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RISS 인기검색어
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- 저자 : Haiyang Xie (검색결과 5 건)
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Thermodynamic analysis of a novel adiabatic compressed air energy storage system with water cycle
Zhen Xu,Haiyang Yang,Yingchun Xie,Jinchi Zhu,Chaoqun Liu 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.6
A novel water cycle compressed air energy storage system (WC-CAES) is proposed to improve the energy storage density (ESD) and round trip efficiency (RTE) of A-CAES. The new system decreases electricity consumption by recovering and reusing the hydraulic pressure of water. The thermodynamic characteristics of WC-CAES are evaluated by energy and advanced exergy analysis method. When the air storage pressure of WC-CAES is equal to the minimum storage pressure of A-CAES (4.2 MPa), the ESD and generalized storage density increase by 5.85 % and 32.41 %, respectively. When the air storage pressure increases to the same level as A-CAES (7.2 MPa), ESD and generalized storage density increase by 112 % and 162 %, respectively. In addition, the RTE increases by 1.6 % when the air storage pressure is 4.2 MPa. WC-CAES is therefore verified to be an effective way to improve the performance of conventional A-CAES.
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Xuechen Rao,Lanxiang Liu,Haiyang Wang,Ying Yu,Wenxia Li,Tingjia Chai,Wei Zhou,Ping Ji,Jin-Lin Song,Hong Wei,Peng Xie 한국뇌신경과학회 2021 Experimental Neurobiology Vol.30 No.1
An increasing number of studies have recently indicated the important effects of gut microbes on various functions of the central nervous system. However, the underlying mechanisms by which gut microbiota regulate brain functions and behavioral phenotypes remain largely unknown. We therefore used isobaric tags for relative and absolute quantitation (iTRAQ)-based quantitative proteomic analysis to obtain proteomic profiles of the hippocampus in germ-free (GF), colonized GF, and specific pathogen-free (SPF) mice. We then integrated the resulting proteomic data with previously reported mRNA microarray data, to further explore the effects of gut microbes on host brain functions. We identified that 61 proteins were upregulated and 242 proteins were downregulated in GF mice compared with SPF mice. Of these, 124 proteins were significantly restored following gut microbiota colonization. Bioinformatic analysis of these significant proteins indicated that the glucocorticoid receptor signaling pathway and inflammation-related pathways were the most enriched disrupted pathways. This study provides new insights into the pathological mechanisms of gut microbiota-regulated diseases.
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Xiong Zhiyong,Wen Zhuoqi,Cui Zhongjie,Mei Shiliang,He Haiyang,Duan Zhongtao,Zhang Wanlu,Xie Fengxian,Guo Ruiqian 한국물리학회 2023 Current Applied Physics Vol.45 No.-
Hysteresis effects in self-luminous devices like organic light-emitting diodes (OLEDs) and perovskite light-emitting diodes (PeLEDs) have been discovered recently, besides emerging in thin film transistors (TFTs). However, the influences of lateral leakage caused by next-door devices on hysteresis effects in flexible OLEDs array have rarely been demonstrated. To mitigate the impact of lateral leakage and figure out the detailed relationship with hysteresis effects, a series of experiments for OLEDs array involving p-doping in holes transport layer (HTL) were employed. It is found that the lateral leakage and hysteresis effects have a trade-off exhibition, which means stronger lateral leakage has induced weaker hysteresis effects. In order to get rid of the role of lateral leakage, the experiments with mono blue devices were also performed to substantiate the intrinsic hysteresis effects existence. The research opens the possibility of considering more internal relationships between different performances on self-luminous arrays for their actual application.
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Qiang Wei,Xiao Xu,Chao Wang,Runzhou Zhuang,Li Zhuang,Lin Zhou,Haiyang Xie,Jian Wu,Min Zhang,Yan Shen,Weilin Wang,Shusen Zheng 거트앤리버 소화기연관학회협의회 2016 Gut and Liver Vol.10 No.4
Background/Aims: We aimed to evaluate the efficacy and safety of an immunosuppressive regimen without steroids after liver transplantation (LT) for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). Methods: Sixty-six HCC patients who underwent an immunosuppressive regimen without steroids after LT were enrolled in the steroid-free group. The preoperative characteristics and postoperative outcomes of these patients were compared with those of 132 HCC recipients who were placed on an immunosuppressive regimen using steroids (steroid group). The incidence of acute rejection, HBV recurrence, infection, and new-onset diabetes mellitus and the overall and tumor-free survival rates were compared between the two groups. Results: Differences were not observed in the 1-year (83.3% vs 97.0%, p=0.067), 3-year (65.4% vs 75.8%, p=0.067) or 5-year (56.3% vs 70.7%, p=0.067) patient survival rates or in the 1-year (62.1% vs 72.7%, p=0.067), 3-year (49.8% vs 63.6%, p=0.067) or 5-year (48.6% vs 63.6%, p=0.067) tumor-free survival rates between the two groups, respectively. In the steroid-free group, the patients who fulfilled the Milan criteria had higher overall and tumor-free survival rates than those in the steroid group (p<0.001). The prevalence of HBV recurrence (3.0% vs 13.6%, p=0.02) was significantly lower in the steroid-free group compared with the steroid group. Conclusions: After LT, an immunosuppressive regimen without steroids could be a safe and feasible treatment for HBVrelated HCC patients, thus resulting in the reduction of HBV recurrence. Based on the observed survival rates, patients who fulfill the Milan criteria may derive benefits from steroidfree immunosuppression.
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( Jun Ding ),( Kangdi Xu ),( Jie Zhang ),( Bingyi Lin ),( Yubo Wang ),( Shengyong Yin ),( Haiyang Xie ),( Lin Zhou ),( Shusen Zheng ) 생화학분자생물학회 2018 BMB Reports Vol.51 No.12
C-X-C motif chemokine ligand 2 (CXCL2) is a small secreted protein that exhibits a structure similar to the proangiogenic subgroup of the CXC chemokine family. Recently, accumulating evidence suggests that chemokines play a pivotal role in cancer progression and carcinogenesis. We examined the expression levels of 7 types of ELR+ CXCLs messenger RNA (mRNA) in 264 clinical samples. We found that CXCL2 expression was stably down-regulated in 94% of hepatocellular carcinoma (HCC) specimens compared with paired adjacent normal liver tissues and some HCC cell lines. Moreover, CXCL2 overexpression profoundly attenuated HCC cell proliferation and growth and induced apoptosis in vitro. In animal studies, we found that overexpressing CXCL2 by lentivirus also apparently inhibited the size and weight of subcutaneous tumours in nude mice. Furthermore, we demonstrated that CXCL2 induced HCC cell apoptosis via both nuclear and mitochondrial apoptosis pathways. Our results indicate that CXCL2 negatively regulates the cell cycle in HCC cells via the ERK1/2 signalling pathway. These results provide new insights into HCC and may ultimately lead to the discovery of innovative therapeutic approaches of HCC. [BMB Reports 2018; 51(12): 630-635]
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