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RISS 인기검색어
- 검색키워드
- 저자 : Kairong Wang (검색결과 4 건)
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Combinatorial patterns of histone acetylations and methylations in the human genome
Wang, Zhibin,Zang, Chongzhi,Rosenfeld, Jeffrey A,Schones, Dustin E,Barski, Artem,Cuddapah, Suresh,Cui, Kairong,Roh, Tae-Young,Peng, Weiqun,Zhang, Michael Q,Zhao, Keji Nature Publishing Group 2008 Nature genetics Vol.40 No.7
Histones are characterized by numerous posttranslational modifications that influence gene transcription. However, because of the lack of global distribution data in higher eukaryotic systems, the extent to which gene-specific combinatorial patterns of histone modifications exist remains to be determined. Here, we report the patterns derived from the analysis of 39 histone modifications in human CD4<SUP>+</SUP> T cells. Our data indicate that a large number of patterns are associated with promoters and enhancers. In particular, we identify a common modification module consisting of 17 modifications detected at 3,286 promoters. These modifications tend to colocalize in the genome and correlate with each other at an individual nucleosome level. Genes associated with this module tend to have higher expression, and addition of more modifications to this module is associated with further increased expression. Our data suggest that these histone modifications may act cooperatively to prepare chromatin for transcriptional activation.
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A new cable force identification method considering cable flexural rigidity
Wang, Long,Wu, Bo,Gao, Junyue,Shi, Kairong,Pan, Wenzhi,He, Zhuoyi,Ruan, Zhijian,Lin, Quanpan 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.68 No.2
Cables are the main load-bearing members of prestressed structure and other tensegrity structures. Based on the static equilibrium principle, a new cable force identification method considering cable flexural rigidity is proposed. Its computational formula is derived and the strategy to solve its implicit formula is introduced as well. In order to improve the reliability and practicality of this method, the influence of the cable flexural rigidity on cable force identification accuracy is also investigated. Through cable force identification experiments, the relationships among certain parameters including jacking force, jacking displacement, initial cable force, and sectional area (flexural rigidity) are studied. The results show that the cable force calculated by the proposed method considering flexural rigidity is in good agreement with the finite element results and experimental results. The proposed method with high computational accuracy and resolution efficiency can avoid the influences of the boundary condition and the length of the cable on calculation accuracy and is proven to be conveniently applied to cable force identification in practice.
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A new cable force identification method considering cable flexural rigidity
Long Wang,Bo Wu,Junyue Gao,Kairong Shi,Wenzhi Pan,Zhuoyi He,Zhijian Ruan,Quanpan Lin 국제구조공학회 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.68 No.2
Cables are the main load-bearing members of prestressed structure and other tensegrity structures. Based on the static equilibrium principle, a new cable force identification method considering cable flexural rigidity is proposed. Its computational formula is derived and the strategy to solve its implicit formula is introduced as well. In order to improve the reliability and practicality of this method, the influence of the cable flexural rigidity on cable force identification accuracy is also investigated. Through cable force identification experiments, the relationships among certain parameters including jacking force, jacking displacement, initial cable force, and sectional area (flexural rigidity) are studied. The results show that the cable force calculated by the proposed method considering flexural rigidity is in good agreement with the finite element results and experimental results. The proposed method with high computational accuracy and resolution efficiency can avoid the influences of the boundary condition and the length of the cable on calculation accuracy and is proven to be conveniently applied to cable force identification in practice.
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Yan Li,Ningning Song,Kairong Wang 한국화학공학회 2019 Korean Journal of Chemical Engineering Vol.36 No.5
A novel graphene/biochar composite (BG composite) was synthesized by mixing graphene (Gr) onto feedstock biomass followed by slow pyrolysis. The composite was then tested for its sorption capacity of Cd from aqueous solutions. Structure and morphology analysis showed that graphene was coated on the biochar surface, resulting in a larger surface area, more functional groups, greater thermal stability, and higher removal efficiency of Cd in comparison to unmodified biochar. The sorption capacity of the BG composite for Cd was 1.26-2.36 times that of biochar. A pseudo second-order model adequately simulated sorption kinetics. The sorption isotherms were simulated well by Langmuir models, and calculated maximum Cd adsorption capacities did not change significantly with increasing temperature. Thermodynamic parameters showed that the sorption process of Cd onto the BG composite was feasible and spontaneous. The results of the adsorption experiments, as well as the characteristics of biochar, demonstrate that the process of Cd adsorption on BG composites is mainly physical adsorption accompanied by other chemical adsorption phenomena, such as complexation and ion exchange. This study highlights the use of a BG composite as a multifunctional adsorbent for the efficient, economic, and environmentally friendly treatment of pollutants.
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