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소아의 원발성 악성 연수막 흑색종 - 증 례 보 고 -
손영제,왕규창,김연미,신상훈,지제근,조병규,Son, Young-Je,Wang, Kyu-Chang,Kim, Youn Mee,Shin, Sang-Hoon,Chi, Je G.,Cho, Byung-Kyu 대한신경외과학회 2000 Journal of Korean neurosurgical society Vol.29 No.9
Primary malignant leptomeningeal melanoma is very rare, accounting for less than 0.1 percent of tumors in the central nervous system. Patients with primary intracranial malignant melanoma tend to be younger than metastatic intracranial melanoma, most commonly in the fourth decade of life. This tumor is extremely rare and the biologic behavior is aggressive especially in children. The authors report a case of primary malignant leptomeningeal melanoma in a twelve-year-old boy which was initially diagnosed as meningitis. On autopsy, associated extensive leptomeningeal melanosis was confirmed and believed to be the origin of the tumor. This case emphasizes the pattern of clinical presentation and the significance of leptomeningeal melanosis in primary leptomeningeal melanoma.