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Diphoton signal of the light Higgs boson in natural NMSSM
Cao, Junjie,Guo, Xiaofei,He, Yangle,Wu, Peiwen,Zhang, Yang American Physical Society 2017 Physical review. D Vol.95 No.11
<P>The natural Next-to-Minimal Supersymmetric Standard Model (nNMSSM) is featured by predicting one CP-even Higgs boson satisfying m(h1) less than or similar to 120 GeV and Higgsinos lighter than about 300 GeV, and consequently, the cross section for dark matter (DM)-nucleon scattering in this scenario is usually quite large. We study the diphoton signal of the light Higgs boson in nNMSSM by considering the tight constraints from the latest LUX and PandaX-II experiments, and we conclude that the optimal value of the signal rate at 8 TeV LHC is greatly reduced in comparison with earlier predictions. For example, previous studies indicated that the rate may exceed 120 fb for m(h1) similar or equal to 80 GeV, while it is at most 25 fb if the lightest neutralino in the scenario is fully responsible for the measured DM relic density. We also investigate the case of m(h1) similar or equal to 98 GeV, which is hinted by the excesses of the large electron proton collider analysis on Z (b) over bar b signal and the compact muon solenoid analysis on the diphoton signal. We conclude that nNMSSM can simultaneously explain the excesses at the 1 sigma level without violating any known constraints.</P>
Zhang Zhaoqi,Guo Peiwen,Liang Liang,Jila Shiju,Ru Xufang,Zhang Qiang,Chen Jingyu,Chen Zhi,Feng Hua,Chen Yujie 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Hydrocephalus is a severe complication that can result from intracerebral hemorrhage, especially if this hemorrhage extends into the ventricles. Our previous study indicated that the NLRP3 inflammasome mediates cerebrospinal fluid hypersecretion in the choroid plexus epithelium. However, the pathogenesis of posthemorrhagic hydrocephalus remains unclear, and therapeutic strategies for prevention and treatment are lacking. In this study, an Nlrp3−/− rat model of intracerebral hemorrhage with ventricular extension and primary choroid plexus epithelial cell culture were used to investigate the potential effects of NLRP3-dependent lipid droplet formation and its role in the pathogenesis of posthemorrhagic hydrocephalus. The data indicated that NLRP3-mediated dysfunction of the blood–cerebrospinal fluid barrier (B-CSFB) accelerated neurological deficits and hydrocephalus, at least in part, through the formation of lipid droplets in the choroid plexus; these lipid droplets interacted with mitochondria and increased the release of mitochondrial reactive oxygen species that destroyed tight junctions in the choroid plexus after intracerebral hemorrhage with ventricular extension. This study broadens the current understanding of the relationship among NLRP3, lipid droplets and the B-CSFB and provides a new therapeutic target for the treatment of posthemorrhagic hydrocephalus. Strategies to protect the B-CSFB may be effective therapeutic approaches for posthemorrhagic hydrocephalus.
Scalar dark matter interpretation of the DAMPE data with U(1) gauge interactions
Cao, Junjie,Feng, Lei,Guo, Xiaofei,Shang, Liangliang,Wang, Fei,Wu, Peiwen American Physical Society 2018 Physical review. D Vol.97 No.9
<P>Recently, the Dark Matter Particle Explorer (DAMPE) experiment released the new measurement of the total cosmic e(+) e(-) flux between 25 GeV and 4.6 TeV, which indicates a spectral softening at around 0.9 TeV and a tentative peak at around 1.4 TeV. We utilize a scalar dark matter (DM) model to explain the DAMPE peak by XX -> Z'Z' -> l (l) over barl'(l) over bar 'l with an additional anomaly-free gauged U (l) family symmetry, in which X, Z'and l((')) denote, respectively, the scalar DM, the new gauge boson, and l((')) = e, mu, tau, with m(x) similar to m(z)' similar to 2 x 1.5 (TeV). We first illustrate that the minimal framework Gsm X U(l)(Y') with the above mass choices can explain the DAMPE excess, which, however, be excluded by LHC constraints from the Z' searches. Then, we study a nonminimal framework G(SM) X U(l)(Y') x U(i)(Y') in which U(l)(Y') mixes with U(l)(Y'). We show that such a framework can interpret the DAMPE data and at the same time survive all other constraints including the DM relic abundance, DM direct detection, and collider bounds. We also investigate the predicted e(+) e(-) spectrum in this framework and find that the mass splitting Delta m = m(x) - m(z') should be less than about 17 GeV to produce the peaklike structure.</P>