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RISS 인기검색어
- 검색키워드
- 저자 : Jinyan Jiang (검색결과 3 건)
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Effects of Bread Yeast Cell Wall Beta-Glucans on Mice with Loperamide-Induced Constipation
Zhuoyi Chen,SuSu Lin,Yu Jiang,Ling Liu,Jinyan Jiang,Shuting Chen,Yingpeng Tong,Ping Wang 한국식품영양과학회 2019 Journal of medicinal food Vol.22 No.10
Constipation is a common gastrointestinal disorder characterized by changes in intestinal habits. Increasing evidence indicates that long-term use of irritant laxatives causes serious side effects. Meanwhile, more than 50% of patients are dissatisfied with sense of use of non-prescriptional laxatives. β-glucans are natural polysaccharides widely found in yeast, fungus, and plants, which have been reported to exhibit various pharmacological effects. The aim of this study was to characterize the effect of β-glucans extracted from the bread yeast cell wall on loperamide-induced constipation mice. Forty mice were fed with loperamide (10 mg/kg) to make the constipation model and a diet supplemented with 2.5, 5, and 10 mg/kg β-glucan. We assessed the defecation frequency, intestinal transit function of mice, as well as used high-throughput sequencing to analyze the intestinal microbiota composition and functional biological profiles data. Meanwhile, we detected expression of neurotransmitters including acetylcholinesterase, substance P, and serotonin (5-HT) and expression of tight junction protein (TJP) including zonula occludens-1 and mucin-2 in distal colon to characterize the possible molecular mechanisms. β-glucans significantly enhanced intestinal motility and provided a possibility to regulate the expression of neurotransmitters and TJP in mice. The intestinal microecological portion of the treatment group partially recovered and was closer to the normal group. This study showed that β-glucans can influence the intestinal microbiota and restore microecological balance to regulate the express of neurotransmitters and TJP to recover intestinal epithelial mechanical barrier. We suggested that β-glucans could be used as an active nutritional supplement to protect the damaged intestinal barrier and help patients who have constipation complications and dysbiosis.
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Liu, Baoju,Tan, Jinxia,Shi, Jinyan,Liang, Hui,Jiang, Junyi,Yang, Yuanxia Techno-Press 2021 Advances in concrete construction Vol.11 No.3
Due to economic and environmental benefits, increasing the substitution ratio of ordinary cement by industry by-products like fly ash (FA) is one of the best approaches to reduce the impact of the concrete industry on the environment. However, as the substitution rate of FA increases, it will have an adverse impact on the performance of cement-based materials, so the actual substitution rate of FA is limited to around 10-30%. Therefore, in order to increase the early-age strength of high replacement (30-70%) low-calcium ultrafine FA blended cement paste, sodium sulfate and calcium sulfate dihydrate were used to improve the reactivity of FA. The results show that sodium sulfate has a significant enhancement effect on the strength of the composite pastes in the early and late ages, while calcium sulfate dihydrate has only a slight effect in the late ages. The addition of sodium sulfate in the cement-FA blended system can enhance the gain rate of non-evaporation water, and can decrease the Ca(OH)2 content. In addition, when the sulfate chemical activators are added, the ettringite content increases, and the surface of the FA is dissolved and hydrated.
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Effect of cement as mineral filler on the performance development of emulsified asphalt concrete
Liu, Baoju,Wu, Xiang,Shi, Jinyan,Wu, Xiaolong,Jiang, Junyi,Qin, Jiali Techno-Press 2020 Advances in concrete construction Vol.10 No.6
Cold-mixed asphalt mixture is a widely recommended asphalt pavement materials with potentially economic and environmental benefits. Due to the reduction of natural non-renewable mineral resources, powder minerals with similar properties are considered as new mineral fillers in asphalt mixtures. This study explored the feasibility of using cement to replace natural limestone powder (LP) in emulsified asphalt concrete modified by styrene-butadiene styrene copolymer. The experimental tests, including compressive strength, Marshall stability as well as moisture susceptibility test, were used to investigate the mechanical properties, the Marshall stability, flow value, as well as the moisture damage. In addition, the influence of material composition on the performance of asphalt concrete is explained by the microstructure evolution of the pore structure, the interface transition zone (ITZ), and the micromorphology. Due to mineralogical reactivity of cement, its replacement part of LP improved the mechanical properties, Marshall stability, but it will reduce the moisture susceptibility and flow value. This is because with the increase of the cement substitution rate, the pore structure of the asphalt concrete is refined, the width of ITZ becomes smaller, and the microstructure is more compact. In addition, asphalt concrete with a larger nominal particle size (AC-16) has relatively better performance.
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