A Cloud Platform for the Integration and Optimizing Allocation of High Quality Teaching Resources based on the University-led Collaborative Innovation

Shugang Zhang,Zhenji Zhang,Xiaolan Guan 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.1

Collaborative innovation is an important strategy choice of China nowadays, and also of the national universities. Using SOA architecture and cloud computing, we build an integration and optimizing allocation cloud platform of high quality teaching resources for universities-led collaborative innovation to meet the resource requirements of universities based on the analysis of basic concept, types, core process, and evolution characteristics of university-led collaborative innovation following the inherent laws of university-led collaborative innovation, and then analyze the construction concept, logical architecture and main functions of the platform,. Finally, we provide a series of suggestions to the relevant universities and government departments to effectively promote the smooth implementation of the university-led collaborative innovation activities and the integration and optimizing allocation cloud platform of high quality teaching resources for university-led collaborative innovation.

Perioperative Comprehensive Supportive Care Interventions for Chinese Patients with Esophageal Carcinoma: a Prospective Study

Zhang, Xiao-Dan,Zhao, Qing-Yu,Fang, Yi,Chen, Guan-Xuan,Zhang, Hui-Fang,Zhang, Wen-Xiao,Yang, Xiao-Ping Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12

Objective: To assess the effects of perioperative comprehensive supportive care interventions on outcome of Chinese esophageal cancer patients in a prospective study. Methods: 60 patients with primary esophageal carcinoma were randomized into an intervention group (IG, n=31) and a control group (CG, n=29). The Chinese version of symptom checklist-90 (SCL-90) was adopted to assess their psychological status. The interventions, including health education, psychological support, stress management, coping strategies and behavior training, were carried out in 3 phases (preoperative, postoperative I and postoperative II), and psychological effects were thereafter evaluated accordingly before surgery, and 1 week, 4 weeks and 24 weeks post-surgery. Medical costs were estimated at discharge. Survival of patients was estimated each year post-surgery. General health status and satisfaction-with-hospital were surveyed by a follow-up questionnaire 4 years post-surgery. Results: All the subjects demonstrated higher scores in the preoperative phase than the normal range of Chinese population concerning 7 psychological domains including somatization, obsessive-compulsive, depression, anxiety, hostility, phobic anxiety and paranoid ideation. Although no significant difference was observed between the two groups at admission, the scores of IG, which tended to decrease at a faster rate, were generally lower than those of CG at weeks 1, 4 and 24 post-surgery. The length of hospital stay and medical costs of IG were significantly less than those of CG and satisfaction-with-hospital was better. However, there was no significant difference in 4-year survival or health status between two groups. Conclusions: Appropriate perioperative comprehensive supportive care interventions help to improve the psychological state of Chinese patients with esophageal carcinoma, to reduce health care costs and to promote satisfaction of patients and their families with hospital.

Visible light driven photocatalysis mediated <i>via</i> ligand-to-metal charge transfer (LMCT): an alternative approach to solar activation of titania

Zhang, Guan,Kim, Gonu,Choi, Wonyong The Royal Society of Chemistry 2014 ENERGY AND ENVIRONMENTAL SCIENCE Vol.7 No.3

<P>Visible light harvesting or utilization through semiconductor photocatalysis is a key technology for solar chemical conversion processes. Although titania nanoparticles are popular as a base material of photocatalysis, the lack of visible light activity needs to be overcome. This mini-review is focused on an uncommon approach to visible light activation of titania: the ligand-to-metal charge transfer (LMCT) that takes place between TiO<SUB>2</SUB> nanoparticles and surface adsorbates under visible light irradiation. We discuss a basic concept of photoinduced LMCT and the recent advances in LMCT-mediated visible light photocatalysis which has been applied in environmental remediation and solar energy conversion. Although the LMCT processes have been less investigated and limited in photocatalytic applications compared with other popular visible light activation methods such as impurity doping and dye sensitization, they provide lots of possibilities and flexibility in that a wide variety of organic or inorganic compounds can form surface complexes with TiO<SUB>2</SUB> and introduce a new absorption band in the visible light region. The LMCT complexes may serve as a visible light sensitizer that initiates the photocatalytic conversion of various substrates or the self-degradation of the ligand complexes (usually pollutants) themselves. We summarized and discussed various LMCT photocatalytic systems and their characteristics. The LMCT-mediated activation of titania and other wide bandgap semiconductors has great potential to be developed as a more general method of solar energy utilization in photocatalytic systems. More systematic design and utilization of LMCT complexes on semiconductors are warranted to advance the solar-driven chemical conversion processes.</P> <P>Graphic Abstract</P><P>In this mini-review we summarize the recent advances in the ligand-to-metal charge transfer (LMCT) mediated visible light photocatalysis on TiO<SUB>2</SUB> for environmental and energy applications. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3ee43147a'> </P>

Recyclable and stable ruthenium catalyst for free radical polymerization at ambient temperature initiated by visible light photocatalysis

Zhang, Guan,Song, In Young,Park, Taiho,Choi, Wonyong The Royal Society of Chemistry 2012 Green chemistry Vol.14 No.3

<P>A ruthenium complex catalyst immobilized on Nafion coated silica, SiO<SUB>2</SUB>/Nf/RuL, shows recyclable and stable photocatalytic activity for free radical polymerization at ambient temperature under mild visible light irradiation. The stable SiO<SUB>2</SUB>/Nf/RuL photocatalyst can be easily recycled by simple washing without chemical treatment, exhibiting high catalytic performance and no notable decrease in catalytic efficiency even after five test cycles.</P> <P>Graphic Abstract</P><P>A ruthenium complex catalyst immobilized on Nafion coated silica shows recyclable and stable photocatalytic activity for free radical polymerization at mild conditions. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2gc16409d'> </P>

A low-cost sensitizer based on a phenolic resin for charge-transfer type photocatalysts working under visible light

Zhang, Guan,Choi, Wonyong The Royal Society of Chemistry 2012 Chemical communications Vol.48 No.86

<P>Phenolic resin (denoted as PR) was used as an economical sensitizer of titania to achieve efficient visible light photocatalytic activity. Through the surface complexation of PR with TiO<SUB>2</SUB>, we demonstrate that the complexed PR layer sensitizes TiO<SUB>2</SUB> under visible light through the ligand-to-metal charge transfer (LMCT) mechanism.</P> <P>Graphic Abstract</P><P>Phenolic resin was used as an economical sensitizer of titania to achieve efficient visible light photocatalytic activity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cc35751h'> </P>

Guaranteeing Deadlines for Inter-Data Center Transfers

Zhang, Hong,Chen, Kai,Bai, Wei,Han, Dongsu,Tian, Chen,Wang, Hao,Guan, Haibing,Zhang, Ming Institute of Electrical and Electronics Engineers, 2017 IEEE/ACM transactions on networking Vol.25 No.1

<P>Inter-data center wide area networks (inter-DC WANs) carry a significant amount of data transfers that require to be completed within certain time periods, or deadlines. However, very little work has been done to guarantee such deadlines. The crux is that the current inter-DC WAN lacks an interface for users to specify their transfer deadlines and a mechanism for provider to ensure the completion while maintaining high WAN utilization. In this paper, we address the problem by introducing a deadline-based network abstraction (DNA) for inter-DC WANs. DNA allows users to explicitly specify the amount of data to be delivered and the deadline by which it has to be completed. The malleability of DNA provides flexibility in resource allocation. Based on this, we develop a system called Amoeba that implements DNA. Our simulations and test bed experiments show that Amoeba, by harnessing DNA's malleability, accommodates 15% more user requests with deadlines, while achieving 60% higher WAN utilization than prior solutions.</P>

Effect of laser beam incidence angle on cladding morphology in laser cladding process

Guan Zhang,Wenlei Sun,Dongmei Zhao,Pengfei Fan,Feng Guo,Yong Huang,Pengfei Li 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.4

The change of angle θ between laser cladding powder plane and substrate plane will lead to changes in cladding layer's geometric morphology. Therefore, we established a quantitative numerical prediction model for cladding layer geometry. In this model, we consider the variation of θ, the laser energy attenuation rate and the temperature rise of the powder particles. At the same time, the simulation results were verified by experiments. The results show that when θ is in the range of 50°~90°, the initial temperature is 298 K, the scanning speed is 3.75 mm/s, and the laser spot diameter is 4.5 mm, the Fe#1 powder cladding can achieve better forming effect on Q235. In general, with the decrease of θ, the height of the cladding layer decreases and the width of the layer increases. However, when θ is less than 50°, the quality of the formed morphology significantly deteriorated. The experimental results are in good agreement with the simulation results, which verifies the validity and reliability of the model. This work provides a theoretical reference for further understanding the relationship between the laser cladding morphology and the incident angle.

Identification of a Methyltransferase Encoded by Gene ste16 and Its Function in Ebosin Biosynthesis of Streptomyces sp. 139

Hong-Guan Xie,Yong-Gang Bao,Li-ping Bai,Jun-Jie Shan,Rong Jiang,Yang Zhang,Lian-Hong Guo,Ren Zhang,Yuan Li 한국미생물학회 2009 The journal of microbiology Vol.47 No.2

Streptomyces sp. 139 generates a novel exopolysaccharide (EPS) designated as Ebosin, which exerts an antagonistic effect on IL-1R in vitro and anti-rheumatic arthritis activity in vivo. A ste gene cluster for Ebosin biosynthesis consisting of 27 ORFs was previously identified in our laboratory. In this paper, ste16 was expressed in Escherichia coli BL21 and the recombinant protein was purified, which has the ability to catalyze the transfer of the methyl group from S-adenosylmethionine (AdoMet) to dTDP-4-keto-6-deoxy-D-glucos, which was thus identified as a methyltransferase. In order to determine the function of ste16 in Ebosin biosynthesis, the gene was disrupted with a double crossover via homologous recombination. The monosaccharide composition of EPS-m generated by the mutant strain Streptomyces sp. 139 (ste16-) was found to differ from that of Ebosin. The IL-1R antagonist activity of EPS-m was markedly lower than that of Ebosin. These experimental results have shown that the ste16 gene codes for a methyltransferase which is involved in Ebosin biosynthesis.

Chatbot Design Method Using Hybrid Word Vector Expression Model Based on Real Telemarketing Data

( Jie Zhang ),( Jianing Zhang ),( Shuhao Ma ),( Jie Yang ),( Guan Gui ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.4

In the development of commercial promotion, chatbot is known as one of significant skill by application of natural language processing (NLP). Conventional design methods are using bag-of-words model (BOW) alone based on Google database and other online corpus. For one thing, in the bag-of-words model, the vectors are Irrelevant to one another. Even though this method is friendly to discrete features, it is not conducive to the machine to understand continuous statements due to the loss of the connection between words in the encoded word vector. For other thing, existing methods are used to test in state-of-the-art online corpus but it is hard to apply in real applications such as telemarketing data. In this paper, we propose an improved chatbot design way using hybrid bag-of-words model and skip-gram model based on the real telemarketing data. Specifically, we first collect the real data in the telemarketing field and perform data cleaning and data classification on the constructed corpus. Second, the word representation is adopted hybrid bag-of-words model and skip-gram model. The skip-gram model maps synonyms in the vicinity of vector space. The correlation between words is expressed, so the amount of information contained in the word vector is increased, making up for the shortcomings caused by using bag-of-words model alone. Third, we use the term frequency-inverse document frequency (TF-IDF) weighting method to improve the weight of key words, then output the final word expression. At last, the answer is produced using hybrid retrieval model and generate model. The retrieval model can accurately answer questions in the field. The generate model can supplement the question of answering the open domain, in which the answer to the final reply is completed by long-short term memory (LSTM) training and prediction. Experimental results show which the hybrid word vector expression model can improve the accuracy of the response and the whole system can communicate with humans.

Induced Intermediate Mesoderm Combined with Decellularized Kidney Scaffolds for Functional Engineering Kidney

Jianye Zhang,Kailin Li,Feng Kong,Chao Sun,Denglu Zhang,Xin Yu,Xuesheng Wang,Xian Li,Tongyan Liu,Guangfeng Shao,Yong Guan,Shengtian Zhao 한국조직공학과 재생의학회 2019 조직공학과 재생의학 Vol.16 No.6

BACKGROUND: Chronic kidney disease is a severe threat to human health with no ideal treatment strategy. Mature mammalian kidneys have a fixed number of nephrons, and regeneration is difficult once they are damaged. For this reason, developing an efficient approach to achieve kidney regeneration is necessary. The technology of the combination of decellularized kidney scaffolds with stem cells has emerged as a new strategy; however, in previous studies, the differentiation of stem cells in decellularized scaffolds was insufficient for functional kidney regeneration, and many problems remain. METHODS: We used 0.5% sodium dodecyl sulfate (SDS) to produce rat kidney decellularized scaffolds, and induce adipose-derived stem cells (ADSCs) into intermediate mesoderm by adding Wnt agonist CHIR99021 and FGF9 in vitro. The characteristics of decellularized scaffolds and intermediate mesoderm induced from adipose–derived stem cells were identified. The scaffolds were recellularized with ADSCs and intermediate mesoderm cells through the renal artery and ureter. After cocultured for 10 days, cells adhesion and differentiation was evaluated. RESULTS: Intermediate mesoderm cells were successfully induced from ADSCs and identified by immunofluorescence and Western blotting assays (OSR1 ? , PAX2 ?). Immunofluorescence showed that intermediate mesoderm cells differentiated into tubular-like (E-CAD ? , GATA3 ?) and podocyte-like (WT1 ?) cells with higher differentiation efficiency than ADSCs in the decellularized scaffolds. Comparatively, this phenomenon was not observed in induced intermediate mesoderm cells cultured in vitro. CONCLUSION: In this study, we demonstrated that intermediate mesoderm cells could be induced from ADSCs and that they could differentiate well after cocultured with decellularized scaffolds.