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- 저자 : Jiahong Xu (검색결과 4 건)
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Insight into the corrosion inhibition property of Artocarpus heterophyllus Lam leaves extract
Jiahong He,Qiang Xu,Guoqiang Li,Qiang Li,Riadh Marzouki,Wenpo Li 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.102 No.-
In this work, the method (water extraction way) was uesd to acquire Artocarpus heterophyllus Lamleaves extract (AHLLE). We refer to the relevant references on the composition of Artocarpus heterophyllusLam leaves and perform Fourier infrared spectroscopy analysis for AHLLE. It can be concluded thatAHLLE contains 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one (DPD), (2R,3R)-2-(2,4-dihydroxyphenyl)-3 ,5,7-trihydroxychroman-4-one (DPT), 3-(4-hydroxyphenyl)acrylic acid (HPT), and5-(6-hydroxybenzofuran-2-yl)benzene-1,3-diol (HBB). Quantum chemical calculations (QCC) data andmolecular dynamics (MD) simulations results show that DPD, DPT, HPT, and HBB all have the potentialof excellent corrosion inhibitors. Scanning electron microscope (SEM) results and atomic force microscope(AFM) test results show that after adding AHLLE to H2SO4 environment, the copper surface is stillcorrespondingly flat. In addition, the results of electrochemical experiments indicate that the AHLLE is500 ppm, the anti-corrosion efficiency obtained from electrochemical impedance spectroscopy datacan reach 97.3%. With the temperature augments to 313 K, the corrosion inhibition nature of AHLLEcan still be maintained to 97%. AHLLE is adsorbed onto the Cu surface and belongs to Langmuir monolayeradsorption.
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Jiahong Zhu,Yingjie Xu,Xiao Feng,Xiao Zhu 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.67 No.-
To get a better understanding of the effect of physicochemical properties and microstructure on SO2 absorption behavior of DESs with different molar ratios of EmimCl and EG (from 2:1 to 1:2), densities (ρ), viscosities (η), speeds of sound (u), refractive indices (nD), and thermal decomposition temperatures (Td) of EmimCl-EG DESs were measured and used to obtain the other derived properties, such as thermal expansion coefficient (αp) and activation energy for viscous flow (Eη). Moreover, FT-IR spectra and in situ variable-temperature NMR spectroscopy were employed to study the microstructures of DESs. Based on physicochemical and spectroscopic properties, the influence of the concentrations of EmimCl on the interactions in DESs was explored to be associated with their SO2 absorption behavior. The results show that the interactions between Emim+ and Cl− of EmimCl is gradually weakening with increasing the concentration of EG in DESs by forming of hydrogen bond interaction of OH⋯Cl−, resulting in a decrease of ρ, η, u, nD, and Td of DESs, and hindering the charge–transfer interaction of SO2 with Cl− and deceasing SO2 capture capacity. Moreover, the SO2 absorption capacity of DESs is proportional to their ρ and Eη, respectively.
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Wei Zhu,Jiahong Liu,Kuanxiang Shi,Fei Qi,Huiping Shen,Zhu Xu,Zhilong Ma 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.9
This paper proposes a three degree-of-freedoms (DOFs) cable-driven parallel robot (CDPR), which is actuated by three groups of parallel cables and tensioned by an elastic telescopic rod with a passive spring. Firstly, the architecture of the robot is briefly illustrated with emphasis on the three parallelogram arrangements of the cables and composition of elastic telescopic rod structure. This robot has larger workspace and greater tension than previous under-constrained CDPRs. Secondly, the kinematic and dynamic models of the robot are established. On this basis, the parameters of the spring installed in the telescopic rod are optimized and determined considering both the acceleration and cable force through using the differential evolution (DE) algorithm. Thirdly, dynamic stability analysis of the robot under impulsive disturbances is performed according to the Gauss principle of least constraint (GPLC). The results of a simulation case show that this robot has better dynamic stability in comparison with conventional under-constraint CDPR because of the presence of the elastic telescopic rod. The measurement results in the workspace are obtained through dynamic simulation. Finally, the experiments are performed based on numerical simulation. The feasibility of the CDPR is verified via the experiments and simulations.
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Therapeutic inhibition of SGK1 suppresses colorectal cancer
Xuchun Liang,Chunling Lan,Guanming Jiao,Wencheng Fu,Xuesha Long,Yu An,Kejin Wang,Jinzhe Zhou,Ting Chen,Yongqin Li,Jiahong Xu,Qi Huang,Bin Xu,Junjie Xiao 생화학분자생물학회 2017 Experimental and molecular medicine Vol.49 No.-
Colorectal cancer (CRC) is one of the leading causes of death worldwide. Thus, the development of new therapeutic targets for CRC treatment is urgently needed. SGK1 is involved in various cellular activities, and its dysregulation can result in multiple cancers. However, little is known about its roles and associated molecular mechanisms in CRC. In present study, we found that SGK1 was highly expressed in tumor tissues compared with peri-tumor samples from CRC patients. In vitro experiments revealed that SGK1 overexpression promoted colonic tumor cell proliferation and migration and inhibited cell apoptosis induced by 5-fluorouracil (5-FU), while SGK1 shRNA and inhibitors showed the inverse effects. Using CRC xenograft mice models, we demonstrated that knockdown or therapeutic inhibition of SGK1 repressed tumor cell proliferation and tumor growth. Moreover, SGK1 inhibitors increased p27 expression and promoted p27 nuclear accumulation in colorectal cancer cells, and p27 siRNAs could attenuate the repression of CRC cell proliferation induced by SGK1 inhibitors. Collectively, SGK1 promotes colorectal cancer development via regulation
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