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Lee, Seungjin,Kim, Youngwoong,Wu, Ziang,Lee, Changyeon,Oh, Seung Jin,Luan, Nguyen Thanh,Lee, Junbok,Jeong, Dahyun,Zhang, Kai,Huang, Fei,Kim, Taek-Soo,Woo, Han Young,Kim, Bumjoon J. American Chemical Society 2019 ACS APPLIED MATERIALS & INTERFACES Vol.11 No.48
<P>Aqueous-processed all-polymer solar cells (aq-APSCs) are reported for the first time by developing a series of water/ethanol-soluble naphthalenediimide (NDI)-based polymer acceptors [P(NDIDEG-T), P(NDITEG-T), and P(NDITEG-T2)]. Polymer acceptors are designed by using the backbones of NDI-bithiophene and NDI-thiophene in combination with nonionic hydrophilic oligoethylene glycol (OEG) side chains that facilitate processability in water/ethanol mixtures. All three polymers exhibit sufficient solubility (20-50 mg mL<SUP>-1</SUP>) in the aqueous medium. The P(NDIDEG-T) polymer with shorter OEG side chains is the most crystalline with the highest electron mobility, enabling the fabrication of efficient aq-APSCs with the maximum power conversion efficiency (PCE) of 2.15%. Furthermore, these aq-APSCs are fabricated under ambient atmosphere by taking advantage of the eco-friendly aqueous process and, importantly, the devices exhibit outstanding air-stability without any encapsulation, as evident by maintaining more than 90% of the initial PCE in the air after 4 days. According to a double cantilever beam test, the interfacial adhesion properties between the active layer and electron/hole transporting layers were remarkably improved by incorporating the hydrophilic OEG-attached photoactive layer, which hinders the delamination of the constituent layers and prevents the increase of series resistance, ultimately leading to enhanced durability under ambient conditions. The combination of increased device stability and minimal environmental impact of these aq-APSCs demonstrates them to be worthy candidates for continued development of scalable polymer solar cells.</P> [FIG OMISSION]</BR>
Discovery of a Very Large (≈20 kpc) Galaxy at <i>z</i> = 3.72
Lee, Kyoung-Soo,Dey, Arjun,Matheson, Thomas,Shi, Ke,Hung, Chao-Ling,Xue, Rui,Inami, Hanae,Huang, Yun,Lee, Khee-Gan,Ashby, Matthew L. N.,Jannuzi, Buell,Reddy, Naveen,Hong, Sungryong,Mo, Wenli,Malavasi, American Astronomical Society 2018 The Astrophysical journal Vol.862 No.1
<P>We report the discovery and spectroscopic confirmation of a very large star-forming galaxy, G6025, at z(spec) = 3.721 +/- 0.003. In the rest frame approximate to 2100 angstrom, G6025 subtends approximate to 24 kpc in physical extent when measured from the 1.5 sigma isophote, in agreement with the parametric size measurements that yield a half-light radius of 4.9 +/- 0.5 kpc and a semimajor axis of 12.5 +/- 0.1 kpc. It is also very UV-luminous (approximate to 5L(UV,z similar to 4)*) and young (approximate to 140 +/- 60 Myr). Despite its unusual size and luminosity, the stellar population parameters and dust reddening (M-star similar to M-z similar to 4*( )and E(B - V) similar to 0.18 +/- 0.05) estimated from the integrated light are similar to those of smaller galaxies at comparable redshifts. The ground-based morphology and spectroscopy show two dominant components, both located off-center, embedded in more diffuse emission. We speculate that G6025 may be a scaled-up version of chain galaxies seen in deep HST imaging or, alternatively, a nearly equal-mass merger involving two super-L* galaxies in its early stage. It lies close to but not within a known massive protocluster at z = 3.78. We find four companions within 6 Mpc from G6025, two of which lie within 1.6 Mpc. While the limited sensitivity of the existing spectroscopy does not allow us to robustly characterize the local environment of G6025, it likely resides in a locally overdense environment. The luminosity, size, and youth of G6025 make it uniquely suited to study the early formation of massive galaxies in the universe.</P>
Ra Mi Lee,Rae Hyung Ryu,Seong Won Jeong,Soo Jin Oh,Hue Huang,Jin Soo Han,Chi Ho Lee,C. Justin Lee,Lily Yeh Jan,Sang Min Jeong 한국실험동물학회 2011 Laboratory Animal Research Vol.27 No.2
To clone the first anion channel from Xenopus laevis (X. laevis), we isolated a calcium-activated chloride channel (CLCA)-like membrane protein 6 gene (CMP6) in X. laevis. As a first step in gene isolation, an expressed sequence tags database was screened to find the partial cDNA fragment. A putative partial cDNA sequence was obtained by comparison with rat CLCAs identified in our laboratory. First stranded cDNA was synthesized by reverse transcription polymerase-chain reaction (RT-PCR) using a specific primer designed for the target cDNA. Repeating the 5’ and 3’ rapid amplification of cDNA ends, fulllength cDNA was constructed from the cDNA pool. The full-length CMP6 cDNA completed via 5’- and 3’-RACE was 2,940 bp long and had an open reading frame (ORF) of 940 amino acids. The predicted 940 polypeptides have four major transmembrane domains and showed about 50% identity with that of rat brain CLCAs in our previously published data. Semi-quantification analysis revealed that CMP6 was most abundantly expressed in small intestine, colon and liver. However, all tissues except small intestine, colon and liver had undetectable levels. This result became more credible after we did real-time PCR quantification for the target gene. In view of all CLCA studies focused on human or murine channels, this finding suggests a hypothetical protein as an ion channel, an X. laevis CLCA.
Hardening steels by the generation of transient phase using additive manufacturing
Huang, E-Wen,Lee, Soo Yeol,Jain, Jayant,Tong, Yang,An, Ke,Tsou, Nien-Ti,Lam, Tu-Ngoc,Yu, Dunji,Chae, Hobyung,Chen, Shi-Wei,Chen, Shih-Min,Chou, Hung-Sheng Elsevier 2019 Intermetallics Vol.109 No.-
<P><B>Abstract</B></P> <P>In the present work, the tensile properties of 15–5 PH steel fabricated by selective laser melting (SLM) were examined with respect to the transient austenite phase. Compared with the 8%-transient-phase sample, the 18%-transient-phase one shows higher ultimate tensile strength and relatively low yield strength, as well as hardening behavior. We conducted <I>in-situ</I> neutron-diffraction study to examine the microstructure evolution for mechanistic understanding. After applying the external load, most non-equilibrium, retained austenite in the 8%-transient-phase sample transforms before the yield strength, whereas in the 18%-transient-phase sample only 50% of the austenite transforms. Accompanying with the phase transformation, a decrease in the dislocation density and the dislocation strain energy-assisted phase transformation of the ferrite phase are found in the 8%-transient-phase sample even before yielding, which, however, is not the case in the 18%-transient-phase sample. The study demonstrates the SLM enables tuning the amount of transient-phase ratio and coherency between phases to realize a mechanical property control for additive manufactured steel.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The tensile behavior was examined for 8%- and 18%-transient-phase additive manufacturing steels using in-situ neutron diffraction. </LI> <LI> The 18%-transient-phase sample exhibited higher ultimate tensile strength and low yield strength. </LI> <LI> The 18%-transient-phase specimen with more non-equilibrium γ-phase revealed a more profound strain hardening effect. </LI> </UL> </P>
Self-assembly of Dumbbell-shaped Rod Amphiphiles Based on Dodeca-p-phenylene
Huang, Zhegang,Liu, Libin,Lee, Eun-Ji,Lee, Myong-Soo Korean Chemical Society 2008 Bulletin of the Korean Chemical Society Vol.29 No.8
Dumbbell-shaped aromatic amphiphilic molecules consisting of a dodeca-p-phenylene as a rigid segment and oligoether dendrons as a flexible chains were synthesized, characterized, and their aggregation behavior was investigated in the bulk and at the air-water interface. In contrast to the molecule 2 which shows a nematic liquid crystalline state, molecule 1 based on shorter dendritic chains was observed to self-assemble into a 3-D primitive orthorhombic supercrystal. And molecule 1 at the air-water interface was observed to reorganize from circular plates to ring structures by lateral compressions.
Rho-kinase/AMPK axis regulates hepatic lipogenesis during overnutrition
Huang, Hu,Lee, Seung-Hwan,Sousa-Lima, Inê,s,Kim, Sang Soo,Hwang, Won Min,Dagon, Yossi,Yang, Won-Mo,Cho, Sungman,Kang, Min-Cheol,Seo, Ji A.,Shibata, Munehiko,Cho, Hyunsoo,Belew, Getachew Debas,Bhi American Society for Clinical Investigation 2018 The Journal of clinical investigation Vol.128 No.12
Anti-Allergic Effect of Oroxylin A from Oroxylum indicum Using in vivo and in vitro Experiments
Lee, Ae-Yeon,Kang, Saeromi,Park, Soo-Jin,Huang, Jin,Im, Dong-Soon The Korean Society of Applied Pharmacology 2016 Biomolecules & Therapeutics(구 응용약물학회지) Vol.24 No.3
Oroxylum indicum has long been used in Asian traditional medicine to prevent and treat respiratory diseases, diabetes, diarrhea and other conditions. Oroxylin A is a flavone that is present in Oroxylum indicum and in Scutellaria baicalensis. Because the root extracts of both plants have been shown to have anti-allergic effects, the authors investigated whether oroxylin A is likely to have beneficial effects on allergic asthma using female Balb/c mice and rat RBL-2H3 mast cells. Antigen-induced degranulation was measured in vitro by measuring b-hexosaminidase activity. A murine ovalbumin-induced allergic asthma model was used to test the in vivo efficacy of oroxylin A. Sensitization and challenge of ovalbumin induced allergic asthma responses, the accumulations of eosinophils and Th2 cytokine levels in bronchoalveolar lavage fluid and lung tissues. Oroxylin A administration decreased numbers of inflammatory cells, especially eosinophils, and reduced the expression and secretion of Th2 cytokines, including IL-4 and IL-13, in lung tissues and bronchoalveolar lavage fluid. Histologic studies showed oroxylin A reduced inflammatory signs and mucin production in lungs. These findings provide evidence that oroxylin A has potential use as an anti-allergic therapeutic.
Lee, Han-Na,Huang, Jianqiang,Im, Jong-Hyuk,Kim, Seon-Hye,Noh, Jun-Hee,Cohen, Stanley N.,Kim, Eung-Soo American Society for Microbiology 2010 Applied and environmental microbiology Vol.76 No.9
<B>ABSTRACT</B><P>A <I>tetR</I> family transcriptional regulatory gene (SCO1712) was identified as a global antibiotic regulatory gene from a <I>Streptomyces</I> interspecies DNA microarray analysis. SCO1712 disruption in <I>S</I><I>treptomyces coelicolor</I> not only upregulated antibiotic biosynthesis through pathway-specific regulators when a previously identified pleiotropic downregulatory <I>wblA</I> was expressed but also further stimulated antibiotic production in a <I>wblA</I> deletion mutant, implying that SCO1712 might encode a novel antibiotic downregulator.</P>
Behavior of residual stress in plasma sprayed ZrO₂ coatings with different contents of LaPO₄
Soo Wohn Lee,Jia Zhang,Huang Chen,Tohru Sekino,Seung Ho Kim 한양대학교 세라믹연구소 2008 Journal of Ceramic Processing Research Vol.9 No.6
In this study, ZrO2-LaPO4 composite coatings were deposited by a plasma spraying technique. For nondestructive evaluation and easy practicability, the X-ray diffraction method was chosen to determine the residual stress in plasma sprayed ZrO2- LaPO4 composite coatings. The relationship between residual stress and content of LaPO4 was investigated. In this study, ZrO2-LaPO4 composite coatings were deposited by a plasma spraying technique. For nondestructive evaluation and easy practicability, the X-ray diffraction method was chosen to determine the residual stress in plasma sprayed ZrO2- LaPO4 composite coatings. The relationship between residual stress and content of LaPO4 was investigated.