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Keita Odashiro,Kazuyuki Saito,Takeshi Arita,Toru Maruyama,Takehiko Fujino,Koichi Akashi 대한고혈압학회 2015 Clinical Hypertension Vol.21 No.19
Introduction: Hypertension is associated with microcirculatory disturbance, and erythrocyte deformability is a major determinant of the microcirculation. However, impairment of erythrocyte deformability in hypertensive patients in relation to antihypertensive treatment is unclear. The present study aimed to investigate this impairment in hypertensive patients under treatment using a highly sensitive and quantitative nickel mesh filtration technique. Methods: Deformability was evaluated by filterability, defined as the flow rate of a hematocrit-adjusted erythrocyte suspension relative to that of saline under a specific filtration pressure in a pressure-flow curve obtained by continuous filtration. Baseline characteristics of hypertensive patients (n = 101) and age-matched normotensive subjects (n = 14) were obtained from medical records, and diabetic patients were excluded. Results: Erythrocyte deformability in the hypertensive group was significantly (p = 0.010) lower (87.8 ± 2.2 %) than that of the normotensive group (89.4 ± 1.7 %) and inversely proportional (r = −0.303, p = 0.002) to the mean blood pressure (BP) measured on blood sampling for the filtration study. Stepwise multiple regression analysis demonstrated that this impairment was mostly attributable to the mean BP (p = 0.001), whereas current smoking and episodes of stroke or coronary artery disease were not contributors. Discussion: These findings indicate that erythrocyte deformability is impaired in the hypertensive patients, which depends on the current BP control rather than target organ damage.
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Daiki OKA,Keita FUJINO,Koichiro TANAKA 대한전자공학회 2015 ITC-CSCC :International Technical Conference on Ci Vol.2015 No.6
This paper describes the experimental production of indoor map applications of the building at our campus using multiple iBeacons. Beacon is equipped with BLE (Bluetooth Low Energy) and is the equipment parallel with the standard of iBeacon. In this paper are displayed in the indoor map application acquires location information inside the building by using the beacon. It is common to use the three points method to acquire the location information in the building. However, the authors thought whether you wii not acquire location information in a beacon stand from easy cost side and management. It is difficult because the value of RSSI (Received Signal Strength Indicator) is not stable to acquire the location information a beacon. Therefore, the authors measured RSSI using beacons. Consequently, precision improved more than the case when location information was acquired in a beacon by removing the unnecessary data which sometimes occurs. In this paper is acquire RSSI of beacons, indoor map application displays the present location to a map. As a result, the authors was able to develop the map application that will be display location information using beacons.
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