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Eun-Jung Joo,Janet C. King 한국식품영양과학회 1997 Preventive Nutrition and Food Science Vol.2 No.3
Thirteen healthy control, 13 pre-eclamptic, 7 diabetic(DM) and 12 gestational diabetic(GDM) pregnant women participated in a study of the interrelationships between the levels of protein, calcium, magnesium, phosphorus, zinc and copper in urine. Urinary protein, magnesium and copper levels were significantly higher(p<0.0005, p<0.0003, p<0.005 respectively) in pre-eclamptic women than those of control, DM and GDM women. Urinary zinc excretion in pre-eclamptic women(1.61㎎/g creatinine) was higher than that of DM women(0.81㎎/g creatinine); urinary zinc losses of control and GDM women were between the other two groups. The GDM women excreted significantly more phosphorus in their urine in comparison to control and preeclamptic women (p<0.002), but this was not seen in DM women. Among the DM women, urinary protein excretion was positively correlated with glycosylated hemoglobin(r=0.940) and fasting blood glucose concentration(r=0.889). Urinary zinc excretion also was correlated with glycosylated hemoglobin(r=0.853) and fasting blood glucose(r=0.956). In the GDM and pre-eclamptic women there were also significant correlations between urinary calcium and magnesium(r=0.857, r=0.749 respectively) and between urinary protein and copper(r=0.638, r=0.778 respectively).
Relationships between faecal phytate and mineral excretion depend on dietary phytate and age
Kim, Jihye,Woodhouse, Leslie R.,King, Janet C.,Welch, Ross M.,Li, Shan Ji,Paik, Hee Young,Joung, Hyojee Cambridge University Press 2009 The British journal of nutrition Vol.102 No.6
<P>We investigated the adverse effect of phytate on mineral absorption and the effect of dietary phytate and age on the relationship between faecal phytate and faecal mineral excretion. Fourteen young women (aged 19-24 years) and fourteen elderly women (64-75 years) were studied for two metabolic periods (MP). In MP1, the subjects consumed a controlled high-phytate (HP) diet for 10 d; in MP2, they were on a low-phytate (LP) diet for 10 d. In each period, diet samples and complete faecal samples for 5 d were collected to analyse phytate and mineral contents. Mineral concentrations in diet and faeces were measured by inductively coupled plasma-atomic emission spectrometry. Linear regression analysis was used to examine the associations between faecal phytate and mineral excretion. The degradation rate of dietary phytate was about 77 % for young women, which was significantly lower than that of elderly women (86 %) (<I>P</I> < 0·05). Faecal phytate excretion was positively correlated with mineral excretion (Ca, P, Fe and Zn) in both the HP and LP diet groups in young women (<I>P</I> < 0·05). The linear relationship tended to be greater during the LP diet period compared with the HP diet period in young women. However, no association was found between phytate excretion and mineral excretion in elderly women. In summary, undegraded dietary phytate (10-20 %) had a negative effect on mineral absorption in young women, and the relationship between faecal phytate and mineral excretion was affected by both dietary phytate and age.</P>