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- 검색키워드
- 저자 : Lan-Ting Ma (검색결과 4 건)
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Lan-Ting Ma,Ying Wang,Weixing Zhang,HongfangWang,Zhenguo Liu,Baohua Xu 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.3
L-Leucine is an important factor for growth and development in animals. However, very little is known about the nutritional role and physiological function of L-leucine in honeybees. In this study,we determined the effects of Lleucine supplementation on protein synthesis and amino acid balance in honeybee larvae. First instar larvaewere fed different L-leucine diets (6.45, 8.45 and 10.45 mg/g) during the entire larval stage. After the larvae egested urate crystals, we analyzed the protein and amino acid metabolism indexes in the larvae. There was little effect of L-leucine on larval body weight and body protein content, but the hemolymph protein concentrations were higher in 8.45 and 10.45 mg/g groups than 6.45 mg/g group. Compared to the 6.45 mg/g group, L-leucine significantly increased the contents of Ala, Leu, Lys and Met in 8.45 mg/g group and continued to be increased in 10.45 mg/g group. L-Leucine affected many TOR signaling pathway- and L-leucine metabolism-related genes, including tor, 4Ebp1, bcaat et al. Moreover, aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatine kinase (CK) and lactate dehydrogenase (LDH) activities as well as the triglycerides (TG), total cholesterol (TCHO), uric acid (UA) and urea nitrogen (URER) contents in haemolymph were significantly different among treatments. These results suggested that many factors involved in the metabolism of L-leucine and larval hemolymph play important roles in honeybee protein synthesis and amino acid balance.
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Diversity in life history of queen and worker honey bees, Apis mellifera L.
Ying Wang,Lan-Ting Ma,Baohua Xu 한국응용곤충학회 2015 Journal of Asia-Pacific Entomology Vol.18 No.2
Queen and worker European honey bees (Apis mellifera L.) have similar growth trends but differ greatly in their morphology, physiology, function and developmental timeline. Here, the life history of queen and worker bees was characterized, and reference pictures are provided. The developmental rate of workers was found to differ as much as 3 days, even if the two types of bees were laid within 12 h of each other. We also present some interesting phenomena with regards to the developmental stages of queen and worker bees.
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Yu, Min,Liu, Lei,Zhang, Bing-Lan,Chen, Qi,Ma, Xue-Lei,Wu, Yu-Ke,Liang, Chun-Shui,Niu, Zhi-Min,Qin, Xin,Niu, Ting Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Background: This study was performed to analyze the prognostic implications of pretreatment or preoperative thrombocytosis in women with gynecologic malignancies. Material and Methods: We surveyed 2 medical databases, PubMed and EMBASE, to identified all relevant studies. A total of 14 (n=3,490) that evaluated the link between thrombocytosis and 5-year survival were included. REVMAN version 5.1 was used for our analysis and publication bias was evaluated using the Begg's funnel plot and tested by STATA 11.0. Risk ratios (RRs) with 95% confidence intervals (CIs) generated by the random effect model were used to assess the strength of any association. Results: 709(20.3%) of the 3,490 patients exhibited thrombocytosis (platelet counts > $400{\times}10^9/L$) at primary diagnosis, and their mortality was 1.62-fold higher compared with the others (RR=1.62, 95%CI=[1.28-2.05], p<0.0001). Thrombocytosis failed to have a stronger effect on the survival of advanced patients of stages III to IV in our study (n=478, RR=1.29, 95% CI=[1.13-1.48], p=0.0003), nor in women with cervical cancer in stage IB (n=1371, RR=1.73, 95% CI=[1.71-2.58], p=0.007). In addition, when adjusted for different carcinoma, it was associated with worse prognosis for all except the ones with vulvar cancer (n=201, RR=0.43, 95% CI=[0.14-1.29], p=0.13). Conclusions: This meta-analysis indicated that thrombocytosis might be associated with a worse prognosis for patients with gynecologic malignancies but without specificity or sensitivity for the ones in advanced stage. When adjusted for different gynecologic malignancies, it showed a significant effect on survival of all except vulvar cancers.
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Xue-Song Sun,Di-Han Liu,Sai-Lan Liu,Qiu-Yan Chen,Shan-Shan Guo,Yue-Feng Wen,Li-Ting Liu,Hao-Jun Xie,Qing-Nan Tang,Yu-Jing Liang,Xiao-Yun Li,Jin-Jie Yan,Ming-Huang Hong,Jun Ma,Lin-Quan Tang,Hai-Qiang M 대한암학회 2019 Cancer Research and Treatment Vol.51 No.4
Purpose The purpose of this study was to investigate the survival trends and patterns of failure in patients with stage II nasopharyngeal carcinoma (NPC) treated with radiotherapy (RT) and chemotherapy over the last 20 years. Materials and Methods Thirty-eight hundred and eight patients diagnosed with stage II NPC between January 1990 and December 2012 were involved in this retrospective cohort study. All patients were treated with RT. According to the main imaging techniques and RT technology, we categorized these patients into four calendar periods: 1990-1996, 1997-2002, 2003-2007, and 2008-2012. Overall survival (OS), progression-free survival (PFS), locoregional relapse-free survival (LRFS), and distant metastasis–free survival (DMFS) were served as the clinical outcome. Results After a median follow-up period of 84.7 months, we observed increasing trends in survival and disease control. The 3- and 5-year OS rates increased from 87.1% and 78.7% in the first calendar period to 97.4% and 94.5% in the last calendar period, respectively (p < 0.001). Additionally, significant increasing trends could be seen in the PFS and LRFS during the four calendar periods. In the subgroup analysis, the LRFS in patients older than 50 years at diagnosis showed greater improvement than younger patients. However, the rate of distant metastasis was stable and relatively low, as the 5-year DMFS ranged from 90.5% to 94.7% among the four calendar periods. Conclusion The survival rates in patients with stage II NPC showed increasing trends from 1990 to 2012. The advance of RT provided excellent locoregional control and enhanced OS.
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