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RISS 인기검색어
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- 저자 : Keiji Fukuda (검색결과 3 건)
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Keiji Yokoyama,Ryo Yamauchi,Kumiko Shibata,Hiromi Fukuda,Hideo Kunimoto,Kazuhide Takata,Takashi Tanaka,Shinjiro Inomata,Daisuke Morihara,Yasuaki Takeyama,Satoshi Shakado,Shotaro Sakisaka 대한간학회 2019 Clinical and Molecular Hepatology(대한간학회지) Vol.25 No.2
Background/Aims: There is a controversy about the availability of invasive treatment for esophageal/gastric varices in patients with Child-Pugh class C (CP-C) end-stage liver cirrhosis (LC). We have evaluated the validity of invasive treatment with CP-C end-stage LC patients. Methods: The study enrolled 51 patients with CP-C end-stage LC who had undergone invasive treatment. The treatment modalities included endoscopic variceal ligation in 22 patients, endoscopic injection sclerotherapy in 17 patients, and balloon-occluded retrograde transvenous obliteration (BRTO) in 12 patients. We have investigated the overall survival (OS) rates and risk factors that contributed to death within one year after treatment. Results: The OS rate in all patients at one, three, and five years was 72.6%, 30.2%, and 15.1%, respectively. The OS rate in patients who received endoscopic treatment and the BRTO group at one, three, and five years was 67.6%, 28.2% and 14.1% and 90.0%, 36.0% and 18.0%, respectively. The average of Child-Pugh scores (CPS) from before treatment to one month after variceal treatment significantly improved from 10.53 to 10.02 (P=0.003). Three significant factors that contributed to death within one year after treatment included the presence of bleeding varices, high CPS (≥11), and high serum total bilirubin levels (≥4.0 mg/dL). Conclusions: The study demonstrated that patients with a CPS of up to 10 and less than 4.0 mg/dL of serum total bilirubin levels may not have a negative impact on prognosis after invasive treatment for esophageal/gastric varices despite their CP-C end-stage LC.
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Takaki Imai,Masafumi Gotoh,Keiji Fukuda,Misa Ogino,Hidehiro Nakamura,Hiroki Ohzono,Naoto Shiba,Takahiro Okawa 대한견주관절의학회 2021 대한견주관절의학회지 Vol.24 No.2
Background: Complex regional pain syndrome (CRPS)-related hand lesions are one of the complications following arthroscopic rotator cuff repair (ARCR). This study aimed to investigate the clinical outcomes of patients with CRPS-related hand lesions following ARCR. Methods: Altogether, 103 patients with ARCR were included in this study (mean age, 63.6±8.2 years; 66 males and 37 females; follow-up period, preoperative to 12 months postoperative). Clinical assessment included the Japanese Orthopaedic Association (JOA) score, University of California, Los Angeles (UCLA) score, Constant score, 36-item short form health survey (SF-36) score, and Quick Disabilities of the Arm, Shoulder, and Hand (QuickDASH) score from preoperative to 12 months postoperatively. The patients were either assigned to the CRPS group or non-CRPS group depending on CRPS diagnosis until the final follow-up, and clinical outcomes were then compared between the groups. Results: Of 103 patients, 20 (19.4%) had CRPS-related hand lesions that developed entirely within 2 months postoperatively. Both groups showed significant improvement in JOA, UCLA, and Constant scores preoperatively to 12 months postoperatively (p<001). Comparisons between the two groups were not significantly different, except for SF-36 “general health perception” (p<0.05) at 12 months postoperatively. At final follow-up, three patients had residual CRPS-related hand lesions with limited range of motion and finger edema. Conclusions: CRPS-related hand lesions developed in 19.4% of patients following ARCR. Shoulder or upper-limb function improved in most cases at 12 months, with satisfactory SF-36 patient-based evaluation results. Patients with residual CRPS-related hand lesions at the last follow-up require long-term follow-up.
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Takahiro Nagata,Sadahiro Funakoshi,Daisuke Morihara,Satoshi Shakado,Keiji Yokoyama,Kazuhide Takata,Takashi Tanaka,Atsushi Fukunaga,Ryo Yamauchi,Hiromi Fukuda,Hiroki Matsuoka,So Imakiire,Hideto Sakisak 대한장연구학회 2023 Intestinal Research Vol.21 No.4
Background/Aims: The frequency and details of nonalcoholic fatty liver disease (NAFLD) complications in patients with inflammatory bowel disease (IBD) remain unclear. This study aimed to clarify characteristics of NAFLD in patients with IBD.Methods: We retrospectively identified and enrolled patients with IBD diagnosed with or without NAFLD by undergoing abdominal computed tomography (CT) at our institution between 2005 and 2020. The primary endpoint was the complication rate of NAFLD in patients with IBD. Secondary endpoints were the clinical characteristics of nonobese patients with IBD and comorbid NAFLD and their association with nutritional and inflammatory parameters.Results: Twenty-one (21.9%) of 96 eligible patients with IBD also had NAFLD. In nonobese patients (defined as patients with a body mass index <25 kg/m<sup>2</sup>), C-reactive protein (CRP; <i>P</i><0.001) and alanine aminotransferase (<i>P</i>=0.018) levels were higher and the albumin level (<i>P</i>=0.005) and prognostic nutritional index (PNI; <i>P</i>=0.002) values were lower in patients with NAFLD than in those without NAFLD. The PNI value was positively correlated (<i>P</i><0.001) and the CRP level was negatively correlated (<i>P</i>=0.001) with the hepatosplenic ratio. However, in the NAFLD combined group, PNI (<i>P</i><0.05) and CRP values (<i>P</i><0.001) were improved over time after CT imaging by continuing IBD treatment.Conclusions: Worsening nutritional and inflammatory status in IBD patients is associated with complications of NAFLD. Diagnosis of NAFLD in IBD patients using CT imaging might be useful not only for early detection of NAFLD but also in assessing the need for therapeutic intervention for IBD.
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