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      • KCI등재

        Design of a Light and Small Dual-band Airborne Despun Optical System

        Luqing Zhang,Ning Zhang,Xiping Xu,Kailin Zhang,Yue Zhang,Jiachong Li 한국광학회 2024 Current Optics and Photonics Vol.8 No.1

        In aerial cameras, image quality is easily affected by weather, temperature, and the attitude of the aircraft. Aiming at this phenomenon, based on the theory of two-step zoom optical systems, a dual-band optical-despun two-step zoom optical system is designed. The system has a small field of view of 2.00° × 1.60°, and a large field of view of 4.00° × 3.20°. In the zoom process, the wavelength range is 0.45– 0.70 μm and 0.75–1.10 μm, and the size of the optical system is 168 mm (L) × 90 mm (W) × 60 mm (H). The overall lens weight is only 170.8 g, which has advantages for miniaturization and light weight. At the Nyquist frequency of 104 lp/mm, the modulation transfer function of the visible-light optical system is more than 0.44, and that of the near-infrared optical system is more than 0.30, both of which havegood imaging quality and tolerance characteristics in the range of −45 to 60 ℃.

      • KCI등재

        Induced Intermediate Mesoderm Combined with Decellularized Kidney Scaffolds for Functional Engineering Kidney

        Jianye Zhang,Kailin Li,Feng Kong,Chao Sun,Denglu Zhang,Xin Yu,Xuesheng Wang,Xian Li,Tongyan Liu,Guangfeng Shao,Yong Guan,Shengtian Zhao 한국조직공학과 재생의학회 2019 조직공학과 재생의학 Vol.16 No.6

        BACKGROUND: Chronic kidney disease is a severe threat to human health with no ideal treatment strategy. Mature mammalian kidneys have a fixed number of nephrons, and regeneration is difficult once they are damaged. For this reason, developing an efficient approach to achieve kidney regeneration is necessary. The technology of the combination of decellularized kidney scaffolds with stem cells has emerged as a new strategy; however, in previous studies, the differentiation of stem cells in decellularized scaffolds was insufficient for functional kidney regeneration, and many problems remain. METHODS: We used 0.5% sodium dodecyl sulfate (SDS) to produce rat kidney decellularized scaffolds, and induce adipose-derived stem cells (ADSCs) into intermediate mesoderm by adding Wnt agonist CHIR99021 and FGF9 in vitro. The characteristics of decellularized scaffolds and intermediate mesoderm induced from adipose–derived stem cells were identified. The scaffolds were recellularized with ADSCs and intermediate mesoderm cells through the renal artery and ureter. After cocultured for 10 days, cells adhesion and differentiation was evaluated. RESULTS: Intermediate mesoderm cells were successfully induced from ADSCs and identified by immunofluorescence and Western blotting assays (OSR1 ? , PAX2 ?). Immunofluorescence showed that intermediate mesoderm cells differentiated into tubular-like (E-CAD ? , GATA3 ?) and podocyte-like (WT1 ?) cells with higher differentiation efficiency than ADSCs in the decellularized scaffolds. Comparatively, this phenomenon was not observed in induced intermediate mesoderm cells cultured in vitro. CONCLUSION: In this study, we demonstrated that intermediate mesoderm cells could be induced from ADSCs and that they could differentiate well after cocultured with decellularized scaffolds.

      • SCIESCOPUSKCI등재

        Modulation Recognition of MIMO Systems Based on Dimensional Interactive Lightweight Network

        Aer, Sileng,Zhang, Xiaolin,Wang, Zhenduo,Wang, Kailin Korean Society for Internet Information 2022 KSII Transactions on Internet and Information Syst Vol.16 No.10

        Automatic modulation recognition is the core algorithm in the field of modulation classification in communication systems. Our investigations show that deep learning (DL) based modulation recognition techniques have achieved effective progress for multiple-input multiple-output (MIMO) systems. However, network complexity is always an additional burden for high-accuracy classifications, which makes it impractical. Therefore, in this paper, we propose a low-complexity dimensional interactive lightweight network (DilNet) for MIMO systems. Specifically, the signals received by different antennas are cooperatively input into the network, and the network calculation amount is reduced through the depth-wise separable convolution. A two-dimensional interactive attention (TDIA) module is designed to extract interactive information of different dimensions, and improve the effectiveness of the cooperation features. In addition, the TDIA module ensures low complexity through compressing the convolution dimension, and the computational burden after inserting TDIA is also acceptable. Finally, the network is trained with a penalized statistical entropy loss function. Simulation results show that compared to existing modulation recognition methods, the proposed DilNet dramatically reduces the model complexity. The dimensional interactive lightweight network trained by penalized statistical entropy also performs better for recognition accuracy in MIMO systems.

      • KCI등재

        Using Pre-Clinical Studies to Explore the Potential Clinical Uses of Exosomes Secreted from Induced Pluripotent Stem Cell-Derived Mesenchymal Stem cells

        Zhou Andrew Kailin,Jou Eric,Lu Victor,Zhang James,Chabra Shirom,Abishek Joshua,Wong Ethan,Zeng Xianwei,Guo Baoqiang 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.6

        Recent studies of exosomes derived from mesenchymal stem cells (MSCs) have indicated high potential clinical applications in many diseases. However, the limited source of MSCs impedes their clinical research and application. Most recently, induced pluripotent stem cells (iPSCs) have become a promising source of MSCs. Exosome therapy based on iPSC-derived MSCs (iMSCs) is a novel technique with much of its therapeutic potential untapped. Compared to MSCs, iMSCs have proved superior in cell proliferation, immunomodulation, generation of exosomes capable of controlling the microenvironment, and bioactive paracrine factor secretion, while also theoretically eliminating the dependence on immunosuppression drugs. The therapeutic effects of iMSC-derived exosomes are explored in many diseases and are best studied in wound healing, cardiovascular disease, and musculoskeletal pathology. It is pertinent clinicians have a strong understanding of stem cell therapy and the latest advances that will eventually translate into clinical practice. In this review, we discuss the various applications of exosomes derived from iMSCs in clinical medicine.

      • KCI등재

        An experimental study on two-phase fl ow resistances and interfacial drag in packed porous beds

        Liangxing Li,Kailin Wang,Shuangbao Zhang,Xianliang Lei 한국원자력학회 2018 Nuclear Engineering and Technology Vol.50 No.6

        Motivated by reducing the uncertainties in quantification of debris bed coolability, this paper reports anexperimental study on two-phase flow resistances and interfacial drag in packed porous beds. The experimentsare performed on the DEBECO-LT (DEbris BEd COolability-Low Temperature) test facilitywhich is constructed to investigate the adiabatic single and two phase flow in porous beds. The pressuredrops are measured when air-water two phase flow passes through the porous beds packed withdifferent size particles, and the effects of interfacial drag are studied especially. The results show that, fortwo phase flow through the beds packed with small size particles such as 1.5 mm and 2 mm spheres, thecontribution of interfacial drag to the pressure drops is weak and ignorable, while the significant effectsare conducted on the pressure drops of the beds with bigger size particles like 3 mm and 6 mm spheres,where the interfacial drag in beds with larger particles will result in a descent-ascent tendency in thepressure drop curves along with the fluid velocity, and the effect of interfacial drag should be consideredin the debris coolability analysis models for beds with bigger size particles.

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