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Kwon, Ohjae,Lee, Jeongjin,Kim, Bohyoung,Shin, Juneseuk,Shin, Yeong-Gil Elsevier 2017 Computers in biology and medicine Vol.82 No.-
<P><B>Abstract</B></P> <P>With the recent advances regarding the acquisition and simulation of blood flow data, blood flow visualization has been widely used in medical imaging for the diagnosis and treatment of pathological vessels. In this paper, we present a novel method for the visualization of the blood flow in vascular structures. The vessel inlet or outlet is first identified using the orthogonality metric between the normal vectors of the flow velocity and vessel surface. Then, seed points are generated on the identified inlet or outlet by Poisson disk sampling. Therefore, it is possible to achieve the automatic seeding that leads to a consistent and faster flow depiction by skipping the manual location of a seeding plane for the initiation of the line integration. In addition, the early terminated line integration in the thin curved vessels is resolved through the adaptive application of the tracing direction that is based on the flow direction at each seed point. Based on the observation that blood flow usually follows the vessel track, the representative flowline for each branch is defined by the vessel centerline. Then, the flowlines are rendered through an opacity assignment according to the similarity between their shape and the vessel centerline. Therefore, the flowlines that are similar to the vessel centerline are shown transparently, while the different ones are shown opaquely. Accordingly, the opacity modulation method enables the flowlines with an unusual flow pattern to appear more noticeable, while the visual clutter and line occlusion are minimized. Finally, Hue-Saturation-Value color coding is employed for the simultaneous exhibition of flow attributes such as local speed and residence time. The experiment results show that the proposed technique is suitable for the depiction of the blood flow in vascular structures. The proposed approach is applicable to many kinds of tubular structures with embedded flow information.</P> <P><B>Highlights</B></P> <P> <UL> <LI> An improved method for visualizing blood flow in vascular structures is proposed. </LI> <LI> The proposed method automates the seeding process. </LI> <LI> Our method resolves the early termination of flowline integration in curved vessels. </LI> <LI> Our method adjusts the visibility of flowlines by attenuating the opacity. </LI> <LI> Our method enables a faster diagnosis through the depiction of abnormal flow. </LI> </UL> </P>
Kwon, Hee-won,Kim, JeongJin,Ha, Dong-Woo,Kim, Young-Hun The Korea Institute of Applied Superconductivity a 2016 한국초전도저온공학회논문지 Vol.18 No.1
There are a few thousand abandoned metal mines in South Korea. The abandoned mines cause several environmental problems including releasing acid mine drainage (AMD), which contain a very high acidity and heavy metal ions such as Fe, Cu, Cd, Pb, and As. Iron oxides can be formed from the AMD by increasing the solution pH and inducing precipitation. Current study focused on the formation of iron oxide in an AMD and used the oxide for adsorption of heavy metals. The heavy metal adsorbed iron oxide was separated with a superconducting magnet. The duration of iron oxide formation affected on the type of mineral and the degree of magnetization. The removal rate of heavy metal by the adsorption process with the formed iron oxide was highly dependent on the type of iron oxide and the solution pH. A high gradient magnetic separation (HGMS) system successfully separated the iron oxide and harmful heavy metals.
Resection Plane-Dependent Error of CT Volumetry for Right Hepatic Lobe in Live Liver Donors
( Heon-ju Kwon ),( Kyoung Won Kim ),( Bohyun Kim ),( So Yeon Kim ),( Jeongjin Lee ),( Gi Won Song ),( Sung Gyu Lee ) 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1
Aims: CT hepatic volumetry is currently accepted as the most reliable method for preoperative assumption of the graft weight for living donor liver transplantation. However, the estimated value from CT volumetry can be deviated from real graft weight due to several factors including the difference between the preoperative assumptive and the actual hepatectomy planes. It may be worthwhile to determine how much each factor contributes to the error of CT volumetry. Thus, the purpose of this study was to determine the resection plane-dependent error of CT volumetry for right hepatic lobe in live liver donors. Methods: Forty-six live liver donors underwent CT scans ≤2 months before the liver procurement and within postoperative day 7. CT volumetry was performed by two radiologists in consensus using a computer-aided liver volumetry software. Prospective CT volumetry (VP) was measured with assumptive hepatectomy plane. Retrospective liver volume (VR) was measured using actual plane determined by comparing preoperative and postoperative CT scans. Compared with intraoperatively measured weight (W), errors of percentage (%) VP and VR were evaluated. Plane-dependent error of VP was defined as absolute difference between VP and VR. % plane-dependent error was defined as follow:|VP-VR|/W·100. Results: Mean VP, VR, and W were 761.9 mL, 755.0 mL, and 696.9g. Mean and % errors of VP were 73.3 mL and 10.7%. Mean error and % error of VR were 64.4 mL and 9.3%. Mean plane-dependent error of VP was 32.4 mL. Mean % plane-dependent error was 4.7%. The plane-dependent error of VP exceeded 10% of W in approximately 10% of the subjects in our study. Conclusions: There is approximately 5% plane-dependent error for VP at CT volumetry. However, even with correction of plane-dependent error, error of VR is still approximately 9% compared with W.
( Heon-ju Kwon ),( Kyoung Won Kim ),( Bohyun Kim ),( So Yeon Kim ),( Chul Seung Lee ),( Jeongjin Lee ),( Gi Won Song ),( Sung Gyu Lee ) 대한간학회 2018 Clinical and Molecular Hepatology(대한간학회지) Vol.24 No.1
Background/Aims: Computed tomography (CT) hepatic volumetry is currently accepted as the most reliable method for preoperative estimation of graft weight in living donor liver transplantation (LDLT). However, several factors can cause inaccuracies in CT volumetry compared to real graft weight. The purpose of this study was to determine the frequency and degree of resection plane-dependent error in CT volumetry of the right hepatic lobe in LDLT. Methods: Forty-six living liver donors underwent CT before donor surgery and on postoperative day 7. Prospective CT volumetry (V< SUB >P< /SUB >) was measured via the assumptive hepatectomy plane. Retrospective liver volume (V< SUB >R< /SUB >) was measured using the actual plane by comparing preoperative and postoperative CT. Compared with intraoperatively measured weight (W), errors in percentage (%) V< SUB >P< /SUB > and V< SUB >R< /SUB > were evaluated. Plane-dependent error in V< SUB >P< /SUB > was defined as the absolute difference between V< SUB >P< /SUB > and V< SUB >R< /SUB >. % plane-dependent error was defined as follows: |V< SUB >P< /SUB >-V< SUB >R< /SUB >|/W·100. Results: Mean V< SUB >P< /SUB >, V< SUB >R< /SUB >, and W were 761.9 mL, 755.0 mL, and 696.9 g. Mean and % errors in V< SUB >P< /SUB > were 73.3 mL and 10.7%. Mean error and % error in V< SUB >R< /SUB > were 64.4 mL and 9.3%. Mean plane-dependent error in V< SUB >P< /SUB > was 32.4 mL. Mean % planedependent error was 4.7%. Plane-dependent error in V< SUB >P< /SUB > exceeded 10% of W in approximately 10% of the subjects in our study. Conclusions: There was approximately 5% plane-dependent error in liver V< SUB >P< /SUB > on CT volumetry. Plane-dependent error in V< SUB >P< /SUB > exceeded 10% of W in approximately 10% of LDLT donors in our study. This error should be considered, especially when CT volumetry is performed by a less experienced operator who is not well acquainted with the donor hepatectomy plane. (Clin Mol Hepatol 2018;24:54-60)
Kim, Taeyoung,Yeo, Jeongjin,Yang, Yoonseok,Kang, Sukwon,Paek, Yee,Kwon, Jin Kyung,Jang, Jae Kyung Elsevier 2019 Journal of Power Sources Vol.410 No.-
<P><B>Abstract</B></P> <P>Microbial fuel cells exhibit low output voltages, which must be enhanced for application in practical electronic devices. However, connecting microbial fuel cells in series for voltage boosting may cause voltage reversal, resulting in energy loss and biofilm damage. In this paper, different configurations for connecting microbial fuel cells and power-management systems are investigated to boost the voltage without reversal. The best configuration of the investigated method is as follows: A single power-management system is connected to a single microbial fuel cell or parallel-connected microbial fuel cells (boosted voltage from <0.2 V to 3.3 V); several such individual power-management systems are then connected in series (increased to 6.6 V using two power-management systems). Interestingly, when the single microbial fuel cell supplies insufficient power (<I>e.g.</I>, activity loss such as fuel starvation) to the power-management system in series, the voltage reversal of a capacitor occurs in the series-connected power-management system, and not in the microbial fuel cell. However, the effects of this voltage reversal are outweighed by the benefits of protecting the microbial fuel cell from failure. This approach can be informative for applications of power-management systems and microbial fuel cells as a power source in practical electronic devices.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Energy is harvested from swine wastewater using MFCs linked with PMSs. </LI> <LI> Parallel connection prevents voltage reversal and reduces energy loss. </LI> <LI> PMS linked to an MFC or MFCs in parallel prevent voltage reversal of MFCs. </LI> <LI> Activity loss of MFC causes voltage reversal of the capacitor of stacked PMSs. </LI> <LI> Kinetic imbalance of MFCs and capacitors cause voltage reversal. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Kim, Ok-Kyung,Lee, Minhee,Kwon, Han Ol,Lee, Dasom,Park, Jeongjin,Kim, Eungpil,You, Yanghee,Lim, Young Tae,Jun, Woojin,Lee, Jeongmin S. Karger AG 2018 Skin pharmacology and physiology Vol.31 No.4
<P>We investigated the potential effects of<I> Costaria costata</I><B><I></I></B> (CC) on atopic dermatitis (AD) development in chloro-2,4-dinitrobenzene (DNCB)-treated NC/Nga mice. CC is a brown alga distributed across the seas of Korea, China, and Japan. A total of 40 mice were randomly assigned to 5 groups with 8 mice per group: untreated Balb/c mice, AD control (0.1% w/v DNCB-treated NC/Nga mice), positive control (i.e., DNCB-treated NC/Nga mice fed a dietary supplement of 66.6 mg/kg of body weight [b.w.] of CJLP133), DNCB-treated NC/Nga mice fed a dietary supplement of 100 mg/kg b.w. of CCE10 (CCE10 100), and DNCB-treated mice fed a dietary supplement of 300 mg/kg b.w. of CCE10 (CCE10 300) groups. The CCE10 100 and CCE10 300 treatment groups suppressed AD development including clinical and histopathological changes and a reduction in skin hydration induced by DNCB. In addition, Th2 cytokine production in primary splenocytes, serum IgE and histamine production, and mast cell infiltration into the skin were suppressed in the CCE10 300 mice compared to the CCE10 100 mice. Our finding demonstrated an inhibitory effect of CCE10 in AD development by means of improving the Th1/Th2 cytokine balance and anti-inflammatory effect in an in vivo model.</P>