Interoperative Radiotherapy of Seventy-two Cases of Early Breast Cancer Patients During Breast-conserving Surgery

Zhou, Shi-Fu,Shi, Wei-Feng,Meng, Dong,Sun, Chun-Lei,Jin, Jian-Rong,Zhao, Yu-Tian Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4

Objective: To evaluate interoperative radiotherapy after breast conservative surgery in early breast cancer patients in terms of postoperative complications, cosmetic outcome and recurrence events. Methods: From June 2007 to Dec 2011, 143 early breast cancer patients received breast conservative surgery. Seventy-two (study group) received interoperative radiotherapy, compared with 71 patients (control group) given routine radiotherapy. Postoperative complications were evaluated 1 month after surgery; cosmetic outcome was evaluated 1 year postoperatively; recurrence and death events were followed up. Results: The average wound healing time was 13~22 d in the study group and 9~14 d in the control group. In the study group, 2 patients developed lyponecrosis, 16 patients showed wound edema while no such side effects were found in the control group. No infection or hematomas were found in either group. In the study group (59 cases), overall cosmetic outcome in 53 patients was graded as excellent or good, and in 6 as fair or poor. Meanwhile in the control group (56 cases), 42 patients were graded as excellent or good, and 14 as fair or poor (P=0.032). After a follow-up from 3 to 54 months (median: 32 months), two patients (2.78%) in study group developed local relapses, one of them (1.39%) died, 2 patients (2.78%) developed bone metastases. In control group, one patient (1.41%) developed local relapse, 2 patients (2.82%) developed bone metastases, and no one died. Conclusion: Intraoperative radiotherapy is safe and reliable with good cosmetic outcome.

ON THE POWER SEQUENCE OF A FUZZY MATRIX CONVERGENT POWER SEQUENCE

Tian, Zhou,Liu, De-Fu 한국전산응용수학회 1997 Journal of applied mathematics & informatics Vol.4 No.1

The convergence of the power sequence of an $n{\times}n$ fuzzy matrix has been studied. Some theoretical necessary and sufficient con-ditions have been established for the power sequence to be convergent generally. Furthermore as one of our main concerns the convergence index was studied in detail especially for some special types of Boolean matrices. Also it has been established that the convergence index is bounded by $(n-1)^2+1$ from above for an arbitrary $n{\times}n$ fuzzy matrix if its power sequence converges. Our method is concentrated on the limit behavior of the power se-quence. It helped us to make our proofs be simpler and more direct that those in pure algebraic methods.

Model Approximation of Multiple Delay Transfer Function Models Using Multiple-Point Step Response Fitting

Ping Zhou,Bo Xiang,Jun Fu,Tian-You Chai 제어·로봇·시스템학회 2012 International Journal of Control, Automation, and Vol.10 No.1

Compared with model approximation for general SISO transfer function models with or without a single constant delay, the approximation problem for SISO transfer function models with multiple delays has received much less attention. In this paper, we attack this problem and thus present a multiple-point step response fitting based approximation method to derive the reduced models. A simple frequency-domain weighted recursive least squares (RLS) algorithm is proposed to determine a set of parameters so that the reduced models can approximate the original models by minimizing the defined frequency-domain squared-error between the step responses of the original and the reduced model. Numerical examples have demonstrated that the proposed approximation approach can not only introduce less dynamic approximation error, but also yield zero steady-state error.

Effect of Diclazuril on the Bursa of Fabricius Morphology and SIgA Expression in Chickens Infected with Eimeria tenella

Bian-hua Zhou,Li-li Liu,Jeffrey Liu,Fu-wei Yuan,Er-jie Tian,Hong-wei Wang 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.6

Chinese Sensitivity Analysis for a Compact Car Exterior Design

( Yoon Hyung Kun ),( Fu Ka Ili ),( Zhou Jun Jun ),( Zhuo Tian ) 한국감성과학회 2012 감성과학 Vol.15 No.2

This paper uses the sensibility engineering method to find the model of automobile most appealing to buyers in the 4th and 5th tier cities of China. Samples of class A & A0 cars were shown to 96 subjects in those cities to investigate their responses in relation to the concepts ``modern`` and ``smart``. The result shows that even though men tend to be more sensitive to automobile models in general than women are, both genders showed similar responses to specific models when they were asked to identify a model ``magnificent``, ``modern``, ``lively``, ``smart`` or ``cute``. This implies that despite the gender differences in terms of aesthetic sensitivity, both men and women share similar taste in relation to the appearance of cars. Apart from aesthetics, however, men tend to pay a greater attention to the details of design and material used for the cars, while women tend to pay attention to higher priced and better looking cars.

로고 유무에 따른 감성 분석

( Hyung Kun Yoon ),( Fu Kaili ),( Zhou Jun Jun ),( Zhuo Tian ) 한국감성과학회 2012 감성과학 Vol.15 No.3

This paper analyses the sensory responses of Chinese female consumers towards different designs of perfume bottles with particular attention to the existence of logos on them. We used total 40 samples of the perfume bottles, 20 with logos on them and 20 without, and the results show that young Chinese female consumers prefer simple designs over complex designs that contain different types of free curves with vivid colors. In addition, the existence of logos on bottles was found not to change the responses significantly, meaning that the logos on bottles do not affect sensibility of Chinese female towards perfume bottles. A logo`s impacts on the bottle depended in part on the bottle`s color and shape. Overall, a perfume bottle with simple shapes and light colors became regarded as more resplendent when the logo was added, but a bottle with more complex shapes and vivid colors tended to become regarded as plainer after adding the logo. This shows that a logo serves as a conciliatory element in the impression of the whole bottle in the ``resplendent-plain`` category.

Diversity of Duodenal and Rectal Microbiota in Biopsy Tissues and Luminal Contents in Healthy Volunteers(s)

( Gangping Li ),( Min Yang ),( Kan Zhou ),( Lei Zhang ),( Lugao Tian ),( Shangze Lv ),( Yu Jin ),( Wei Qian ),( Hanhua Xiong ),( Rong Lin ),( Yu Fu ),( Xiaohua Hou ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.7

The diverse microbial communities that colonize distinct segments of the gastrointestinal tract are intimately related to aspects of physiology and the pathology of human health. However, most recent studies have focused on the rectal or fecal microbiota, and the microbial signature of the duodenum is poorly studied. In this study, we compared the microbiota in duodenal and rectal samples to illustrate the characteristic microbial signatures of the duodenum in healthy adults. Nine healthy volunteers donated biopsies and luminal contents from the duodenum and rectum. To determine the composition and diversity of the microbiota, 454- pyrosequencing of bacterial 16S rRNA was performed and multiple bioinformatics analyses were applied. The α-diversity and phylogenetic diversity of the microbiota in the duodenal samples were higher than those of the rectal samples. There was higher biodiversity among the microbiota isolated from rectal biopsies than feces. Proteobacteria were more highly represented in the duodenum than in the rectum, both in the biopsies and in the luminal contents from the healthy volunteers (38.7% versus 12.5%, 33.2% versus 5.0%, respectively). Acinetobacter and Prevotella were dominant in the duodenum, whereas Bacteroides and Prevotella were dominant in the rectum. Additionally, the percentage of OTUs shared in biopsy groups was far higher than in the luminal group (43.0% versus 26.8%) and a greater number of genera was shared among the biopsies than the luminal contents. Duodenal samples demonstrated greater biological diversity and possessed a unique microbial signature compared with the rectum. The mucosa-associated microbiota was more relatively conserved than luminal samples.

Bile Acid Transporters Are Expressed and Heterogeneously Distributed in Rat Bile Ducts

Zhu-lin Luo,Long Cheng,Tao Wang,Li-jun Tang,Fu-zhou Tian,Ke Xiang,Lin Cui 거트앤리버 소화기연관학회협의회 2019 Gut and Liver Vol.13 No.5

Background/Aims: Cholangiocytes are capable of reabsorbing bile salts from bile, but the pathophysiological significance of this process is unclear. To this end, we detected the expression and distribution of bile acid transport proteins in cholangiocytes from normal rat liver and analyzed the possible pathophysiological significance. Methods: Bile duct tissues of Sprague-Dawley rats were isolated by enzymatic digestion and mechanical isolation, and then divided into large and small bile duct tissues. Immunohistochemistry, real-time polymerase chain reaction and Western blotting were used to determine the expression of the apical sodium-dependent bile acid transporter (ASBT), ileal bile acid binding protein (IBABP), and basolateral organic solute transporter α (Ostα) in the biliary tract system of rats. Differences in the expression and distribution of these proteins were analyzed. Results: In cholangiocytes, ASBT and IBABP were mainly expressed in cholangiocytes of the large bile ducts, in which the expression of both was significantly higher than that in the small ducts (p<0.05). Ostα was simultaneously expressed in cholangiocytes of both the large and small bile ducts, showing no significant difference in expression between the two groups of bile ducts (p>0.05). Conclusions: Bile acid transporters are expressed and heterogeneously distributed in rat bile ducts, indicating that bile acid reabsorption by cholangiocytes might mainly occur in the large bile ducts. These findings may help explore the physiology of bile ducts and the pathogenesis of various cholangiopathies.