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      • KCI등재

        초등과학영재들의 창의성 유형 분석 : Creativity Styles of Elementary Science Gifted Students

        박신규,정원우,박영관,홍순천,박경미,김중욱 韓國英才學會 2011 영재교육연구 Vol.21 No.4

        본 연구의 목적은 TTCT 도형 검사를 통해 초등과학영재들의 창의성 유형(style)을 알아보는 것이다. 이를 위해 영재학생 206명을 대상으로 TTCT도형 검사를 실시하였으며 Kim (2006)의 이론에 의해 창의성의 2가지 유형이 나타나는지 알아보기 위해 요인분석을 실시하였다. 이를 바탕으로 지역별, 학년별, 성별에 따른 창의성 유형 비율과 창의성 유형별 성에 따른 창의성 수준 차이가 있는지를 분석하였다. 연구 결과 TTCT 도형 검사는 창의성 수준(level)뿐만 아니 라 창의성 유형 즉 적응적 유형과 혁신적 유형의 2가지로 분류할 수 있었다. 창의성 유형 비 율을 보면 지역별, 학년별, 성별에 관계없이 적응적 유형이 혁신적 유형보다 많았다. 지역별 의 경우 대도시일수록 적응적 유형이 많고 읍면지역일수록 혁신적 유형이 많았으며 학년일 경우 6학년은 적응적 유형이 많았고 5학년은 혁신적 유형이 많았다. 성별일 경우 여학생은 적응적 유형이 남학생은 혁신적 유형이 많았다. 적응적 유형일 경우 여학생이 남학생보다 유 의미하게 높았으며 혁신적 유형일 경우 유의미하지 않았지만 여학생이 남학생보다 높게 나타 나 여학생이 남학생보다 창의성 수준이 높게 나타났다. 창의성 유형 분석을 통해 개인의 강 점과 제한점을 알고 참여도를 높일 수 있을 것이다. The purpose of this study is to examine creativity styles of elementary science gifted students through the Torrance Tests of Creative Thinking (TTCT). For this study, the TTCT-Figural Form A was used, with data form 206 elementary science gifted students, which included 56 urban students, 115 suburban students, and 35 rural students. Confirmatory factor analyses were conducted to examine a two-factor model of creativity styles based on Kim’s (2006). Level of creativity was analyzed on the basis of the creativity styles and the numbers of creativity styles were analyzed according to region, grade, and gender. The results are as follows: Factor innovative was loaded by fluency and originality; factor adaptive loaded by elaboration, abstractness of titles, and creative strength; and both factor innovative and factor adaptive loaded by resistance to premature closure. The percentage of adaptive styles is higher than the innovative styles. Urban had more adaptors than rural. There were more adaptors in 6th grade than 5th grade. Gifted female adaptors had significantly higher creative potential than gifted male adaptors and gifted female innovators also showed higher creative potential than gifted male innovators. Creativity styles can give more information about individuals' strengths and weakness so that do an important role in understanding characteristics of gifted students.

      • Accurate Prediction of Available Battery Time for Mobile Applications

        Kim, Dongwon,Chon, Yohan,Jung, Wonwoo,Kim, Yungeun,Cha, Hojung Association for Computing Machinery 2016 ACM transactions on embedded computing systems Vol.15 No.3

        <P>Energy consumption in mobile devices is an important issue for both system developers and users. Users are aware of the battery-related information of their mobile devices and tend to take appropriate actions to increase the battery life. In this article, we propose a framework that accurately estimates the remaining battery time of applications at runtime. The framework profiles the power behavior of applications tied with activated hardware components and estimates the remaining battery budget utilizing the battery-related data provided by the device. The experiments validate that our method predicts the remaining battery time for applications with approximately 93% of accuracy.</P>

      • A Novel Combination Treatment of Armed Oncolytic Adenovirus Expressing IL-12 and GM-CSF with Radiotherapy in Murine Hepatocarcinoma

        KIM, Wonwoo,SEONG, Jinsil,OH, Hae Jin,KOOM, Woong Sub,CHOI, Kyung-Joo,YUN, Chae-Ok Journal of Radiation Research Editorial Committee 2011 Journal of radiation research Vol.52 No.5

        <P>In this study, a novel combination treatment of armed oncolytic adenovirus expressing interleukin 12 (IL-12) and granulocyte-macrophage colony-stimulating factor (GM-CSF) with radiation was investigated for antitumor and antimetastatic effect in a murine hepatic cancer (HCa-I) model. Tumor bearing syngeneic mice were treated with radiation, armed oncolytic virus Ad-ΔE1Bmt7 (dB7) expressing both IL-12 and GM-CSF (armed dB7), or a combination of both. The adenovirus was administered by intratumoral injection 1 × 10<SUP>8</SUP> PFU per tumor in 50 μl of PBS four times every other day. Tumor response to treatment was determined by a tumor growth delay assay. Metastatic potential was evaluated by a lung metastasis model. To understand the underlying mechanism, the level of apoptosis was examined as well as the change in microvessel density and expression of immunological markers: CD4+, CD8+ and Cd11c. The combination of armed dB7 and radiation resulted in significant growth delay of murine hepatic cancer, HCa-1, with an enhancement factor of 4.3. The combination treatment also resulted in significant suppression of lung metastasis. Increase of apoptosis level as well as decrease of microvessel density was shown in the combination treatment, suggesting an underlying mechanism for the enhancement of antitumor effect. Expression of immunological markers: CD4+, CD8+ and Cd11c also increased in the combination treatment. This study showed that a novel combination treatment of radiotherapy with armed oncolytic adenovirus expressing IL-12 and GM-CSF was effective in suppressing primary tumor growth.</P>

      • SCIESCOPUS
      • Development of a hybrid treatment system for combined sewer overflows using a hydrocyclone and a dissolved air flotation system

        Kim, Wonwoo,Maeng, Minsoo,Myung, Gyunam,Lee, Haegyun,Dockko, Seok Informa UK (Taylor Francis) 2016 Desalination and water treatment Vol.57 No.17

        <P>Combined sewer overflows (CSOs) contain a mixture of untreated, contaminated sanitary, and storm water. CSOs include both precipitated and suspended matters. In this study, a novel system is proposed to treat CSOs using a combined hydrocyclone and dissolved air flotation (DAF) system for removal of both precipitated and suspended matter. The optimum operating conditions were determined by changing the internal flow rate and the split ratio (R-f) in the hydrocyclone and by changing the angle of the nozzle to determine the floc size, flow rate, and recycle ratio in the DAF system. The types of organic matter contained in prepared synthetic water samples are categorized as soluble CODcr (SCOD) and particulated CODcr (PCOD) in the characterization of the removal rate of the precipitated and suspended matter. The suspended solids (SS) were classified by their specific gravity to determine the removal rate of both precipitated and suspended matter. In a pretreatment process, the system employed a cationic polymer to obtain a low gradient time (G x t) value. The results showed that poly-aluminum chloride (PAC) used with the cationic polymer had a 9.2% higher turbidity removal rate than PAC alone, due to a stable floc being achieved in the hydrocyclone. The optimum operating conditions of the hydrocyclone showed the highest efficiency at R-f = 10% at a flow rate of 2.8 m/s; the DAF-treated solutions showed a higher removal rate for SCOD solutions vs. PCOD solutions, with the highest turbidity removal rate of 65%. In contrast, when the hydrocyclone-treated solutions had a higher PCOD than SCOD, they showed a higher removal efficiency. The removal rates of SS, CODcr, turbidity, T-P, and T-N of the total process were 77, 80, 98, 98, and 45%, respectively.</P>

      • SCOPUS
      • SCOPUSKCI등재

        Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery

        Kim, Mi-Sook,Kim, Wonwoo,Park, In Hwan,Kim, Hee Jong,Lee, Eunjin,Jung, Jae-Hoon,Cho, Lawrence Chinsoo,Song, Chang W. The Korean Society for Radiation Oncology 2015 Radiation Oncology Journal Vol.33 No.4

        Despite the increasing use of stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS) in recent years, the biological base of these high-dose hypo-fractionated radiotherapy modalities has been elusive. Given that most human tumors contain radioresistant hypoxic tumor cells, the radiobiological principles for the conventional multiple-fractionated radiotherapy cannot account for the high efficacy of SBRT and SRS. Recent emerging evidence strongly indicates that SBRT and SRS not only directly kill tumor cells, but also destroy the tumor vascular beds, thereby deteriorating intratumor microenvironment leading to indirect tumor cell death. Furthermore, indications are that the massive release of tumor antigens from the tumor cells directly and indirectly killed by SBRT and SRS stimulate anti-tumor immunity, thereby suppressing recurrence and metastatic tumor growth. The reoxygenation, repair, repopulation, and redistribution, which are important components in the response of tumors to conventional fractionated radiotherapy, play relatively little role in SBRT and SRS. The linear-quadratic model, which accounts for only direct cell death has been suggested to overestimate the cell death by high dose per fraction irradiation. However, the model may in some clinical cases incidentally do not overestimate total cell death because high-dose irradiation causes additional cell death through indirect mechanisms. For the improvement of the efficacy of SBRT and SRS, further investigation is warranted to gain detailed insights into the mechanisms underlying the SBRT and SRS.

      • SCISCIESCOPUS

        Enhancement of Tumor Radioresponse by Wortmannin in C3H/HeJ Hepatocarcinoma

        KIM, Wonwoo,SEONG, Jinsil,AN, Jung Hee,OH, Hae Jin Journal of Radiation Research Editorial Committee 2007 JOURNAL OF RADIATION RESEARCH Vol.48 No.3

        <P>The objective of this study was to explore whether a specific inhibitor of PI3K, wortmannin, could potentiate the antitumor effect of radiation <I>in vivo</I>, particularly on radioresistant murine tumors. C3H/HeJ mice bearing syngeneic hepatocarcinoma (HCa-I) were treated with 25 Gy radiation, wortmannin, or both. Wortmannin was administered intraperitoneally (1 mg/kg) once daily for 14 days. Tumor response to treatment was determined by a tumor growth delay assay. Possible mechanisms of action were explored by examining the level of apoptosis and regulating molecules. The expression of regulating molecules was analyzed by Western blot for p53 and p21<SUP>WAF1/CIP1</SUP>, and immunohistochemical staining for p21<SUP>WAF1/CIP1</SUP>, CD31 and VEGF. In the tumor growth delay assay, wortmannin increased the effect of tumor radioresponse with an enhancement factor (EF) of 2.00. The level of apoptosis achieved by the combined treatments was shown to be no more than an additive effect; peak apoptotic index was 11% in radiation alone, 13% in wortmannin alone, and 19% in the combination group. Markedly increased areas of necrosis at 24 h in the combination group were noted. Western blotting showed upregulation of p21<SUP>WAF1/CIP1</SUP> in the combination treatment group, which correlated with low levels of VEGF. Microvascular density was evidently also reduced, based on low expression of CD31. In murine hepatocarcinoma, the antitumor effect of radiation was potentiated by wortmannin. The mechanism seems to involve not only the increase of induced apoptosis but also enhanced vascular injury. Wortmannin, in combination with radiation therapy, may have potential benefits in cancer treatment.</P>

      • SCISCIESCOPUS

        Flexibility of Inorganic Tennis Ball Structures Inducing Anion Selectivity

        Kim, Ki-Hyun,Park, Jung Su,Kang, Tae Yi,Oh, Kyungeun,Seo, Mi-Sook,Sohn, Youn Soo,Jun, Moo-Jin,Nam, Wonwoo,Kim, Kwan Mook WILEY-VCH Verlag 2006 Chemistry Vol.12 No.27

        <P>Inorganic tennis balls (ITBs), [[{Pt(betmp)(dach)}<SUB>2</SUB>Cu]<SUB>2</SUB>(X)][X]<SUB>3</SUB> (in which X=ClO<SUB>4</SUB><SUP>−</SUP> (3), NO<SUB>3</SUB><SUP>−</SUP> (4), Cl<SUP>−</SUP> (5) and Br<SUP>−</SUP> (6); dach=trans-1,2-diaminocyclohexane and betmp=bisethylthiomethylidenepropanedioate) and [[{Pt(dteym)(dach)}<SUB>2</SUB>Cu]<SUB>2</SUB>(PF<SUB>6</SUB>)][PF<SUB>6</SUB>]<SUB>3</SUB> (7; dteym=1,3-dithiepane-2-ylidenemalonate), were prepared as crystals. Investigation of their X-ray crystal structures revealed that shapes of the cavities in ITBs show significant distortions that depend on the properties of the encapsulated anions. The Cu⋅⋅⋅Cu* distance was observed to be longest in 7 and shortest in 5, the difference between them being 2.05 Å. The flexibility of cavity structures of ITBs makes it possible to encapsulate various anions inside the cavity, while their distortions may be a reason for the difference in the encapsulating ability for anions, that is, anion selectivity. Especially, the distortions observed in 7 are so severe that the encapsulating ability of the cavity for PF<SUB>6</SUB><SUP>−</SUP> is very low compared to other anions. The shapes of ITBs with ClO<SUB>4</SUB><SUP>−</SUP> and BF<SUB>4</SUB><SUP>−</SUP> ions inside their cavities are very similar; however, ClO<SUB>4</SUB><SUP>−</SUP> is encapsulated by the cavity better than BF<SUB>4</SUB><SUP>−</SUP>, which is explicable by the difference of metal–anion interactions. This structural study on ITBs gives a clue to the origin of the anion selectivity of the cavity in ITBs previously investigated by <SUP>19</SUP>F NMR spectroscopy of the ITBs in methanol.</P> <B>Graphic Abstract</B> <P>Anions for tennis! Inorganic tennis balls (ITB) have been studied both in solution and the solid state. The cavity in an ITB is flexible and encapsulates various anions selectively. An example is shown here. <img src='wiley_img/09476539-2006-12-27-CHEM200501626-content.gif' alt='wiley_img/09476539-2006-12-27-CHEM200501626-content'> </P>

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