Polysomnography and Neuropsychological Analysis of Patients With Post-Traumatic Stress Disorder Two Years After the COVID-19 Pandemic in Wuhan

Junhua Mei,Yanjie Xu,Xue Gong,Jinmei Xu,Guohua Chen,Weiqi Chen,Yicong Wang,Zhaohong Kong,Yilong Wang,Qing Yang 대한신경정신의학회 2024 PSYCHIATRY INVESTIGATION Vol.21 No.3

Objective We used polysomnography (PSG) monitoring and neuropsychological scales to explore the characteristics of coronavirus disease-2019 (COVID-19) patients diagnosed with post-traumatic stress disorder (PTSD) in Wuhan, two years after the onset of the COVID-19 pandemic.Methods A total of 42 patients in the Sleep Medicine Center were diagnosed with insomnia between December 2021 and May 2022; they were divided into the PTSD group (patients with PTSD diagnosed with insomnia after COVID-19 infection) and the non-PTSD group (patients with insomnia without PTSD). A healthy control group was simultaneously included.Results The PTSD group was more significant than the non-PTSD group in partial manifestations of sleep disorders, neuropsychological clinical symptoms, and partial PSG data. Patients with different COVID-19 subtypes showed significant differences in the course of disease, sleep disorders, neuropsychological clinical symptoms, relevant scale scores, and PSG data analysis.Conclusion The emotional anxiety and depression of COVID-19 patients diagnosed with PTSD two years after the COVID-19 pandemic in Wuhan are more significant, and will not be self-alleviated with the passage of time. It is necessary to continue to pay attention to the PTSD symptoms and sleep psychology of COVID-19 infected patients, and take appropriate measures. Patients with severe and critical COVID-19 have more severe sleep and mental disorders, and there is a significant correlation between the duration of the disease and the severity of mental and mental disorders and sleep disorders after recovery.

A New Full-Aperture Reflective Null Measuring Method for Conformal Dome

Xu Dong Yang,Junhua Wang,Min Xu 한국광학회 2016 Current Optics and Photonics Vol.20 No.1

In this paper, a novel full-aperture reflective null measuring method is proposed to detect the transmissionwavefront of a conformal dome surface. An aspheric compensator is designed and placed behind the dometo reflect the aspheric testing wave back to the same path. To ensure the feasibility of this method, toleranceanalysis is conducted, and guidance to assembly is given accordingly. The accuracy of this method isverified to be λ/30 (λ =3.39 μm) by Monte Carlo algorithm. In addition, the influence of different error factors,including the thickness error and decenter error of the dome, on the testing wavefront is analyzed. Simulationand experiment indicate that this method is practical and simple, and can measure the conformal domesprecisely and comprehensively.

Design of a See-through Off-Axis Head-Mounted-Display Optical System with an Ellipsoidal Surface

Junhua Wang,Qing Zhou,Jie Chen,Lexin Hou,Min Xu 한국광학회 2018 Current Optics and Photonics Vol.2 No.3

A new method to design a see-through off-axis head-mounted-display (OA-HMD) optical system with an ellipsoidal surface is proposed, in which a tilted ellipsoidal surface is used as the combiner, which yields the benefits of easier fabrication and testing compared to a freeform surface. Moreover, we realize a coaxial structure in the relay lens group, which is simple and has looser tolerance requirements, thus making assembly easier. The OA-HMD optical system we realize has a simple structure and consists of a combiner and 7 pieces of coaxial relay lenses. It has a 48° × 36° field of view (FOV) and 12-mm exit pupil diameter.

Design of a Low Distortion Head-Mounted Display with Freeform Reflective Mirror Based on Two Ellipsoids Structure

Junhua Wang,Yuechao Liang,Min Xu 한국광학회 2016 Current Optics and Photonics Vol.20 No.2

A new method to design a low distortion, even relative illumination, optical see-through head-mounteddisplay (HMD) with a freeform reflective mirror (FFRM) based on the two similar ellipsoids structureis proposed. The HMD we have realized has a simple structure which consists of two similar ellipsoidsurfaces, an FFRM, a 7-piece co-axis relay lens, and an OLED. This structure can be applied to offsetdistortion, reach even relative illumination, and correct the off-axis aberrations. The HMD we finally haverealized has a near 3% low distortion, a higher than 80% relative illumination, and a 40°×30° field ofview (FOV).

Design of a See-Through Head-Mounted Display with a Freeform Surface

Junhua Wang,Min Xu,Yuechao Liang 한국광학회 2015 Current Optics and Photonics Vol.19 No.6

This paper described an off-axis head-mounted display system. It is composed of a 7-piece coaxial relaylens group and a freeform surface combiner. This configuration has a simple structure and a wide fieldof view (FOV). In this design, a freeform surface is chosen as the combiner, to simplify the structureand attain good image quality. We generated this freeform surface by considering both coordinates andnormals of discrete data points. Moreover, we realize a coaxial structure in the relay lens group, whichis compact and benefits from a loose tolerance requirement. The HMD system we finally realized hasa 40° × 30° FOV and 15-mm exit pupil diameter

Distributed Event-triggered Consensus Control for Heterogeneous Multiagent Systems under Fixed and Switching Topologies

Junhua Huang,Liding Chen,Xuhuan Xie,Mufeng Wang,Bugong Xu 제어·로봇·시스템학회 2019 International Journal of Control, Automation, and Vol.17 No.8

This paper investigates the distributed consensus problem for heterogeneous multi-agent systems via event-triggered scheme. To alleviate the communication burden, a distributed event-triggered consensus algorithm using an open-loo estimate and neighboring information is proposed. In the proposed event-triggered scheme, the control input of each agent is dependent on the estimate and information at discrete instants. Firstly, the novel event-triggered consensus algorithm is proposed for fixed topology, which involves the discrete communication between neighboring agents. Then, for the switching topology, the triggering condition is proposed by virtue of a topology-dependent dwell time approach. Further, the corresponding consensus procedures are given. Finally, the effectiveness of the proposed scheme is illustrated by numerical results.

A Novel Electrochemical Method for Sensitive Detection of Melamine in Infant Formula and Milk using Ascorbic Acid as Recognition Element

Junhua Li,Daizhi Kuang,Yonglan Feng,Fuxing Zhang,Zhifeng Xu,Mengqin Liu 대한화학회 2012 Bulletin of the Korean Chemical Society Vol.33 No.8

A novel and convenient electrochemical method has been developed for sensitive determination of melamine (MEL) using ascorbic acid (AA) as the recognition element. The working electrode employed in this method was modified with the nanocomposite of hydroxyapatite/carbon nanotubes to enhance the current signal of recognition element. The interaction between MEL and AA was investigated by fourier transform infrared spectroscopy and cyclic voltammetry, and the experimental results indicated that hydrogen bonding was formed between MEL and AA. Because of the existing hydrogen bonding and electrostatic interaction, the anodic peak current of AA was decreased obviously while the non-electroactive MEL added in. It illustrated that the MEL acted as an inhibitor to the oxidation of AA and the decreasing signals can be used to detect MEL. Under the optimal conditions, the decrease in anodic peak current of AA was proportional to the MEL concentrations ranging from 10 to 350 nM, with a detection limit of 1.5 nM. Finally this newly-proposed method was successfully employed to detect MEL in infant formula and milk, and good recovery was achieved.

A Novel Electrochemical Method for Sensitive Detection of Melamine in Infant Formula and Milk using Ascorbic Acid as Recognition Element

Li, Junhua,Kuang, Daizhi,Feng, Yonglan,Zhang, Fuxing,Xu, Zhifeng,Liu, Mengqin Korean Chemical Society 2012 Bulletin of the Korean Chemical Society Vol.33 No.8

A novel and convenient electrochemical method has been developed for sensitive determination of melamine (MEL) using ascorbic acid (AA) as the recognition element. The working electrode employed in this method was modified with the nanocomposite of hydroxyapatite/carbon nanotubes to enhance the current signal of recognition element. The interaction between MEL and AA was investigated by fourier transform infrared spectroscopy and cyclic voltammetry, and the experimental results indicated that hydrogen bonding was formed between MEL and AA. Because of the existing hydrogen bonding and electrostatic interaction, the anodic peak current of AA was decreased obviously while the non-electroactive MEL added in. It illustrated that the MEL acted as an inhibitor to the oxidation of AA and the decreasing signals can be used to detect MEL. Under the optimal conditions, the decrease in anodic peak current of AA was proportional to the MEL concentrations ranging from 10 to 350 nM, with a detection limit of 1.5 nM. Finally this newly-proposed method was successfully employed to detect MEL in infant formula and milk, and good recovery was achieved.

Conserved Sequences of Replicase Gene-Mediated Resistance to Potyvirus through RNA Silencing

Li Xu,YunZhi Song,JunHua Zhu,XingQi Guo,ChangXiang Zhu,FuJiang Wen 한국식물학회 2009 Journal of Plant Biology Vol.52 No.6

Nuclear inclusion protein b (NIb) genes of three Potato virus Y isolates PVY-SD1 (O strain), PVY-SD4 (N strain), PVY-SD5 (NTN strain), and Tobacco etch virus isolate TEV-SD1 in Shandong Province were cloned and sequenced. Sequence analysis showed that the sequence homology of the entire NIb gene among the four viruses ranged from 65% to 95%. Hairpin RNA (hpRNA) constructs were designed based on five conserved regions derived from PVY-SD1 and introduced into tobacco plants. After asexual propagation, the transgenic plants were analyzed for resistance to PVY-SD1, PVY-SD4, PVY-SD5, and TEV-SD1. We obtained resistance ratios of 26.2%, 22.7%, 36.4%, 20.3%, and 21.7% to PVY-SD1. When inoculated with the PVY-SD5 virus, the transgenic plants had resistance ratios ranging from 2.4% to 15.9%, but no resistance at all to the other viruses, PVY-SD4 and TEV-SD1. No correlation was found between resistance of transgenic plants and the transgene copy numbers. Northern blot and small interfering RNA (siRNA) analysis demonstrated that the resistance was attributable to RNA silencing. Genetic analysis demonstrated that virus resistance was stably inherited in progeny T1 and T2. These results indicate that the siRNA molecules against conserved regions can confer virus resistance but are restricted to viruses with more than 90% sequence homology.

Tex3: An 2R1T Parallel Manipulator with Minimum DOF of Joints and Fixed Linear Actuators

Lingmin Xu,Qinchuan Li,Junhua Tong,Qiaohong Chen 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.2

A new 2R1T (R: rotation, T: translation) parallel manipulator (PM), called Tex3, is proposed. The Tex3 PM is a 2PUR-PRU PM consisting of 9 joints with 12 DOFs (degrees of freedom), and can be actuated by fixed linear actuators. Mobility analysis shows that it is an RPR-equivalent PM whose finite motion is the product of a rotation (R) followed by a translation (P) and another rotation (R). Inverse position and velocity analyses are discussed. Furthermore, the local transmission index and good transmission workspace are used to evaluate the motion/force transmissibility of the proposed PM. The singularity loci of the proposed PM are obtained according to the motion/force transmissibility, corresponding to the inverse, forward and combined kinematic singularity. The constraint singularity is also discussed. Finally, link parameters are optimized to obtain an improved good transmission workspace. Because of its minimum DOF of joints and fixed linear actuators, the Tex3 PM has good kinematic performance and is suited to the high-speed machining of workpieces with curved surfaces.