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Asymptomatic carriage of Clostridioides difficile in pet shop puppies
Yuya Kimura(Yuya Kimura ),Satoshi Kameshima(Satoshi Kameshima ),Naoyuki Itoh(Naoyuki Itoh ) 한국예방수의학회 2023 예방수의학회지 Vol.47 No.2
Crowded pet shops can become infected with various pathogens. Although dog carriers of Clostridioides difficile tend to be asymptomatic, the toxigenic strains sometimes cause gastrointestinal symptoms in humans. The present study was conducted to determine the infection rate of C. difficile in pet shops. The feces of 137 dogs younger than one year of age, collected from four pet shops, were assessed by culture and PCR. Carriage rates of C. difficile in dogs aged ≤90, 91-180, and ≥181 day-old were 12.2% (10/82, 95% confidence interval: 6.0-21.3%), 0.0% (0/42, 95% confidence interval: 0.0-8.4%), and 7.7% (1/13, 95% confidence interval: 0.2-36.0%), respectively. Five C. difficile isolates carried genes encoding toxins A and B, while the remaining isolates contained only toxin B. However, none of the C. difficile carriers had diarrhea. These results highlight the necessity of promoting adequate hygiene precautions in pet shops to prevent infection by C. difficile.
Kimura, Fumiko,Horii, Shigeru,Arimoto, Itsuki,Doi, Toshiya,Yoshimura, Masato,Wada, Masahisa,Kimura, Tsunehisa American Chemical Society 2018 The Journal of physical chemistry A Vol.122 No.46
<P>Microcrystals of ErBa<SUB>2</SUB>Cu<SUB>4</SUB>O<SUB>8</SUB> suspended in a liquid medium were triaxially aligned by a frequency-modulated magnetic field and allowed a free rotational relaxation after the magnetic field was turned off. In situ X-ray diffraction measurements of the suspension were performed during relaxation, and the temporal change of the orientation fluctuation was monitored via broadening of the diffraction spots. The rotational diffusion constants were determined using the plot of the orientation fluctuation versus the elapsed time of rotational relaxation. The diffusion constants thus determined were in close agreement with those evaluated by the Stokes law but showed slight anisotropy, indicating that the microcrystals studied had shape anisotropy. The present method can provide a useful means for experimentally determining rotational diffusion constants of microcrystals suspended in viscous media. This paper shows that, due to the combination of the initial triaxial alignment and the subsequent monitoring of the relaxation process by means of X-ray diffraction, the diffusion constants along arbitrary crystallographic axes are determined separately.</P> [FIG OMISSION]</BR>
Preparation of Ru-C Nano-composite Film by MOCVD and Electrode Properties for Oxygen Gas Sensor
Kimura Teiichi,Goto Takashi 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
Ru-C nano-composite films were prepared by MOCVD, and their microstructures and their electrode properties for oxygen gas sensors were investigated. Deposited films contained Ru particles of 5-20 nm in diameter dispersed in amorphous C matrix. The AC conductivities associating to the interface charge transfer between Ru-C composite electrode and YSZ electrolyte were 100-1000 times higher than that of conventional paste-Pt electrodes. The emf values of the oxygen gas concentration cell constructed from the nano-composite electrodes and YSZ electrolyte showed the Nernstian theoretical values at low temperatures around 500 K. The response time of the concentration cell was 900 s at 500 K.
Design and Synthesis of Resin-Conjugated Tamiflu Analogs for Affinity Chromatography
Kimura, Yasuaki,Yamatsugu, Kenzo,Kanai, Motomu,Echigo, Noriko,Kuzuhara, Takashi,Shibasaki, Masakatsu Korean Chemical Society 2010 Bulletin of the Korean Chemical Society Vol.31 No.3
Two types of resin-conjugated Tamiflu analogs were synthesized by modifying our original synthetic route of oseltamivir phosphate (Tamiflu). The prepared resins bound to influenza virus neuraminidase, the main target of Tamiflu. The resins will be useful for isolating and identifying presumed endogenous vertebrate proteins that interact with Tamiflu, which might relate to the rarely observed abnormal behavior exhibited by some influenza patients treated with Tamiflu.
Recent Development of Various Inorganic Membranes in Japan
Kimura, Shoji The Membrane Society of Korea 1997 멤브레인 Vol.7 No.1
Two membrane-rdated research projects are now being developed in Japan and their main target is to develop new inorganic membranes. The first project is the R & D of membranes for carbon dioxide recovery at high temperature, conducted by the Japan Fine Ceramics Center (JFCC) and Japan Fine Ceramics Association (JFCA) under the supervision by the New Energy and Industrial Technology Development Organization (NEDO). The second one is the R & D of membranes for petroleum refinery and chemical processes, conducted by the Japan High Polymer Center (JHPC) under the supervision by the Petroleum Energy Center (PEC). Cooperating with these projects researchers in many universities and research institutes have been publishing many interesting data of inorganic membranes manufactured by various methods. Many such results are summarized and reported.