Asymptomatic carriage of Clostridioides difficile in pet shop puppies

Yuya Kimura(Yuya Kimura ),Satoshi Kameshima(Satoshi Kameshima ),Naoyuki Itoh(Naoyuki Itoh ) 한국예방수의학회 2023 예방수의학회지 Vol.47 No.2

Crowded pet shops can become infected with various pathogens. Although dog carriers of Clostridioides difficile tend to be asymptomatic, the toxigenic strains sometimes cause gastrointestinal symptoms in humans. The present study was conducted to determine the infection rate of C. difficile in pet shops. The feces of 137 dogs younger than one year of age, collected from four pet shops, were assessed by culture and PCR. Carriage rates of C. difficile in dogs aged ≤90, 91-180, and ≥181 day-old were 12.2% (10/82, 95% confidence interval: 6.0-21.3%), 0.0% (0/42, 95% confidence interval: 0.0-8.4%), and 7.7% (1/13, 95% confidence interval: 0.2-36.0%), respectively. Five C. difficile isolates carried genes encoding toxins A and B, while the remaining isolates contained only toxin B. However, none of the C. difficile carriers had diarrhea. These results highlight the necessity of promoting adequate hygiene precautions in pet shops to prevent infection by C. difficile.

Determination of the Anisotropic Rotational Diffusion Constant of Microcrystals Dispersed in Liquid Medium

Kimura, Fumiko,Horii, Shigeru,Arimoto, Itsuki,Doi, Toshiya,Yoshimura, Masato,Wada, Masahisa,Kimura, Tsunehisa American Chemical Society 2018 The Journal of physical chemistry A Vol.122 No.46

<P>Microcrystals of ErBa<SUB>2</SUB>Cu<SUB>4</SUB>O<SUB>8</SUB> suspended in a liquid medium were triaxially aligned by a frequency-modulated magnetic field and allowed a free rotational relaxation after the magnetic field was turned off. In situ X-ray diffraction measurements of the suspension were performed during relaxation, and the temporal change of the orientation fluctuation was monitored via broadening of the diffraction spots. The rotational diffusion constants were determined using the plot of the orientation fluctuation versus the elapsed time of rotational relaxation. The diffusion constants thus determined were in close agreement with those evaluated by the Stokes law but showed slight anisotropy, indicating that the microcrystals studied had shape anisotropy. The present method can provide a useful means for experimentally determining rotational diffusion constants of microcrystals suspended in viscous media. This paper shows that, due to the combination of the initial triaxial alignment and the subsequent monitoring of the relaxation process by means of X-ray diffraction, the diffusion constants along arbitrary crystallographic axes are determined separately.</P> [FIG OMISSION]</BR>

한방엑스제제의 제조에 관한 기술의 진보

Takayoshi Kimura 한국약제학회 1988 Journal of Pharmaceutical Investigation Vol.18 No.4

폼 / 쿠이치 키무라 아키텍츠

폼 / 쿠이치 키무라 아키텍츠(FORM / Kouichi Kimura Architec),요시히로 아사다(사진),케이 나카지마(사진),타쿠미 오타(사진) 현대건축사 2016 월간 CONCEPT Vol.- No.209

異文化コミュニケ?ション入門書のディスコ?ス : 「自己開示」に?する記述に着目して

Kimura Arinobu(木村有伸) 韓國外國語大學校 外國學綜合硏究센터 日本硏究所 2015 日本硏究 Vol.0 No.64

본 원고에서는 문화 비교 접근인 이문화 커뮤니케이션(ICC)론에서 문화나 문화의 차이에 대해 이야기 하는 점을 문제로 들기 위해 ICC입문서 중 「자기표출」에 관한 기술을 분석했다. 그 결과, 미국과 일본의 자기표출 정도에 관한 조사결과가 ICC입문서에서도 다뤄지고 있는 점, 그리고 그 자기표출의 차이를 설명 할 때에 문화 비교 접근이 주류였던 1990년대 이전뿐만이 아니라, 비교적 최근의 입문서에서도 문화차이를 강조하는 이항대립개념이나 인과명제를 게시하는 방법이 사용된 점을 확인했다. 이렇게 인과명제가 많이 쓰이는 것은 문화간의 차이를 강조할 뿐만이 아니라, 문화적인 고정관념을 만들어내는 것이다. 본 원고에서는 문화 차이에 대한 이러한 언설이 ICC입문서에서 반복적으로 사용되어 온 점은 학습자가 이문화를 이해하는 것을 방해해왔다고 비판했다. Although the validity of academic discourse that emphasizes cultural differences has been challenged, it has been shown that in academic arguments, this belief remains strong. Therefore, this study examines several introductions of intercultural communication that adopt a cultural comparison approach and demonstrate the continuity of such a belief. This study also analyzes the discourse regarding "self-disclosure" in these introductions. First, it demonstrates that 19 out of 34 books focus on the concept of self-disclosure. Second, it shows that the authors of these introductions often use dichotomy between two cultures and causal propositions in order to emphasize the difference of self-disclosure between Japanese and American individuals. However, since various approaches, such as these introductions, include a methodological problem (i.e., a lack of comparison), it is remarkable that hypothetical descriptions based on such scarce supporting evidence are still quoted as academic propositions.

The Possibility and Prospects of Northeast Asian Integration : From the Japanese Perspective

Kimura, Fukunari 한국비교경제학회 2002 비교경제연구 Vol.9 No.2

Imagine the world in the year of 2015. Europe would expand the geographical coverage of deep integration. North America and Latin America would form FTAA(Free Trade Area of Americas), and even TAFTA(Trans-Atlantic Free Trade Area) could be concluded. Then what would happen in East Asia? The move of Korea and Japan in the coming few years will be very crucial for the future of economic integration in East Asia. Korea and Japan can establish a more equal-footing relationship than ever and have responsibility in maintaining economic dynamism of the region. The author hopes that the NAIS movement becomes a big step forward in the direction of regional integration. We cannot envisage, however, that a deep integration including all the economies in Northeast Asia will be immediately realized. We mut develop tighter communications with each other and go forward step by step. In this regard, it seems natural to initiate regional integration with the Korea-Japan FTA.

Comments on heterotic flux compactifications

Kimura, Tetsuji,Yi, Piljin Institute of Physics Pub 2006 The journal of high energy physics Vol.2006 No.7

In heterotic flux compactification with supersymmetry, three different connections with torsion appear naturally, all in the form ω+<I>aH</I>. Supersymmetry condition carries <I>a</I> = −1, the Dirac operator has <I>a</I> = −1/3, and higher order term in the effective action involves <I>a</I> = 1. With a view toward the gauge sector, we explore the geometry with such torsions. After reviewing the supersymmetry constraints and finding a relation between the scalar curvature and the flux, we derive the squared form of the zero mode equations for gauge fermions. With d<I>H</I> = 0, the operator has a positive potential term, and the mass of the unbroken gauge sector appears formally positive definite. However, this apparent contradiction is avoided by a no-go theorem that the compactification with <I>H</I>&neq;0 and d<I>H</I> = 0 is necessarily singular, and the formal positivity is invalid. With d<I>H</I>&neq;0, smooth compactification becomes possible. We show that, at least near smooth supersymmetric solution, the size of <I>H</I><SUP>2</SUP> should be comparable to that of d<I>H</I> and the consistent truncation of the action has to keep α′<I>R</I><SUP>2</SUP> term. A warp factor equation of motion is rewritten with α′<I>R</I><SUP>2</SUP> contribution included precisely, and some limits are considered.

환기시스템에 의한 Sick House 대책

Kimura, Hiroshi 대한설비공학회 2003 설비저널 Vol.32 No.9

"환기"는 생활용품 등으로부터의 오염물질 및 불특정 물질의 농도 저감이 가능하기 때문에 Sick House 대책으로서의 중요한 대책기술이다. 본 고에서는 집합주택을 대상으로 한 중앙공조 환기방식 및 배기 중앙 환기방식의 사례를 보여주고, 시스템의 구성기술과 오염물질의 농도 저감효과에 대해서 기술한다. 또한, 대표적인 오염물질인 포름알데히드의 건자재로 부터의 발산량은 온습도, 환기량 및 건자재의 표면적 비율 등의 영향인자에 따라 변화하므로, 필요 환기량은 이들의 영향요인을 고려하여야 한다는 것을 기술한다.

COMPUTATIONS OF TURBULENCE STRUCTURES IN FREE-SURFACE MIXING LAYERS UNDER DIFFERENT DEPTHS

KIMURA ICHIRO,HOSODA TAKASHI 한국수자원학회 2005 한국수자원학회 학술대회 Vol.2005 No.1

Development of a Human Mammary Epithelial Cell Culture Model for Evaluation of Drug Transfer into Milk

Kimura Soichiro,Morimoto Keiko,Okamoto Hiroshi,Ueda Hideo,Kobayashi Daisuke,Kobayashi Jun,Morimoto Yasunori The Pharmaceutical Society of Korea 2006 Archives of Pharmacal Research Vol.29 No.5

In the present study, a human mammary epithelial cell (HMEC) culture model was developed to evaluate the potential involvement of carrier-mediated transport systems in drug transfer into milk. Trypsin-resistant HMECs were seeded on $Matrigel^{circledR}-coated$ filters to develop monolayers of functionally differentiated HMEC. Expression of the specific function of HMEC monolayers was dependent of the number of trypsin treatments. Among the monolayers with different numbers of treatment (treated 1 to 3 times), the monolayer treated 3 times (3-t-HMEC monolayer) showed the highest maximal transepithelial resistance and expression of $\beta-casein$ mRNA as an index of differentiation. Transport of tetraethylammonium (TEA) across the 3-t-HMEC monolayer in the basolateral-to-apical direction was significantly higher than that in the apical-to-basolateral direction (p<0.05), whereas such directionality was not observed for p-aminohippurate, suggesting the existence of organic cation transporters, but not organic anion transporters. In fact, expression of mRNAs of human organic cation transporter (OCT) 1 and 3 were detected in the 3-t-HMEC monolayer. These results indicate that the 3-t-HMEC monolayer is potentially useful for the evaluation of carrier-mediated secretion of drugs including organic cations into human milk.