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RISS 인기검색어
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- 저자 : H.E.A. El-Sayed (검색결과 5 건)
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Kholif, A.E.,Khattab, H.M.,El-Shewy, A.A.,Salem, A.Z.M.,Kholif, A.M.,El-Sayed, M.M.,Gado, H.M.,Mariezcurrena, M.D. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.3
The study evaluated replacement of Egyptian berseem clover (BC, Trifolium alexandrinum) with spent rice straw (SRS) of Pleurotus ostreatus basidiomycete in diets of lactating Baladi goats. Nine lactating homo-parity Baladi goats (average BW $23.8{\pm}0.4$ kg) at 7 d postpartum were used in a triplicate $3{\times}3$ Latin square design with 30 d experimental periods. Goats were fed a basal diet containing 0 (Control), 0.25 (SRS25) and 0.45 (SRS45) (w/w, DM basis) of SRS. The Control diet was berseem clover and concentrate mixture (1:1 DM basis). The SRS45 had lowered total feed intake and forages intake compared to Control. The SRS25 and SRS45 rations had the highest digestibilities of DM (p = 0.0241) and hemicellulose (p = 0.0021) compared to Control which had higher (p<0.01) digestibilities of OM (p = 0.0002) and CP (p = 0.0005) than SRS25 and SRS45. Ruminal pH and microbial protein synthesis were higher (p<0.0001) for SRS25 and SRS45 than Control, which also had the highest (p<0.0001) concentration of TVFA, total proteins, non-protein N, and ammonia-N. All values of serum constituents were within normal ranges. The Control ration had higher serum globulin (p = 0.0148), creatinine (p = 0.0150), glucose (p = 0.0002) and cholesterol (p = 0.0016). Both Control and SRS25 groups had the highest (p<0.05) milk (p = 0.0330) and energy corrected milk (p = 0.0290) yields. Fat content was higher (p = 0.0373) with SRS45 and SRS25 groups compared with Control. Replacement of BC with SRS in goat rations increased milk levels of conjugated linoleic acid and unsaturated fatty acids compared with Control. It was concluded that replacing 50% of Egyptian berseem clover with SRS in goat rations improved their productive performance without marked effects on metabolic indicators health.
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Emad H. M. Hassanein,Ahmed M. Sayed,Omnia A. M. Abd El-Ghafar,Zainab M. M. Omar,Eman K. Rashwan,Zuhair M. Mohammedsaleh,So Young Kyung,Jae Hyeon Park,Hyung Sik Kim,Fares E. M. Ali 대한약학회 2023 Archives of Pharmacal Research Vol.46 No.4
The present study was designed to evaluate the potential renoprotective impacts of apocynin (APC) against nephrotoxicity induced by methotrexate (MTX) administration. To fulfill this aim, rats were allocated into four groups: control; APC (100 mg/kg/day; orally); MTX (20 mg/kg; single intraperitoneal dose at the end of the 5th day of the experiment); and APC +MTX (APC was given orally for 5 days before and 5 days after induction of renal toxicity by MTX). On the 11th day, samples were collected to estimate kidney function biomarkers, oxidative stress, pro-inflammatory cytokines, and other molecular targets. Compared to the MTX control group, treatment with APC significantly decreased urea, creatinine, and KIM-1 levels and improved kidney histological alterations. Furthermore, APC restored oxidant/antioxidant balance, as evidenced by a remarkable alleviation of MDA, GSH, SOD, and MPO levels. Additionally, the iNOS, NO, p-NF-κB-p65, Ace-NF-κB-p65, TLR4, p-p38-MAPK, p-JAK1, and p-STAT-3 expressions were reduced, while the IκBα, PPAR-γ, SIRT1, and FOXO3 expressions were significantly increased. In NRK-52E cells, MTX-induced cytotoxicity was protected by APC in a concentration-dependent manner. In addition, increased expression of p-STAT-3 and p-JAK1/2 levels were reduced in MTX-treated NRK-52E cells by APC. The in vitro experiments revealed that APC-protected MTX-mediated renal tubular epithelial cells were damaged by inhibiting the JAK/STAT3 pathway. Besides, our in vivo and in vitro results were confirmed by predicting computational pharmacology results using molecular docking and network pharmacology analysis. In conclusion, our findings proved that APC could be a good candidate for MTX-induced renal damage due to its strong antioxidative and anti-inflammatory bioactivities.
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Taha A. El-Sayed,Kareem S. Abdallah,Hossam E. Ahmed,Tamer H. El-Afandy 한국콘크리트학회 2023 International Journal of Concrete Structures and M Vol.17 No.6
The axial compressive behavior of Ultra-High Strength Concrete (UHPC) columns reinforced with basalt bars was investigated in this work. Only a few research projects have used basalt Reinforced Concrete Columns. Under axial stress, 12 columns of 150 × 150 mm in cross section and 1200 mm in height manufactured of M120 grade UHPC, incorporating glass powder lime powder, were tested. The primary characteristics investigated in this study were axial load capacity, axial deformation, failure pattern, ductility, and stiffness. The findings of the experimental tests revealed that the ultimate loads and behavior of UHPCC reinforced with BFRP were superior to concrete columns strengthened with steel reinforcement. When compared to steel RC columns, basalt RC columns carry about 90% of the axial load. Moreover, the BFRP bar tensile strength was 2.5 greater than reinforcing steel yield strength and 1.79 times larger than that of bar. The Ansys software-based analytical analysis assisted in predicting the eventual carrying capacity of UHPC columns. The agreement among the experimental and NLFE ultimate load is around 92.2%, with a standard deviation of 0.005 and a coefficient of variation of 0.00002. The nonlinear BFRP–UHPC columns’ structural performance was adequately predicted by the finite element analysis. In addition, equations are employed to forecast the strength of confined concrete. Equation 4 merely produced improved forecasts, it aids in comparing the outcomes of analytical and experimental tests. Results of this study indicated that the UHPC-columns reinforced with BFRP bars offer potential economic and environmental advantages as compared to traditional RC columns.
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M.M. El-Nahass,H.S. Metwally,H.E.A. El-Sayed,A.M. Hassanien 한국물리학회 2014 Current Applied Physics Vol.14 No.2
The JeV characteristics of the Au/5,10,15, 20-tetraphenyl-21H, 23H-porphine iron (III) chloride (FeTPPCl)/ ITO device exhibits rectifying behavior in the dark which can be explained due to the formation of Schottky barrier at ITO/FeTPPCl junction and the typical junction parameters were estimated in temperatures from 302 to 368 K. The temperature dependence of DC electrical conductivity showed that FeTPPCl films behave as semiconducting materials. These results indicate that the DC electrical conduction is through an activated process having three conduction mechanisms in the investigated range of temperatures. A variable range hopping model, a polaron model and band to band transitions have been used to explain the conduction mechanisms for FeTPPCl films.
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Al-Khamees, Hamad A.,Kandil, Hesham A.,El-Tahir, Kamal E.H.,Bayomi, Said M. The Pharmaceutical Society of Korea 1993 Archives of Pharmacal Research Vol.16 No.3
Two series of substituted sulforrythiazolidin-4-ones and sulforrylthiazolines have been synthesized and examined for their antidiabetic and biological aticity.
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