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      • RIPENING OF SILVER NANOPARTICLES ON CARBON NANOTUBES

        LIYING ZHU,GANHUA LU,SHUN MAO,JUNHONG CHEN,DMITRIY A. DIKIN,XINQI CHEN,로드니루오프 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2007 NANO Vol.2 No.3

        An electrostatic-force-directed-assembly technique was used to coat multiwalled carbon nano-tubes (MWCNTs) with aerosol Ag nanoparticles produced from a mini-arc plasma source. The deposition of Ag nanoparticles onto CNTs was confirmed by transmission electron microscopy (TEM), high-resolution TEM, scanning electron microscopy, and X-ray photoelectron spectroscopy. Ripening of Ag nanoparticles on CNTs was observed via successive TEM imaging after heating the nanoparticle–nanotube hybrid structures in air to three different temperatures ranging from 100°C to 300°C. With temperatures at and above 200°C, the areal density of Ag nanoparticles decreased and the average particle size increased. In particular, migration and coalescence of Ag nanoparticles have been observed at this relatively low temperature, which suggests a van der Waals nanoparticle–nanotube interaction.

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        Boosting photocharge separation in Z-schemed g-C3N4/RGO/ln2S3 photocatalyst for H2 evolution and antibiotic degradation

        Bingrong Guo,Bin Liu,Chaoli Wang,Junhong Lu,Yuhua Wang,Shu Yin,Muhammad Sufyan Javed,Wei-Hua Han 한국공업화학회 2022 Journal of Industrial and Engineering Chemistry Vol.110 No.-

        Due to the high redox ability and effective separation of photocharges, Z-schemed photocatalysts havebeen extensively used to deal with energy crises and environmental pollution. Here, a novel Zschemedg-C3N4/RGO/ln2S3 photocatalyst was designed and prepared for hydrogen generation and tetracyclinehydrochloride degradation. The properties of optical absorption, separation, and transfer of photochargesand heterojunction on photocatalytic activity of g-C3N4/RGO/ln2S3 composite have beenstudied. The characterization results showed that the Z-scheme photocatalyst has high efficiency onthe separation and transfer of photocharges, and the strong redox ability has also remained. Thus, theg-C3N4/RGO/ln2S3 composite exhibited superior photocatalytic performance than pristine ln2S3 and g-C3N4 in the same situations. The H2 evolution rate can reach up to 512.72 lmolg-1h1 and the degradationof tetracycline hydrochloride can reach 95.6% in 60 min under visible light irradiation. This work providesa potential pathway for designing and preparing high-performance photocatalysts to produce cleanenergy and purify the environment.

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        The anti-tumor efficacy of 20(S)-protopanaxadiol, an active metabolite of ginseng, according to fasting on hepatocellular carcinoma

        Wenzhen Li,YifanWang,Xinbo Zhou,Xiaohong Pan,Junhong Lu,Hongliu Sun,Zeping Xie,Shayan Chen,Xue Gao 고려인삼학회 2022 Journal of Ginseng Research Vol.46 No.1

        Background: 20(S)-protopanaxadiol (20(S)-PPD), one of the main active metabolites of ginseng, performs a broad spectrum of anti-tumor effects. Our aims are to search out new strategies to enhance anti-tumor effects of natural products, including 20(S)-PPD. In recent years, fasting has been shown to be multifunctional on tumor progression. Here, the effects of fasting combined with 20(S)-PPD on hepatocellular carcinoma growth, apoptosis, migration, invasion and cell cycle were explored. Methods: CCK-8 assay, trypan blue dye exclusion test, imagings photographed by HoloMonitorTM M4, transwell assay and flow cytometry assay were performed for functional analyses on cell proliferation, morphology, migration, invasion, apoptosis, necrosis and cell cycle. The expressions of genes on protein levels were tested by western blot. Tumor-bearing mice were used to evaluate the effects of intermittent fasting combined with 20(S)-PPD. Results: We firstly confirmed that fasting-mimicking increased the anti-proliferation effect of 20(S)-PPD in human HepG2 cells in vitro. In fasting-mimicking culturing medium, the apoptosis and necrosis induced by 20(S)-PPD increased and more cells were arrested at G0-G1 phase. Meanwhile, invasion and migration of cells were decreased by down-regulating the expressions of matrix metalloproteinase (MMP)-2 and MMP-9 in fasting-mimicking medium. Furthermore, the in vivo study confirmed that intermittent fasting enhanced the tumor growth inhibition of 20(S)-PPD in H22 tumor-bearing mice without obvious side effects. Conclusion: Fasting significantly sensitized HCC cells to 20(S)-PPD in vivo and in vitro. These data indicated that dietary restriction can be one of the potential strategies of chinese medicine or its active metabolites against hepatocellular carcinoma.

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