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        Waiguan Stimulation May Kindle Anticorrelated Brain Networks: Functional Magnetic Resonance Imaging Data Revisited

        Gustav Wik,Yong Huang,Tongjun Zeng,Shanshan Qu,Yu Zheng,Jiping Zhang,Xinsheng Lai,Chunzhi Tang,Baoci Shan 사단법인약침학회 2016 Journal of Acupuncture & Meridian Studies Vol.9 No.1

        Subtraction of functional magnetic resonance imaging activity data results in a loss of information regarding possible general patterns of brain activation under experimental conditions. We, hence, reanalyzed previous Waiguan acupuncture data to qualitatively elucidate patterns of cerebral correlations to acupuncture and placebo conditions. Healthy individuals (n=24) were randomly allocated to true and sham Waiguan acupuncture and to true and sham needling of a nonacupuncture point (nonacupoint), and functional magnetic resonance imaging scans were performed during stimulation. Statistical parametric mapping group comparisons revealed clearly different patterns of activation between Waiguan stimulation and the corresponding stimulation of a nonacupoint. The former condition produced less neocortical activation than the nonacupoint stimulation. Cerebellar activation was typically seen only during true Waiguan acupuncture. The reduced neocortical activity during both true and sham Waiguan acupuncture may indicate that this point activates anticorrelated networks, with possible intrinsic healing properties. Cerebellar activation during true Waiguan acupuncture implies the region's influence on healing networks.

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        A Naturalistic Study of the Effect of Acupuncture on Heart-Rate Variability

        Ole Bernt Fasmer,Yong Huang,Hanbo Liao,Jan Øystein Berle,Junxian Wu,Ketil Joachim Oedegaard,Gustav Wik,Zhangjin Zhang 사단법인약침학회 2012 Journal of Acupuncture & Meridian Studies Vol.5 No.1

        Objectives: To study the effect of acupuncture on heart rate variability (HRV) by using linear and non-linear methods of analysis. Methods: 40 patients were recruited consecutively, including patients with insomnia, stomachache,diarrhea, dizziness, cervical syndrome, lower back pain, gonarthritis, peripheral facial paralysis, post-traumatic organic brain syndrome and urinary retention. Different acupoint prescriptions were used, according to the textbook for 5-years’ education on traditional Chinese medicine specialty, which is used in Chinese Universities. HRV was recorded before,during, and after acupuncture. Results: Acupuncture substantially reduced variability, causing a 41% reduction in the standard deviation. Using a Fourier analysis, the variances both in the low frequency (LF) and the high frequency (HF) ranges were markedly reduced, but the LF/HF ratio (an indication of sympathovagal balance) was not altered. The HR was unchanged. The sample entropy, which is a measure of the complexity of time series, was significantly increased (þ35%). Conclusions: Acupuncture produced a pattern of changes different from that seen in pathological conditions, where increased variability and reduced complexity is expected.

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