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- 검색키워드
- 저자 : Gyanendra Kumar Singh (검색결과 2 건)
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Gyanendra Kumar Singh,Vinod Yadava,Raghuvir Kumar 한국정밀공학회 2010 International Journal of Precision Engineering and Vol.11 No.4
Electro-discharge machining (EDM) characteristics of tungsten carbide-cobalt composite are accompanied by a number of problems such as the presence of resolidified layer, large tool wear rate and thermal cracks. Use of combination of conventional grinding and EDM (a new hybrid feature) has potential to overcome these problems. This article presents the face grinding of tungsten carbide-cobalt composite (WC-Co) with electrical spark discharge incorporated within face of wheel and flat surface of cylindrical workpiece. A face grinding setup for electro- discharge diamond grinding (EDDG) process is developed. The effect of input parameters such as wheel speed, current, pulse on-time and duty factor on output parameters such as material removal rate (MRR), wheel wear rate (WWR) and average surface roughness (ASR), are investigated. The present study shows that MRR increases with increase in current and wheel speed while it decreases with increase in pulse on-time for higher pulse on-time (above 100 μs). The most significant factor has been found as wheel speed affecting the robustness of electro- discharge diamond face grinding (EDDFG) process.
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Kumar Arun,Kumar Vikas,Akhouri Vivek,Kumar Ranjit,Ali Mohammad,Rashmi Tuhin,Chand Gyanendra Bahadur,Singh Sushil Kumar,Ghosh Ashok Kumar 한국독성학회 2022 Toxicological Research Vol.38 No.4
Arsenic poisoning in ground water is one of the most sensitive environmental pollutant causing serious pollution all over the world. Chronic arsenic exposure through drinking water to humans leads to major public health related issues. There have been very meagre studies which reported that, the plant constituents proved to exhibit protective effect from arsenicosis. Therefore, the present study aims to evaluate the protective efficacy of Coriandrum sativum seeds extract against sodium arsenite induced toxicity in Swiss albino mice. In the present study twenty-four male healthy Swiss albino mice (30 ± 5 g) were divided into four groups (n = 6), where the control group received normal diet and water; group II and group III treated with sodium arsenite (2 mg per kg body weight per day) for 2 and 4 weeks respectively. The group IV mice were administered with C.sativum seeds extract at the dose of 150 mg per kg body weight per day for 4 weeks upon sodium arsenite pretreated (2 mg/kg body weight for 4 weeks per day) mice. After the complete dose duration, all the treatment group animals were sacrificed same day for haematological, biochemical and histopathological study. In the arsenic treated mice, there were significant (p < 0.0001) changes in the serum levels of ALT, AST, ALP, urea, uric acid and creatinine as well as in the haematological parameters. In contrast, after the administration with C.sativum seeds extract upon arsenic pretreated mice, there was significant (p < 0.0001) improvement observed in the hepatic and renal biomarker parameters as well as haematological variables. In the arsenic intoxicated mice, after administration with C.sativum seeds extract there was significant (p < 0.0001) reduction in the arsenic concentration in blood, liver and kidney tissues as well as in the serum LPO levels. Furthermore, the histopathological study showed that, C.sativum seeds extract administrated group of mice significantly restored the liver and kidney at cellular level against arsenic induced toxicity. The entire study concludes that C.sativum seeds extract possesses the ameliorative effect against arsenic induced liver and kidney intoxication.
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