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Son JeongA,Hyun Seungji,Yu Woo Sik,Jung Joonho,함석진 대한흉부외과학회 2023 Journal of Chest Surgery (J Chest Surg) Vol.56 No.2
Background: Pneumonia caused by severe acute respiratory syndrome coronavirus 2 can cause acute respiratory distress syndrome, often requiring prolonged mechanical ventilation and eventually tracheostomy. Both procedures occur in isolation units where personal protective equipment is needed. Additionally, the high bleeding risk in patients with extracorporeal membrane oxygenation (ECMO) places a great strain on surgeons. We investigated the clinical characteristics and outcomes of percutaneous dilatational tracheostomy (PDT) in patients with coronavirus disease 2019 (COVID-19) supported by ECMO, and compared the outcomes of patients with and without ECMO. Methods: This retrospective, single-center, observational study included patients with severe COVID-19 who underwent elective PDT (n=29) from April 1, 2020, to October 31, 2021. The patients were divided into ECMO and non-ECMO groups. Data were collected from electronic medical records at Ajou University Hospital in Suwon, Korea. Results: Twenty-nine COVID-19 patients underwent PDT (24 men [82.8%] and 5 women [17.2%]; median age, 61 years; range, 26–87 years; interquartile range, 54–71 years). The mean procedure time was 17±10.07 minutes. No clinically or statistically significant difference in procedure time was noted between the ECMO and non-ECMO groups (16.35±7.34 vs. 18.25±13.32, p=0.661). Overall, 12 patients (41.4%) had minor complications; 10 had mild subdermal bleeding from the skin incision, which was resolved with local gauze packing, and 2 (6.9%) had dislodgement. No healthcare provider infection was reported. Conclusion: Our PDT approach is safe for patients and healthcare providers. With bronchoscopy assistance, PDT can be performed quickly and easily even in isolation units and with acceptable risk, regardless of the hypo-coagulable condition of patients on ECMO.
김미랑 ( Mirang Kim ),유정아 ( Jeonga Yu ),배은경 ( Eunkyoung Bae ),석웅 ( Woong Seok ),하범만 ( Beomman Ha ),최병섭 ( Byungseop Choi ) 국군의무사령부 2020 대한군진의학학술지 Vol.51 No.1
Objective; This study aims to check adequacy of current obesity classification in Korea among young male soldiers. Method; We surveyed 316 military personnel who agreed this study with structured questionnaire. They answered voluntarily the questionnaire and also wrote down their data of medical examination, body composition and army physical fitness test. Results; Subjects were classified as by Body Mass Index(BMI): underweight(<18.5) 1, normal(18.5-22.9) 129(40.8%), overweight(23-24.9) 91(28.8%), obese(25-29.9) 78(24.7%), severe obese (30≤) 17(5.4%). Obesity rate was 30.1% by BMI 25, 14.6% by Body fat(25%) and 18.7% by waist cimcumference(90cm), respectively. This classification by BMI presents 87% of sensitivity, 79.6% of specificity based on 25% Body fat. When we analysed BMI ROC curve by Body fat(25%), sensitivity and specificity were 80.4% and 90% at the point of BMI 26.05. Almost two-third(67%) of Overweight group and one-third(30.8%) of Obese group showed more than 45% of muscle ratio. All of them had less than 25% body fat. In the over obese group, there were statistically significant differences when analyzing the abnormality of medical examination and passing the physical fitness test by dividing into 45% muscle ratio and 25% body fat, respectively. Conclusion; This study shows that it may be appropriate to reclassify some of overweight(23≤BMI<25) and Obese(25≤BMI<30) young men as normal or overweight in Republic of Korea Army considering possibility of muscle excess. If we study more subjects in the future, new and appropriate cut-off values from normal to obese could be suggested.
Untargeted metabolomics and steroid signatures in urine after finasteride treatment for a year
( Ji-hoon Lim ),( Yu Ra Lee ),( Eunju Im ),( Haksoon Kim ),( Jeongae Lee ),( Han Bin Oh ),( Ki Jung Paeng ),( Jongki Hong ),( Bong Chul Chung ),( Min-jeong Kang ),( Soon-hyo Kwon ),( Woo Young Sim ),( 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1
Sex related differences in urinary metabolic profiling of alopecia areata
( Ji-hoon Lim ),( Yu Ra Lee ),( Haksoon Kim ),( Jeongae Lee ),( Han Bin Oh ),( Jongki Hong ),( Bong Chul Chung ),( Min-jeong Kang ),( Soon-hyo Kwon ),( Woo Young Sim ),( Bark Lynn Lew ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1
Yongsik Jeong,Jaehyung Yu,Sang-Mo Koh,Chul-Ho Heo,Jeonga Lee 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.2
This study examined the spectral characteristics of minerals occurring at Weondong skarn deposit located in South Korea and assessed the effectiveness of VNIR-SWIR spectroscopic approaches in zone definition characterizing skarn deposits based on XRD, XRF, and petrographic studies. The spectroscopic analyses identified intrusive rock, garnet-clinopyroxene skarn, clinopyroxene- garnet skarn, W-ore, and host rock zones. The assessment results for VNIR-SWIR spectroscopy in skarn exploration illustrated that the spectral approaches would be very useful for attaining skarn mineral information such as calcite, chlorite, clinopyroxene, garnet, scapolite, vesuvianite, and wollastonite and clay minerals. Furthermore, the rock-forming minerals such as K-feldspar, plagioclase, quartz, fluorite, and tungsten-bearing minerals like scheelite may require supplementary mineral analysis. A combined analysis of spectrometry, XRD, XRF, UV lamp scanning, and petrographic studies reveals that the skarn mineralization of the study area related to W mineral of the study core is defined as proximal endoskarn to proximal exoskarn, which could be defined by spectroscopic approaches.
Different polyamine levels in the vertex and occipital hair of pattern hair loss patients
( Ki-hun Kim ),( Bong Chul Chung ),( Yu Ra Lee ),( Jeongae Lee ),( Jong Ki Hong ),( Bark Lynn Lew ),( Woo Young Sim ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2
Background: Pattern hair loss generally begins from the vertex or front of the head. Androgenic steroids, particularly testosterone and dihydrotestosterone are related with pattern hair loss. They existed differently in the vertex and occipital region of scalp and involved in inducing ornithine decarboxylase (ODC) expression. ODC is central enzyme in polyamine biosynthesis. The polyamine produced by ODC plays an important role in pattern hair loss by presenting at different levels along the scalp area. Objectives: This study was conducted to evaluate pathogenesis and diagnosis of patients with pattern hair loss by identifying the differences in polyamine levels according to the area of scalp. Methods: For the profiling of polyamines in patients with pattern hair loss, a liquid chromatography-mass spectrometrybased quantitative profiling method was used. We investigated the differences in polyamine levels in different regions of the hair between patients with male-pattern hair loss and those with female pattern hair loss. Results: We found almost polyamine levels were higher in vertex than occipital hair. Also we confirmed difference levels between N-acetyl polyamines and polyamines in same area of hair. Our results suggest that proliferation occurs at the vertex region rather than at the occipital region. Conclusion: High concentration of polyamine in vertex hair may relate with pattern baldness which begins at vertex.
희토류 금속이온 (Ln(III))과 Acetamide 사이의 상호작용에 대한 연구
이상원,유정아,윤창주,전유혁,최영상,Sang-Won Lee,Jeonga Yu,Chang-Ju Yoon,Yoo-Hyek Jun,Young-Sang Choi 대한화학회 1992 대한화학회지 Vol.36 No.2
아세트아미드(AA)의 CO기와 희토류 금속이온(Ln(II))을 포함하는 몇 가지 lanthanide shift reagent(LSR) 사이의 상호작용을 이해하기 위하여 AA의 $2{\nu}_{C=0}$ + amide III 조합띠를 $15^{\circ}$ ${\sim} 45^{\circ}C$에서 조사하였다. 묽은 $CCl_4$ 용액속에서 하나의 AA가 사용된 LSR에 배위되어 1 : 1 AA-LSR 복합체를 이루며, Ln(Ⅲ)이온에 대한 AA의 배위 위치는 카르보닐의 산소임을 알았다. 온도 및 농도에 따른 이 조합띠의 변화로부터 Ln(III)${\cdot}$O=C 결합에 대한 여러가지 열역학적 함수들을 구했다. Eu$(dpm)_3$, Yb$(dpm)_3$ 및 Pr$(dpm)_3$에 대한 AA의 결합의 세기를 나타내는 ${\Delta}H^{\circ}$는 각각 -39.1, -28.4 및 -25.5kJ/mol이다. 이들 값을 비교해보면 AA 분자가 배위될 때 중심금속이온의 ionic potential 효과보다는 이미 배위되어 있는 커다란 dpm 분자에 의한 입체장애효과가 더 큼을 알 수 있다. The $2{\nu}_{C=0}$ + amide III combination band spectrum of acetamide (AA) was obtained in very dilute solutions of AA+lanthanide shift reagents (LSR) in carbon tetrachloride over the range of $15^{\circ}$ to $45^{\circ}C$. It was found that only 1 : 1 AA-LSR complex is formed by the interaction between carbonyl oxygen of AA and central metal ion(Ln(Ⅲ)) in LSR. The thermodynamic parameters for Ln(III)${\cdot}$O=C bond were determined by computer analysis of concentration and temperature dependent spectra. ${\Delta}H^{\circ}$ for the coordination of AA to Eu$(dpm)_3$, Yb$(dpm)_3$, and Pr$(dpm)_3$ have been found to be -39.1, -28.4, and -25.5 kJ/mol, respectively. It has shown that this type of ion-dipole interaction is more than twice stronger compared to the dipole-dipole interaction in the amide linkage, and largely depending on the steric hindrence effect by the bulky dpm groups around central metal ion (Ln(III)) rather than the ionic potential effect of central metal ion itself.