoung,Lee, Sang Rim,Yu, Kyung-Sang,Chung, Jae-Yong Hall Associates, etc 2018 The Journal of Clinical Pharmacology Vol.58 No.1
<P>VVZ-149, a dual antagonist of GlyT2 and 5HT(2)A receptors, is an investigational analgesic with a novel mechanism of action that is currently under early-stage clinical development as an injectable agent for the treatment of postoperative pain. Here, the safety, tolerability, and pharmacokinetics of VVZ-149 injections in healthy male volunteers were explored in a randomized, double-blind, single- and multiple-ascending-dose (SAD and MAD, respectively), placebo-controlled clinical study. Subjects randomly received a 4-hour intravenous infusion of 0.25-8 mg/kg VVZ-149 or placebo in the SAD study (n = 46) or a 4-hour intravenous infusion of 4-7 mg/kg VVZ-149 or placebo twice daily for 3 days in the MAD study (n = 20). Serial blood and urine samples were collected for the pharmacokinetic analysis of VVZ-149 and its active metabolite (VVZ-368). Noncompartmental and compartmental pharmacokinetic analyses were performed. Various dosing scenarios were simulated to identify the adequate dosing regimen for the subsequent trials. Plasma exposure to VVZ-149 and VVZ-368 showed a dose-proportional increase. VVZ-149 did not accumulate in the plasma, whereas the plasma concentration of VVZ-368 increased by 1.23- to 2.49-fold after the fifth and sixth doses, respectively, in the MAD trial. Among the simulated dosing regimens, a loading dose followed by a maintenance dose was found to be an optimal dosing regimen, yielding the effective concentration estimated from animal studies in rat models of neuropathic or inflammatory pain. Single- or multiple-dose administration of VVZ-149 was generally well tolerated. These results showed that 0.5-8 mg/kg VVZ-149 exhibited linear pharmacokinetic characteristics and can be safely administered in further clinical studies.</P>