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      • KCI등재

        Mechanism of MnS Precipitation on Al2O3–SiO2 Inclusions in Non‑oriented Silicon Steel

        Fangjie Li,Huigai Li,Di Huang,Shaobo Zheng,Jinglin You 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.6

        This study investigates the mechanism of MnS precipitation on Al2O3–SiO2 inclusions during the solidification of nonorientedsilicon steel, especially the influence of the phase structures and sizes of the oxides on the MnS precipitation, byscanning electron microscopy and transmission electron microscopy coupled with energy dispersive spectrometry. Theinvestigation results show that MnS tends to nucleate on submicron-sized Al2O3–SiO2 inclusions formed by interdendriticsegregation and that it covers the oxides completely. In addition, MnS can precipitate on micron-sized oxides and its precipitationbehavior is governed by the phase structure of the oxides. The MnS embryo formed in a MnO-containing oxidecan act as a substrate for MnS precipitation, thus permitting further growth via diffusion of solute atoms from the matrix. MnS also precipitates in a MnO-free oxide by the heterogeneous nucleation mechanism. Furthermore, MnS is less proneto precipitation in the Al2O3-rich regions of the Al2O3–SiO2 inclusions; this can be explained by the high lattice disregistrybetween MnS and Al2O3.

      • KCI등재

        Phytochemical and pharmacological properties of the genus Tamarix: a comprehensive review

        Li Fangjie,Xie Wenli,Ding Xianrui,Xu Kuo,Fu Xianjun 대한약학회 2024 Archives of Pharmacal Research Vol.47 No.5

        The genus Tamarix in the Tamaricaceae family consists of more than 100 species of halophyte plants worldwide that are mainly used to improve saline-alkali land and for coastal windbreaks, sand fixation, and afforestation in arid areas. A considerable number of species in this genus are also used as traditional medicines to treat various human diseases, especially in Asian and African countries. This review presents a comprehensive summary of 655 naturally occurring compounds derived from the genus Tamarix, categorized into flavonoids (18.0%), phenols (13.9%), tannins (9.3%), terpenoids (10.5%), essential oils (31.0%), and others (17.3%). The investigation revealed that the crude extracts and phytochemicals of this genus exhibited significant therapeutic potential, including anti-inflammatory, anti-Alzheimer, anticancer, antidiabetic, antibacterial, and antifungal activities. Six species of Tamarix have anticancer effects by causing cancer cell death, inducing autophagy, and stopping cell division. Seven species from the same genus have the potential for treating diabetes by inhibiting α-glycosidase activity, suppressing human islet amyloid polypeptide, regulating blood glucose levels, and modulating autophagy or inflammation. The focus on antibacterial and antidiabetic effects is due to the presence of volatile oil and flavonoid components. Extensive research has been conducted on the biological activity of 30 constituents, including 15 flavonoids, 5 phenols, 3 terpenoids, 1 tannin, and 6 others. Therefore, future research should thoroughly study the mechanisms of action of these and similar compounds. This is the most comprehensive review of the phytochemistry and pharmacological properties of Tamarix species, with a critical assessment of the current state of knowledge.

      • KCI등재

        Influence of Cu2S Precipitates Dissolution on Ferrite Grain Growth During Heat Treatment in the Non-Oriented Electrical Steel Sheet

        Yuan Wu,Fangjie Li,Ting Wang,Dan Zhao,Hefei Huang,Huigai Li,Shaobo Zheng 대한금속·재료학회 2017 METALS AND MATERIALS International Vol.23 No.3

        The factor to deduce grain growth of non-oriented electrical steel sheet during heat treatment was researched in thispaper. Scanning electron microscope equipped with electron backscatter diffraction (EBSD), X-ray diffractionand transmission electron microscope were used to characterize the microstructure, dislocation density and precipitate,respectively. The EBSD results indicated that the grain size increased from 18.7 μm to 56 μm after heattreatment. Meanwhile, the characterization of grain size distribution, dislocation density and precipitates revealedthat the dissolution of Cu2S precipitates, which act as inhibitor, may lead to the grain growth. In addition, the pinningforce of grain boundary and the driving force of grain growth were calculated. Based on experiments resultsand theoretical calculations, the Cu2S precipitates with diameter of less than 39 nm and volume fraction of 1.74 ×10-4would be sufficient to inhibit the ferrite grain growth. Heat treatment provides an efficient way to prompt thegrain growth.

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        The Clinical Feature of Behçet’s Disease in Northeastern China

        Yingbin Shang,Shixin Han,Jiuhong Li,Qiushi Ren,Fangji Song,Hongduo Chen 연세대학교의과대학 2009 Yonsei medical journal Vol.50 No.5

        Purpose: Behçet’s disease (BD) is a chronic, relapsing, multi-system vasculitis of unknown aetiology with complicated and diversified clinical features predominantly involving oral and genital ulcers, and ocular and cutaneous lesions. The clinical features of this disease have been described to be different according to geographical areas and gender. We investigated the specific clinical features of BD patients in Northeastern China. Materials and Methods: 116 patients involved in this study fulfilled the classification criteria of the International Study Group for BD. The clinical manifestations and results of laboratory tests of BD were recorded in each patient. Results: The onset was typically between 20-39 years with a slight female predominance. Oral ulcers were the most common manifestation, followed by skin lesions, positive pathergy reaction/genital ulcers, and ocular lesions. Vascular lesion and epididymitis were rare in patients with BD. The frequency of erythema nodosum-like lesion and articular involvement were significantly higher in females, while gastrointestinal involvement was significantly higher in males. The results of laboratory tests showed that the human leukocyte antigen (HLA)-B*51 alleles were positive in 30.9% of patients and the immunological abnormities were present in some patients. Conclusion: The clinical features of BD showed geographical and gender difference. Genetic and immune factors might participate in aetiopathogenesis of BD. Purpose: Behçet’s disease (BD) is a chronic, relapsing, multi-system vasculitis of unknown aetiology with complicated and diversified clinical features predominantly involving oral and genital ulcers, and ocular and cutaneous lesions. The clinical features of this disease have been described to be different according to geographical areas and gender. We investigated the specific clinical features of BD patients in Northeastern China. Materials and Methods: 116 patients involved in this study fulfilled the classification criteria of the International Study Group for BD. The clinical manifestations and results of laboratory tests of BD were recorded in each patient. Results: The onset was typically between 20-39 years with a slight female predominance. Oral ulcers were the most common manifestation, followed by skin lesions, positive pathergy reaction/genital ulcers, and ocular lesions. Vascular lesion and epididymitis were rare in patients with BD. The frequency of erythema nodosum-like lesion and articular involvement were significantly higher in females, while gastrointestinal involvement was significantly higher in males. The results of laboratory tests showed that the human leukocyte antigen (HLA)-B*51 alleles were positive in 30.9% of patients and the immunological abnormities were present in some patients. Conclusion: The clinical features of BD showed geographical and gender difference. Genetic and immune factors might participate in aetiopathogenesis of BD.

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