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        The Relationship Between the Oxytocin Level and Rejection Sensitivity, Childhood Traumas, and Attachment Styles in Borderline Personality Disorder

        Fatma Kartal,Kerim Uğur,Burak Mete,Mehmet Emin Demirkol,Lut Tamam 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.3

        Objective In this study, it is aimed to investigate the relationship between the oxytocin level and the rejection sensitivity, childhood mental traumas, and attachment styles in patients diagnosed with borderline personality disorder (BPD).Methods Participants between the ages of 18–30 were included in the study. The patient group consists of 31 participants and the healthy control group consists of 31 participants. Sociodemographic/Clinical Variables Questionnaire, Relationship Scales Questionnaire, Rejection Sensitivity Questionnaire and Childhood Trauma Questionnaire were administered to the participants included in the study. Serum oxytocin levels of the participants were measured using the Elisa method.Results The oxytocin levels were found to be significantly lower in patients with BPD than in healthy control subjects, whereas the rejection sensitivity and childhood traumas were found to be significantly higher. No difference was found between the patient and control groups in terms of attachment styles, yet it was determined that there may be differences between the oxytocin levels of the BPD patients according to the attachment styles the patients have.Conclusion In conclusion, the findings of this study revealed that the rejection sensitivity in BPD patients is not associated with oxytocin levels and childhood traumas, indicating the need to assess the BPD patients in terms of other biopsychosocial factors related to the etiopathogenesis of BPD.

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        Evaluation of Cholinesterase Inhibitory and Antioxidant Activities of Wild and Cultivated Samples of Sage (Salvia fruticosa) by Activity-Guided Fractionation

        Fatma Sezer Şenol,Ilkay Erdogan Orhan,Sinem Aslan Erdem,Murat Kartal,Bilge Şener,Yu¨ksel Kan,Ferhat Celep,Ahmet Kahraman,Musa Dogan 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.11

        In European folk medicine, Salvia species have traditionally been used to enhance memory. In our previous study of 55 Salvia taxa, we explored significant anticholinesterase activity of cultivated S. fruticosa. In this study, we compared the inhibitory activity of dichloromethane, ethyl acetate, and ethanol extracts of 3 wild-grown samples and 1 cultivated sample of S. fruticosa against acetylcholinesterase and butyrylcholinesterase enzymes (which are associated with pathogenesis of Alzheimer's disease) by using the spectrophotometric Ellman method. Antioxidant activities were assessed by determining 2,2-diphenyl-1-picrylhydrazyl radical–scavenging activity, iron-chelating capacity, and ferric-reducing antioxidant power. The dichloromethane extract of the cultivated sample was then subjected to fractionation by using open column chromatography and medium-pressure liquid chromatography to obtain the most active fraction by activity-guided fractionation. All fractions and subfractions were tested in the same manner, and inactive subfractions were discarded. The essential oil of the cultivated sample was analyzed by gas chromatography–mass spectrometry.

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        Healthy Eating Index (HEI-2015) of Female College Students According to Obesity and Exercise Participation

        Gizem Helvacı,Fatma Tayhan Kartal,Nurcan Yabancı Ayhan 대한비만학회 2021 The Korean journal of obesity Vol.30 No.3

        Background: Individuals participating in exercise are more likely to lead a healthy lifestyle to achieve their exercise-related goals. This study aimed to examine the differences in dietary quality of female university students by exercise involvement and body mass index (BMI). Methods: This study was conducted with 360 female university students in Turkey. Students were asked to complete a questionnaire containing general characteristics and food consumption records. The “Healthy Eating Index (HEI-2015)” score was calculated using the results of food consumption records. Results: The findings showed that the ratio of individuals who exercised regularly was 34.2%. The ratio (44.2%) of regularly exercising participants with moderate/good diet quality was greater than that of regularly exercising participants with poor diet quality (30.6%) (P=0.016). There was no significant difference between the scores of overall diet quality according to BMI classification (P>0.05). The score (45.3±13.4) for overall diet quality of those participating in exercise in the group with normal body weight was higher than the score (41.5±12.1) for overall diet quality of those not participating in exercise (P=0.026). Those participating in exercise in the group with normal body weight consumed more greens and beans, whole grains, dairy products, seafood/vegetable proteins, and refined grains than those not participating in exercise (P<0.05). Conclusion: The rate of overall participation in physical activity was low. However, students participating in physical activity and with a normal body weight had a better diet quality. Creating an ideal environment that encourages students to participate in physical activity at universities can be an effective method for improving their diet quality.

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