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Hao Yi,Fang Zhuo,Feng Wang,Yu Li,Zhenxiong Wang 전력전자학회 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.1
For a single-phase active power filter (APF), designing a more efficient algorithm to guarantee accurate and fast harmonics extraction with a lower computing cost is still a meaningful topic. The common idea still employs a IRPT-based Park transform, which was originally designed for 3-phase applications. Therefore, an additional virtual signal generation (VSG) link is necessary when it is used in the single-phase condition. This method, with virtual signal generation and transform, is obviously not the most efficient one. Regarding this problem, this paper proposes a novel harmonics extraction algorithm to further improve efficiency. The new algorithm is based on the principle of trigonometric orthogonal functions (TOF), and its mathematical principle and physical meaning are introduced in detail. Its implementation and superiority in terms of computation efficiency are analyzed by comparing it with conventional methods. Finally, its effectiveness is well validated through detailed simulations and laboratory experiments.
Hao Yi,Fang Zhuo,Yu Li,Yanjun Zhang,Wenda Zhan 전력전자학회 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.5
Instead of extracting every selected harmonic component, the current reference of selective active power filter (APF) can be also obtained by filtering out the fundamental component from distorted load current for computation efficiency. This type of mixed current reference contains kinds of harmonic components and easily involves noises. In this condition, selective harmonic compensation must be realized by the current controller. With regard that selectivity is the most significant feature of controller, this paper presents specific comparison analysis between two types of resonant controllers: proportional-resonant (PR) controller and vector-resonant (VR) controller. The comparison analysis covers the relations, performances, and stability of both controllers. Analysis results conclude that the poorer selectivity of the PR controller could be relatively improved, but limitations from system stability make the improvement hardly realized. By contrast, the VR controller exhibits excellent selectivity and is more suitable for selective APF with mixed current reference. Experimental results from laboratory prototype validate the reasonability of analysis. And the features of each resonant controller are concluded.
SNPs in the 5’ terminal-region of IGFBP6 gene and its linkage with pig body size
Xibi Fang,Songcai Liu,Yunyun Cheng,Siming Li,Qingyan Wu,Dan Su,Chao Lu,Hao Yu,Linlin Hao 한국통합생물학회 2015 Animal cells and systems Vol.19 No.6
Insulin-like growth factor binding protein 6 (IGFBP6) is a key factor in regulating the effects of insulin-like growth factor 2 (IGF2) on the animal growth and development, but the mechanism is far from known. In this study, the 5’-terminal sequence of the IGFBP6 gene (from −920 to −1 bp) which may regulate gene expression was sequenced in the Bama mini-pigs, the Tibetan mini-pigs, the Landrace pigs, the Large White pigs and the Northeast wild boars to screen for the single nucleotide polymorphisms (SNPs) and analyze the relations with the body size traits of swine through a chi-square test analysis. The genotype frequencies of the SNPs in the 5’-terminal sequence have shown that c.-726C > T, c.-722T > C, c.-535C > A, c.- 488T > C, c.-403A > G, and c.-378T > C may be related to the dwarf traits of the Bama mini-pig and the Tibetan minipigs (P < .05). A haplotype analysis of the 5’-terminal sequence of the IGFBP6 gene in the Landrace pigs, the Large White pigs and the Northeast wild boars found the two SNPs at −403 nt and −378 nt were in linkage and formed three kinds of haplotypes; AT was the dominant haplotype and the haplotype block was not formed in the Bama mini-pigs and Tibetan mini-pigs. Above all, the SNPs and haplotypes of the 5’-terminal sequence of the IGFBP6 gene may be involved in the regulation of swine body size.
Eosinophilia in Pleural Effusions: a Speculative Negative Predictor for Malignancy
Chu, Fang-Yeh,Liou, Ching-Biau,Sun, Jen-Tang,Bei, Chia-Hao,Liou, Tse-Hsuan,Tan, N-Chi,Yu, Yun-Chieh,Chang, Chih-Chun,Yen, Tzung-Hai,Su, Ming-Jang Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.3
Background: Eosinophilic pleural effusion (EPE) is an eosinophil count more than 10% on cytology of pleural samples. Recently, it was reported that malignancy had been the most prevalent cause inducing EPE. Therefore, we conducted an analysis on the prevalence and etiology of EPE and investigated the relationship between EPE and malignancy. Materials and Methods: Data for pleural cell differential count from patients receiving thoracentesis during the period from January 2008 to December 2013 were compared with clinical data and established diagnosis of patients obtained via electronic chart review. Results: A total of 6,801 requests of pleural cytology from 3,942 patients with pleural effusion who had received thoracentesis were available at Far Eastern Memorial Hospital from 2008 to 2013, and of these subjects, 115 (2.9%) were found to have EPE. The most frequent cause of EPE was malignancy (33.0%, n=38), followed by parapneumonic effusions (27.8%, n=32), tuberculosis pleuritis (13.9%, n=16), transudate effusions (12.2%, n=14) and the presence of blood or air in pleural space (10.4%, n=12). Additionally, an inverse relationship of eosinophilia in pleural fluid was identified in patients with malignancy and EPE. The cut-off eosinophil count in pleural fluid was 15% for the most accurate discrimination between malignancy and benign disorders in patients with EPE. At the cut-off level, the sensitivity and specificity were 65.8% and 67.5%, respectively. Conclusions: Pleural fluid eosinophilia was a speculative negative predictor for malignancy, despite the fact that cancers, including lung cancers and metastatic cancers to lung, were the most leading cause of pleural fluid eosinophilia. An inverse correlation was observed between the pleural eosinophil percentage and the likelihood of malignancy in patients with EPE.
Yi, Hao,Zhuo, Fang,Li, Yu,Zhang, Yanjun,Zhan, Wenda The Korean Institute of Power Electronics 2013 JOURNAL OF POWER ELECTRONICS Vol.13 No.5
Instead of extracting every selected harmonic component, the current reference of selective active power filter (APF) can be also obtained by filtering out the fundamental component from distorted load current for computation efficiency. This type of mixed current reference contains kinds of harmonic components and easily involves noises. In this condition, selective harmonic compensation must be realized by the current controller. With regard that selectivity is the most significant feature of controller, this paper presents specific comparison analysis between two types of resonant controllers: proportional-resonant (PR) controller and vector-resonant (VR) controller. The comparison analysis covers the relations, performances, and stability of both controllers. Analysis results conclude that the poorer selectivity of the PR controller could be relatively improved, but limitations from system stability make the improvement hardly realized. By contrast, the VR controller exhibits excellent selectivity and is more suitable for selective APF with mixed current reference. Experimental results from laboratory prototype validate the reasonability of analysis. And the features of each resonant controller are concluded.
Chih-Hao Chiu,Yun-Wen Tong,Jen-Fang Yu,Kin Fong Lei,Alvin Chao-Yu Chen 한국바이오칩학회 2020 BioChip Journal Vol.14 No.4
Periosteal cells are the major cell sources of skeletal progenitors for fracture callus. In order to promote bone repair and cartilage formation, besides the application of exogenous growth factors, physical stimulation is an alternative approach to guide cell differentiation. Investigation of appropriate conditions is essential for forming bone and cartilage. In this work, a membrane-type micro-system was developed to provide cell culture environment and cell stretching stimulation during culture course. Circular and oval culture wells were designed to respectively generate uniform and non-uniform 2-axial tensile strain for stretching primary rabbit periosteal cells. Cell orientation and differentiation were studied after cycling stretching for 2 days. The cells aligned to the stretching axis with high tensile strain in the oval culture wells; while the cells expressed random orientation in the circular culture wells. Different responses were significantly shown when the cells were respectively stimulated by uniform and non-uniform 2-axial tensile strains. On the other hand, osteogenic differentiation was shown when the cells were under either uniform or non-uniform 2-axial tensile strain. However, only non-uniform 2-axial tensile strain could induce mature osteoblasts. In addition, the result revealed chondrocytes could be differentiated only under a large and nearly single dimensional tensile strain. In summary, differentiation of the periosteal cells is highly influenced by 2-dimensional distribution of the tensile strain. This work provides some in-sights of the control of axial tensile strain for periosteal cell differentiation.
Yi, Hao,Zhuo, Fang,Wang, Feng,Li, Yu,Wang, Zhenxiong The Korean Institute of Power Electronics 2017 JOURNAL OF POWER ELECTRONICS Vol.17 No.1
For a single-phase active power filter (APF), designing a more efficient algorithm to guarantee accurate and fast harmonics extraction with a lower computing cost is still a meaningful topic. The common idea still employs a IRPT-based Park transform, which was originally designed for 3-phase applications. Therefore, an additional virtual signal generation (VSG) link is necessary when it is used in the single-phase condition. This method, with virtual signal generation and transform, is obviously not the most efficient one. Regarding this problem, this paper proposes a novel harmonics extraction algorithm to further improve efficiency. The new algorithm is based on the principle of trigonometric orthogonal functions (TOF), and its mathematical principle and physical meaning are introduced in detail. Its implementation and superiority in terms of computation efficiency are analyzed by comparing it with conventional methods. Finally, its effectiveness is well validated through detailed simulations and laboratory experiments.