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RISS 인기검색어
- 검색키워드
- 저자 : Juan Medrano (검색결과 3 건)
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- 유료
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Antioxidant Activity of Collagen Extracts Obtained from the Skin and Gills of Oreochromis sp.
Jose Roberto Medina-Medrano,Tannia Alexandra Quin˜ones-Mun˜oz,Abel Arce-Ortı´z,Juan Gabriel Torruco-Uco,Ricardo Herna´ndez-Martı´nez,Manuel Alejandro Lizardi-Jime´nez,Elizabeth Varela-Santos 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.7
Efforts aimed at reduction of fishing waste generated during the evisceration and filleting are scarce. The fishing waste is used in the production of low value-added products, such as flours or silages. It is important to visualize an alternative and profitable use of this waste, as it constitutes a serious environmental problem. This research determined the antioxidant properties of collagenous extracts of skin and galls of Oreochromis sp. The raw materials were characterized by proximal chemical analysis. Three treatments were applied to extract the collagen: salt-soluble collagen, acid-soluble collagen (ASC), and pepsin-hydrolyzed collagen (PHC). The collagenous fractions were hydrolyzed (0.1% pepsin). The recovered collagen yield and antioxidant activity were determined to hydrolyzed collagen (HC) and nonhydrolyzed collagen (NHC). The ASC skin showed the highest extraction yield (3.02%). For galls, only the PHC extraction was feasible (0.16%). Antioxidant analysis of NHC did not reveal radical scavenging activities. HC displayed a 2,2-diphenyl-1-picrylhydrazyl %RSA of 22.58 (ASC skin) and 10.34% (PHC galls), and a 2,2′-azino-bis[3-ethylbenzothiazoline-6-sulfonic acid] %RSA of 30.40% (PHC skin) and 29.43% (PHC galls), respectively. The ASC skin and PHC gall extracts exhibited 94.40% and 81.54% in ferric-reducing antioxidant power, and 43.63 and 38.08 μg ascorbic acid equivalents per milli liter for total antioxidant capacity, respectively. The collagen extracts showed %RSA and chelation of pro-oxidant metal ions. Different mechanism of antioxidant action was identified for the extracts: radical scavengers for HC and metal ion chelators for NHC. In conclusion, red tilapia skin collagen is recommended as an active ingredient of nutraceuticals, pharmaceuticals, or functional foods, for the identified bioactive properties.
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Minimally Invasive versus Open Surgery for Spinal Metastasis: A Systematic Review and Meta-Analysis
Hinojosa-Gonzalez David Eugenio,Roblesgil-Medrano Andres,Villarreal-Espinosa Juan Bernardo,Tellez-Garcia Eduardo,Bueno-Gutierrez Luis Carlos,Rodriguez-Barreda Jose Ramon,Flores-Villalba Eduardo,Martin 대한척추외과학회 2022 Asian Spine Journal Vol.16 No.4
Bones are the third most common location for solid tumor metastasis affecting up to 10% of patients with solid tumors. When the spine is involved, thoracic and lumbar vertebrae are frequently affected. Access to spinal lesions can be through minimally invasive surgery (MIS) or traditional open surgery (OS). This study aims to determine which method provides an advantage. Following the PRISMA (Preferred Inventory for Systematic Reviews and Meta-Analysis) guidelines, a systematic review was conducted to identify studies that compare MIS with OS in patients with spinal metastatic disease. Data were analyzed using Review Manager ver. 5.3 (RevMan; Cochrane, London, UK). Ten studies were included. Operative time was similar among groups at -35.23 minutes (95% confidence interval [CI], -73.36 to 2.91 minutes; <i>p</i>=0.07). Intraoperative bleeding was lower in MIS at -562.59 mL (95% CI, -776.97 to -348.20 mL; <i>p</i><0.00001). OS procedures had higher odds of requiring blood transfusions at 0.26 (95% CI, 0.15 to 0.45; <i>p</i><0.00001). Both approaches instrumented similar numbers of levels at -0.05 levels (95% CI, -0.75 to 0.66 levels; <i>p</i>=0.89). We observed a decreased need for postoperative bed rest at -1.60 days (95% CI, -2.46 to -0.74 days; <i>p</i>=0.0003), a shorter length of stay at -3.08 days (95% CI, -4.50 to -1.66 days; <i>p</i>=0.001), and decreased odds of complications at 0.60 (95% CI, 0.37 to 0.96; <i>p</i>=0.03) in the MIS group. Both approaches revealed similar reintervention rates at 0.65 (95% CI, 0.15 to 2.84; <i>p</i>=0.57), effective rates of reducing metastasis-related pain at -0.74 (95% CI, -2.41 to 0.94; <i>p</i>=0.39), and comparable scores of the Tokuhashi scale at -0.52 (95% CI, -2.08 to 1.05; <i>p</i>=0.41), Frankel scale at 1.00 (95% CI, 0.60 to 1.68; <i>p</i>=1.0), and American Spinal Injury Association Scale at 0.53 (95% CI, 0.21 to 1.37; <i>p</i>=0.19). MIS appears to provide advantages over OS. Larger and prospective studies should fully detail the role of MIS as a treatment for spine metastasis.
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Nabih Pico,Hong-ryul Jung,Juan Medrano,Meseret Abayebas,Dong Yeop Kim,황정훈,Hyungpil Moon 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.2
The objective of this work is to control a delivery robot equipped with a passive bogie that can successfully climb up steps of various sizes and move on uneven terrain in outdoor environments. The kinematic model of a six-wheel mobile robot is described in detail. Jacobian matrices and inverse kinematics are obtained to get the velocity of each wheel based on the desired velocity of the robot center of mass in conjunction with the terrain information obtained by the onboard sensors according to the contact angle estimation between the wheel and ground. A slip control is implemented based on slip ratio to adjust the wheel velocity when the slip is detected. Simulation and experimental results verify the effectiveness of the approach that enables the robot autonomously climbing up on different steps and uneven terrain.
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